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Karin Pelka
Karin Pelka
Assistant Professor, Gladstone-UCSF Institute of Genomic Immunology
在 gladstone.ucsf.edu 的电子邮件经过验证 - 首页
标题
引用次数
年份
Single-cell transcriptomic analyses reveal distinct immune cell contributions to epithelial barrier dysfunction in checkpoint inhibitor colitis
MF Thomas, K Slowikowski, K Manakongtreecheep, P Sen, N Samanta, ...
Nature Medicine, 1-14, 2024
2024
Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy
JH Chen, LT Nieman, M Spurrell, V Jorgji, L Elmelech, P Richieri, KH Xu, ...
Nature Immunology 25 (4), 644-658, 2024
52024
Spatial organization and cellular composition of immunity hubs in human colorectal cancer
MG Palshikar, M Spurrell, J Demaray, H Chen, S Engels, R Madhu, ...
Cancer Research 84 (6_Supplement), 5492-5492, 2024
2024
scRNAseq and TCR repertoire analysis identifies immune correlates of response to combined BRAF/MEK/PD1 inhibition in a phase 2 trial
H Yao, V Jorgji, AL Tang, D Lieb, SX Chao, DJ Stein, M Spurrell, ...
Cancer Research 84 (6_Supplement), 6555-6555, 2024
2024
Dual checkpoint T (h1) eamwork makes the anti-cancer dream work
A Dietl, A Ralser, K Pelka
Immunity 57 (3), 406-408, 2024
2024
Integrating spatial transcriptomics count data with Crescendo improves visualization and detection of spatial gene patterns
N Millard, JH Chen, MG Palshikar, K Pelka, M Spurrell, C Price, J He, ...
bioRxiv, 2024.03. 07.583997, 2024
2024
Author Correction: Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling
CA Lareau, LS Ludwig, C Muus, SH Gohil, T Zhao, Z Chiang, K Pelka, ...
Nature Biotechnology 41 (9), 1345-1345, 2023
22023
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility
CA Lareau, V Liu, C Muus, SD Praktiknjo, L Nitsch, P Kautz, K Sandor, ...
Nature protocols 18 (5), 1416-1440, 2023
162023
Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response
JH Chen, LT Nieman, M Spurrell, V Jorgji, P Richieri, KH Xu, R Madhu, ...
BioRxiv, 2023.04. 04.535379, 2023
162023
Targeting TBK1 to overcome resistance to cancer immunotherapy
Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ...
Nature 615 (7950), 158-167, 2023
472023
Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial
J Tian, JH Chen, SX Chao, K Pelka, M Giannakis, J Hess, K Burke, ...
Nature medicine 29 (2), 458-466, 2023
622023
1242 altered interactions between circulating and tissue-resident Cd8 T cells with the Colonic mucosa define Checkpoint inhibitor colitis
K Slowikowski, M Thomas, K Manakongtreecheep, P Sen, J Tantivit, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
12022
Integrative single cell and spatial transcriptomics of colorectal cancer reveals multicellular functional units that support tumor progression
I Avraham-Davidi, S Mages, J Klughammer, N Moriel, S Imada, M Hofree, ...
BioRxiv, 2022.10. 02.508492, 2022
132022
Abstract LB003: Combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients: Correlative studies from a phase 2 trial
J Tian, JH Chen, SX Chao, K Pelka, V Jorgji, I Baiev, WB Bradford, ...
Cancer Research 82 (12_Supplement), LB003-LB003, 2022
12022
A single-cell spatially resolved map of colorectal cancer identifies novel spatial relationships between cancer cells and the microenvironment
C Price, JH Chen, K Pelka, S Chao, M Therrien, T Wiggin, N Fernandez, ...
Cancer Research 82 (12_Supplement), 2030-2030, 2022
22022
SO-38 Clinical efficacy and single-cell analysis of combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients
R Corcoran, J Tian, J Chen, S Chao, K Pelka, I Baiev, P Sindurakar, ...
Annals of Oncology 33, S373, 2022
2022
Listening in on multicellular communication in human tissue immunology
JJ Albers, K Pelka
Frontiers in Immunology 13, 884185, 2022
32022
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
B Chen, S Cherie’R, ET McKinley, AJ Simmons, MA Ramirez-Solano, ...
Cell 184 (26), 6262-6280. e26, 2021
1692021
641 Spatially organized multicellular immune hubs in MMRd and MMRp colorectal cancer
J Chen, K Pelka, M Hofree, M Giannakis, G Boland, A Aguirre, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A670-A670, 2021
2021
920 A single-cell spatially resolved MERFISH map of the colorectal tumor immune microenvironment
C Price, J Chen, K Pelka, S Chao, J He, G Boland, G Emanuel, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
32021
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