Transmembrane TNF-TNFR2 signaling as a critical immunoregulatory node in pancreatic cancer EM Dickey, A Bianchi, H Amirian, PJ Hosein, D Faustman, R Brambilla, ... Oncoimmunology 13 (1), 2326694, 2024 | | 2024 |
Su1179 MICROBIAL METABOLITE UROLITHIN A REDUCES INFLAMMATION AND ENHANCES GUT BARRIER FUNCTION IN KRASG12D INHIBITOR MRTX1133-TREATED MOUSE MODELS OF PANCREATIC CANCER V Krishnamoorthy, S Mehra, S Jinka, H Amirian, EW Box, S Singh, ... Gastroenterology (New York, NY 1943) 166 (5), S-686-S-686, 2024 | | 2024 |
Patient metabolic profile defined by liver and muscle 18F-FDG PET avidity is independently associated with overall survival in gastric cancer GA Vitiello, VS Jayaprakasam, LH Tang, MA Schattner, YY Janjigian, ... Gastric Cancer 27 (3), 548-557, 2024 | | 2024 |
Tumor Cell–Intrinsic p38 MAPK Signaling Promotes IL1α-Mediated Stromal Inflammation and Therapeutic Resistance in Pancreatic Cancer SP Singh, AR Dosch, S Mehra, I De Castro Silva, A Bianchi, VT Garrido, ... Cancer Research 84 (8), 1320-1332, 2024 | 2 | 2024 |
Improving patient stratification and selection for curative-intent treatment in localized pancreatic cancer MP Martos, H Amirian, EM Dickey, EW Box, NB Merchant, PJ Hosein, ... Hepatobiliary Surgery and Nutrition 13 (2), 325, 2024 | | 2024 |
CREB-ROCK driven extracellular matrix remodeling exasperates pancreatic cancer progression S Jinka, S Mehra, V Krishnamoorthy, A Bianchi, K Rajkumar, A Adams, ... Cancer Research 84 (6_Supplement), 4277-4277, 2024 | | 2024 |
Black Race and CA 19-9 Nonproduction is Associated with Limited Pathologic Response to Neoadjuvant Chemotherapy in Patients with Localized Pancreatic Cancer MP Martos, EM Dickey, UR Yanala, K Abdilleh, I Ogobuiro, EW Box, ... ANNALS OF SURGICAL ONCOLOGY 31 (1), S167-S168, 2024 | | 2024 |
Association of race and CA 19-9 nonproduction with limited pathologic response to neoadjuvant chemotherapy in patients with localized pancreatic cancer. MP Martos, EM Dickey, UR Yanala, K Abdilleh, I Ogobuiro, EW Box, ... Journal of Clinical Oncology 42 (3_suppl), 609-609, 2024 | | 2024 |
A phase 1 trial of combined MEK, STAT3 and PD-1 inhibition in metastatic pancreatic ductal adenocarcinoma (PDAC). PJ Hosein, J Datta, N Ezenwajiaku, Z Zhou, MV Yow, M Boone, ... Journal of Clinical Oncology 42 (3_suppl), TPS713-TPS713, 2024 | 1 | 2024 |
Utility of circulating tumor DNA (ctDNA) for the detection of minimal residual disease (MRD) after curative-intent therapy for patients with localized pancreatic adenocarcinoma … UR Yanala, MP Martos, EM Dickey, AM Corona, N Ezenwajiaku, ... Journal of Clinical Oncology 42 (3_suppl), 695-695, 2024 | | 2024 |
Molecular differences with therapeutic implications in early-onset compared to average-onset cholangiocarcinoma. T Jayakrishnan, Y Baca, J Xiu, M Patel, BA Weinberg, E Lou, J Datta, ... Journal of Clinical Oncology 42 (3_suppl), 536-536, 2024 | | 2024 |
Abstract C002: Interleukin-1 receptor accessory protein (IL1RAP) overexpression is associated with worse prognosis in PDAC and is targetable by nadunolimab E Van Cutsem, K Abdilleh, J Datta, M Hidalgo, CR Millrud, P Skoog, ... Cancer Research 84 (2_Supplement), C002-C002, 2024 | | 2024 |
Abstract C064: Chronic platinum exposure induces cell-intrinsic type1 interferon/STING pathway activation in homologous recombination-deficient pancreatic cancer to drive … I Ogobuiro, A Bianchi, L Caeiro, H Amirian, L Nivelo, I De Castro Silva, ... Cancer Research 84 (2_Supplement), C064-C064, 2024 | | 2024 |
Abstract B093: Alcoholic chronic inflammation driven CREB mediates acinar-to-ductal reprogramming and promote neoplastic progression S Mehra, S Srinivasan, A Bianchi, A Dosch, S Singh, V Garrido, ... Cancer Research 84 (2_Supplement), B093-B093, 2024 | | 2024 |
Abstract C021: Granulocytic MDSC-derived NLRP3 inflammasome activation is a novel regulator of inflammatory CAF skewness in pancreatic cancer K Rajkumar, NU Deshpande, I de Castro Silva, A Bianchi, I Ogobuiro, ... Cancer Research 84 (2_Supplement), C021-C021, 2024 | | 2024 |
Abstract C025: Fibroblast-specific IL1R1-p38 MAPK signaling sustains stromal inflammation and contributes to therapeutic resistance in pancreatic cancer SP Singh, AR Dosch, S Mehra, I de Castro Silva, VT Garrido, A Bianchi, ... Cancer Research 84 (2_Supplement), C025-C025, 2024 | | 2024 |
Abstract PR16: Neutrophil-intrinsic tumor necrosis factor (TNF) is a novel driver of T-cell and cancer-associated fibroblast (CAF) dysfunction in pancreatic cancer A Bianchi, H Amirian, I De Castro Silva, I Ogobuiro, K Rajkumar, ... Cancer Research 84 (2_Supplement), PR16-PR16, 2024 | | 2024 |
Alcoholic chronic inflammation driven CREB mediates acinar-to-ductal reprogramming and promote neoplastic progression S Mehra, S Srinivasan, A Bianchi, A Dosch, S Singh, V Garrido, IDC Silva, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
Neutrophil-intrinsic tumor necrosis factor (TNF) is a novel driver of T-cell and cancer-associated fibroblast (CAF) dysfunction in pancreatic cancer A Bianchi, H Amirian, IDC Silva, I Ogobuiro, K Rajkumar, AM Adams, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
Chronic platinum exposure induces cell-intrinsic type1 interferon/STING pathway activation in homologous recombination-deficient pancreatic cancer to drive sensitivity to … I Ogobuiro, A Bianchi, L Caeiro, H Amirian, L Nivelo, IDC Silva, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |