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Ruben van Boxtel
Ruben van Boxtel
Principal Investigator
在 prinsesmaximacentrum.nl 的电子邮件经过验证 - 首页
标题
引用次数
年份
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer
H Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, ...
Nature Genetics, 1-14, 2024
2024
Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
VM Poort, R Hagelaar, MJ van Roosmalen, L Trabut, JG Buijs-Gladdines, ...
Cancer Research, 2024
2024
Polyketide synthase positive Escherichia coli one‐time measurement in stool is not informative of colorectal cancer risk in a screening setting
W de Klaver, M de Wit, A Bolijn, M Tijssen, P Delis‐van Diemen, ...
The Journal of Pathology 263 (2), 217-225, 2024
2024
Direct detection of 8-oxo-dG using nanopore sequencing
DMK van Soest, NJM Besselink, R Straver, JP Keijer, C Vermeulen, ...
2024
Mitochondrial H2O2 release does not directly cause damage to chromosomal DNA
DMK van Soest, PE Polderman, WTF den Toom, JP Keijer, ...
Nature Communications 15 (1), 2725, 2024
22024
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
AR Huber, C Pleguezuelos-Manzano, J Puschhof, J Ubels, C Boot, ...
Cancer Cell 42 (3), 487-496. e6, 2024
32024
Evaluating offspring Genomic and Epigenomic alterations after prenatal exposure to Cancer treatment In Pregnancy (GE-CIP): a multicentric observational study
I Struys, C Velázquez, K Devriendt, L Godderis, H Segers, B Thienpont, ...
BMJ open 14 (3), e081833, 2024
2024
Direct detection of 8-oxo-dG using nanopore sequencing
M Pages-Gallego, DMK van Soest, NJM Besselink, R Straver, JP Keijer, ...
bioRxiv, 2024.05. 17.594638, 2024
2024
Single-Cell Whole-Genome Sequencing after Chemotherapeutic Treatment Reveals Cell Type-Specific Mutational Burdens
LLM Derks, I Van Der Werf, L Trabut, E Bertrums, J De Kanter, AR Huber, ...
Blood 142, 4136, 2023
2023
Transient Differentiation-State Plasticity during Initiation of Pediatric Acute Lymphoblastic Leukemia
VM Poort, R Hagelaar, M van Roosmalen, L Trabut, JG Buijs-Gladdines, ...
Blood 142, 42, 2023
2023
Single-cell evaluation of DNA damage in neonatal hematopoietic cells after prenatal exposure to chemotherapy
I Struys, C Velázquez, J Ubels, M Ghosh, J Geurts, C Lejeune, W Bossuyt, ...
EMBL Cancer Genomics, Date: 2023/11/15-2023/11/17, Location: Heiderlberg …, 2023
2023
SELECTIVE PRESSURES OF PLATINUM COMPOUNDS SHAPE THE EVOLUTION OF THERAPY-RELATED MYELOID NEOPLASMS
E Bertrums, J De Kanter, M Verheul, M Van Roosmalen, H Hasle, ...
PEDIATRIC BLOOD & CANCER 70, S105-S105, 2023
2023
Stem cell mutations, associated cancer risk, and consequences for regenerative medicine
LLM Derks, R van Boxtel
Cell Stem Cell, 2023
62023
Chemotherapy during pregnancy is associated with increased genotoxicity and mutational load in the fetal hematopoietic compartment.
I Struys, C Velázquez, J Ubels, A van Leeuwen, M Ghosh, J Geurts, ...
ESGO, Date: 2023/09/28-2023/10/01, Location: Istanbul, Turkey, 2023
2023
Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox
S Middelkamp, F Manders, F Peci, MJ van Roosmalen, DM González, ...
Cell genomics 3 (9), 2023
42023
# 506 Chemotherapy during pregnancy is associated with increased genotoxicity and mutational load in the fetal hematopoietic compartment
I Struys, C Velázquez, J Ubels, A Van Leeuwen, M Ghosh, J Geurts, ...
International Journal of Gynecologic Cancer 33 (Suppl 3), 2023
2023
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids
MH Geurts, S Gandhi, MG Boretto, N Akkerman, LLM Derks, G van Son, ...
Nature Communications 14 (1), 4998, 2023
62023
What drives pediatric Burkitt lymphoma? Timing events in the evolution of cancer using single‐cell whole genome sequencing.
A Steemers, J de Kanter, N Groenen, DM Gonzalez, M Verheul, L Trabut, ...
Hematological Oncology 41, 2023
2023
RNF43 mutations facilitate mucinous colorectal cancer metastasis via formation of a tumour-intrinsic niche
JM Bugter, L El Bouazzaoui, E Küçükköse, Y Hong, J Sprangers, ...
bioRxiv, 2022.12. 22.521159, 2022
2022
Mutation accumulation in mtDNA of cancers resembles mutagenesis in normal stem cells
F Manders, J van Dinter, R van Boxtel
Iscience 25 (12), 2022
12022
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