A guide to complement biology, pathology and therapeutic opportunity DC Mastellos, G Hajishengallis, JD Lambris Nature Reviews Immunology 24 (2), 118-141, 2024 | 32 | 2024 |
A High-Performance Antibacterial Nanostructured ZnO Microfluidic Device for Controlled Bacterial Lysis and DNA Release Y Xesfyngi, M Georgoutsou-Spyridonos, A Tripathy, A Milionis, ... Antibiotics 12 (8), 1276, 2023 | | 2023 |
The Complement-Targeted Inhibitor Mini-FH Protects against Experimental Periodontitis via Both C3-Dependent and C3-Independent Mechanisms X Li, H Wang, CQ Schmidt, VP Ferreira, D Yancopoulou, DC Mastellos, ... The Journal of Immunology 211 (3), 453-461, 2023 | 1 | 2023 |
Temporal Pattern of Neuroinflammation Associated with a Low Glycemic Index Diet in the 5xFAD Mouse Model of Alzheimer’s Disease I Dafnis, C Mountaki, E Fanarioti, DC Mastellos, M Karvelas, ... Molecular Neurobiology 59 (12), 7303-7322, 2022 | 3 | 2022 |
Complement is required for microbe-driven induction of Th17 and periodontitis H Wang, H Ideguchi, T Kajikawa, DC Mastellos, JD Lambris, ... The Journal of Immunology 209 (7), 1370-1378, 2022 | 10 | 2022 |
Complement C3 inhibition in severe COVID-19 using compstatin AMY-101 P Skendros, G Germanidis, DC Mastellos, C Antoniadou, E Gavriilidis, ... Science Advances 8 (33), eabo2341, 2022 | 28 | 2022 |
Compstatins: the dawn of clinical C3-targeted complement inhibition C Lamers, DC Mastellos, D Ricklin, JD Lambris Trends in pharmacological sciences 43 (8), 629-640, 2022 | 41 | 2022 |
Recent developments in C3-targeted complement therapeutics DC Mastellos, JD Lambris Seminars in immunology 60, 101645, 2022 | 2 | 2022 |
Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde M Mannes, DC Mastellos, KN Ekdahl, B Nilsson, D Yancopoulou, ... Seminars in Immunology 60, 101640, 2022 | 6 | 2022 |
From discovery to approval: a brief history of the compstatin family of complement C3 inhibitors DC Mastellos, D Ricklin, G Sfyroera, A Sahu Clinical Immunology 235, 108785, 2022 | 40 | 2022 |
Emerging opportunities for C3 inhibition in the eye BJ Kim, T Liu, DC Mastellos, JD Lambris Seminars in Immunology 59, 101633, 2022 | 5 | 2022 |
C3-targeted host-modulation approaches to oral inflammatory conditions T Kajikawa, DC Mastellos, H Hasturk, GA Kotsakis, D Yancopoulou, ... Seminars in Immunology 59, 101608, 2022 | 11 | 2022 |
Phase IIa clinical trial of complement C3 inhibitor AMY-101 in adults with periodontal inflammation H Hasturk, G Hajishengallis, JD Lambris, DC Mastellos, D Yancopoulou The Journal of Clinical Investigation 131 (23), 2021 | 51 | 2021 |
Isothermal Recombinase Polymerase Amplification (RPA) of E. coli gDNA in Commercially Fabricated PCB-Based Microfluidic Platforms M Georgoutsou-Spyridonos, M Filippidou, GD Kaprou, DC Mastellos, ... Micromachines 12 (11), 1387, 2021 | 17 | 2021 |
Enhanced antibacterial activity of ZnO-PMMA nanocomposites by selective plasma etching in atmospheric pressure P Dimitrakellis, GD Kaprou, G Papavieros, DC Mastellos, V Constantoudis, ... Micro and Nano Engineering 13, 100098, 2021 | 18 | 2021 |
C3-targeted therapy in periodontal disease: moving closer to the clinic G Hajishengallis, H Hasturk, JD Lambris, DA Apatzidou, GN Belibasakis, ... Trends in immunology 42 (10), 856-864, 2021 | 34 | 2021 |
Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions BJ Kim, DC Mastellos, Y Li, JL Dunaief, JD Lambris Progress in retinal and eye research 83, 100936, 2021 | 46 | 2021 |
Is complement the culprit behind COVID-19 vaccine-related adverse reactions? DC Mastellos, P Skendros, JD Lambris The Journal of clinical investigation 131 (11), 2021 | 27 | 2021 |
Bactericidal Action of Smooth and Plasma Micro‐Nanotextured Polymeric Surfaces with Varying Wettability, Enhanced by Incorporation of a Biocidal Agent P Dimitrakellis, K Ellinas, GD Kaprou, DC Mastellos, A Tserepi, ... Macromolecular Materials and Engineering 306 (4), 2000694, 2021 | 26 | 2021 |
Efficacy matters: broadening complement inhibition in COVID-19 DC Mastellos, P Skendros, RT Calado, AM Risitano, JD Lambris The Lancet Rheumatology 3 (2), e95, 2021 | 5 | 2021 |