Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer H Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, ... Nature Genetics, 1-14, 2024 | | 2024 |
Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation VM Poort, R Hagelaar, MJ van Roosmalen, L Trabut, JG Buijs-Gladdines, ... Cancer Research, 2024 | | 2024 |
Polyketide synthase positive Escherichia coli one‐time measurement in stool is not informative of colorectal cancer risk in a screening setting W de Klaver, M de Wit, A Bolijn, M Tijssen, P Delis‐van Diemen, ... The Journal of Pathology 263 (2), 217-225, 2024 | | 2024 |
Direct detection of 8-oxo-dG using nanopore sequencing DMK van Soest, NJM Besselink, R Straver, JP Keijer, C Vermeulen, ... | | 2024 |
Mitochondrial H2O2 release does not directly cause damage to chromosomal DNA DMK van Soest, PE Polderman, WTF den Toom, JP Keijer, ... Nature Communications 15 (1), 2725, 2024 | 2 | 2024 |
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer AR Huber, C Pleguezuelos-Manzano, J Puschhof, J Ubels, C Boot, ... Cancer Cell 42 (3), 487-496. e6, 2024 | 3 | 2024 |
Evaluating offspring Genomic and Epigenomic alterations after prenatal exposure to Cancer treatment In Pregnancy (GE-CIP): a multicentric observational study I Struys, C Velázquez, K Devriendt, L Godderis, H Segers, B Thienpont, ... BMJ open 14 (3), e081833, 2024 | | 2024 |
Direct detection of 8-oxo-dG using nanopore sequencing M Pages-Gallego, DMK van Soest, NJM Besselink, R Straver, JP Keijer, ... bioRxiv, 2024.05. 17.594638, 2024 | | 2024 |
Single-Cell Whole-Genome Sequencing after Chemotherapeutic Treatment Reveals Cell Type-Specific Mutational Burdens LLM Derks, I Van Der Werf, L Trabut, E Bertrums, J De Kanter, AR Huber, ... Blood 142, 4136, 2023 | | 2023 |
Transient Differentiation-State Plasticity during Initiation of Pediatric Acute Lymphoblastic Leukemia VM Poort, R Hagelaar, M van Roosmalen, L Trabut, JG Buijs-Gladdines, ... Blood 142, 42, 2023 | | 2023 |
Single-cell evaluation of DNA damage in neonatal hematopoietic cells after prenatal exposure to chemotherapy I Struys, C Velázquez, J Ubels, M Ghosh, J Geurts, C Lejeune, W Bossuyt, ... EMBL Cancer Genomics, Date: 2023/11/15-2023/11/17, Location: Heiderlberg …, 2023 | | 2023 |
SELECTIVE PRESSURES OF PLATINUM COMPOUNDS SHAPE THE EVOLUTION OF THERAPY-RELATED MYELOID NEOPLASMS E Bertrums, J De Kanter, M Verheul, M Van Roosmalen, H Hasle, ... PEDIATRIC BLOOD & CANCER 70, S105-S105, 2023 | | 2023 |
Stem cell mutations, associated cancer risk, and consequences for regenerative medicine LLM Derks, R van Boxtel Cell Stem Cell, 2023 | 6 | 2023 |
Chemotherapy during pregnancy is associated with increased genotoxicity and mutational load in the fetal hematopoietic compartment. I Struys, C Velázquez, J Ubels, A van Leeuwen, M Ghosh, J Geurts, ... ESGO, Date: 2023/09/28-2023/10/01, Location: Istanbul, Turkey, 2023 | | 2023 |
Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox S Middelkamp, F Manders, F Peci, MJ van Roosmalen, DM González, ... Cell genomics 3 (9), 2023 | 4 | 2023 |
# 506 Chemotherapy during pregnancy is associated with increased genotoxicity and mutational load in the fetal hematopoietic compartment I Struys, C Velázquez, J Ubels, A Van Leeuwen, M Ghosh, J Geurts, ... International Journal of Gynecologic Cancer 33 (Suppl 3), 2023 | | 2023 |
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids MH Geurts, S Gandhi, MG Boretto, N Akkerman, LLM Derks, G van Son, ... Nature Communications 14 (1), 4998, 2023 | 6 | 2023 |
What drives pediatric Burkitt lymphoma? Timing events in the evolution of cancer using single‐cell whole genome sequencing. A Steemers, J de Kanter, N Groenen, DM Gonzalez, M Verheul, L Trabut, ... Hematological Oncology 41, 2023 | | 2023 |
RNF43 mutations facilitate mucinous colorectal cancer metastasis via formation of a tumour-intrinsic niche JM Bugter, L El Bouazzaoui, E Küçükköse, Y Hong, J Sprangers, ... bioRxiv, 2022.12. 22.521159, 2022 | | 2022 |
Mutation accumulation in mtDNA of cancers resembles mutagenesis in normal stem cells F Manders, J van Dinter, R van Boxtel Iscience 25 (12), 2022 | 1 | 2022 |