Transcriptomic analysis of AHR wildtype and Knock-out rat livers supports TCDD's role in AHR/ARNT-mediated circadian disruption and hepatotoxicity ME Andersen, AR Barutcu, MB Black, JA Harrill Toxicology and Applied Pharmacology 487, 116956, 2024 | 1 | 2024 |
A Comparison of In Vitro Points of Departure with Human Blood Levels for Per-and Polyfluoroalkyl Substances (PFAS) RS Judson, D Smith, M DeVito, JF Wambaugh, BA Wetmore, ... Toxics 12 (4), 271, 2024 | | 2024 |
Transcriptomics‐Based Points of Departure for Daphnia magna Exposed to 18 Per‐ and Polyfluoroalkyl Substances DL Villeneuve, BR Blackwell, K Bush, J Harrill, F Harris, M Hazemi, M Le, ... Environmental Toxicology and Chemistry, 2024 | 1 | 2024 |
High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes JD Rogers, FDL Leusch, B Chambers, KD Daniels, LJ Everett, R Judson, ... Environmental Science & Technology 58 (4), 2027-2037, 2024 | 1 | 2024 |
Investigating the mode of action for wasting produced by tetrachlorodibenzo-p-dioxin (TCDD) in rats using transcriptomics: Evidence for roles of AHR and ARNT in circadian cycling ME Andersen, R Barutcu, MB Black, J Harrill bioRxiv, 2024.03. 02.583130, 2024 | 2 | 2024 |
Exploring the effects of experimental parameters and data modeling approaches on in vitro transcriptomic point-of-departure estimates JA Harrill, LJ Everett, DE Haggard, JL Bundy, CM Willis, I Shah, ... Toxicology 501, 153694, 2024 | 1 | 2024 |
New approach methodologies in human regulatory toxicology–Not if, but how and when! S Schmeisser, A Miccoli, M von Bergen, E Berggren, A Braeuning, ... Environment International 178, 108082, 2023 | 53 | 2023 |
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity TW Gant, SS Auerbach, M Von Bergen, M Bouhifd, PA Botham, F Caiment, ... Archives of toxicology 97 (8), 2291-2302, 2023 | 5 | 2023 |
Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments J Nyffeler, C Willis, FR Harris, MJ Foster, B Chambers, M Culbreth, ... Toxicology and Applied Pharmacology 468, 116513, 2023 | 12 | 2023 |
From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow AJF Reardon, R Farmahin, A Williams, MJ Meier, GC Addicks, CL Yauk, ... Frontiers in Toxicology 5, 1194895, 2023 | 14 | 2023 |
Navigating transcriptomic connectivity mapping workflows to link chemicals with bioactivities I Shah, J Bundy, B Chambers, LJ Everett, D Haggard, J Harrill, RS Judson, ... Chemical research in toxicology 35 (11), 1929-1949, 2022 | 6 | 2022 |
An expert-driven literature review of “negative” chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation MM Martin, NC Baker, WK Boyes, KE Carstens, ME Culbreth, ME Gilbert, ... Neurotoxicology and Teratology 93, 107117, 2022 | 8 | 2022 |
1.1. Descriptive full-text title J Harrill, T Shafer | | 2022 |
High-Throughput Transcriptomics and Chemical Toxicity Testing: Quality Control Approaches to Enhance Consistency and Reproducibility MJ Meier, A Williams, KB Cook, CJ Corton, LJ Everett, JA Harrill, CL Yauk ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 63, 40-40, 2022 | | 2022 |
High-Throughput Molecular Profiling Assays and Potential Applications in Chemical Risk Assessment JA Harrill ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 63, 23-23, 2022 | | 2022 |
Deriving an Optimal Transcriptomic Metric to Establish Protective and Relevant Transcriptomic Points of Departure for Risk Assessment Application AJF Reardon, R Farmahin, M Meier, A Williams, G Addicks, C Yauk, ... ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 63, 89-90, 2022 | | 2022 |
Benchmark Dose Modeling Approaches for Volatile Organic Chemicals Using a Novel Air-Liquid Interface In Vitro Exposure System AM Speen, JR Murray, QT Krantz, D Davies, P Evansky, JA Harrill, ... Toxicological Sciences 188 (1), 88-107, 2022 | 6 | 2022 |
Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example J Nyffeler, C Willis, FR Harris, LW Taylor, R Judson, LJ Everett, JA Harrill Toxicology and applied pharmacology 444, 116032, 2022 | 9 | 2022 |
Integrating Data From In Vitro New Approach Methodologies for Developmental Neurotoxicity KE Carstens, AF Carpenter, MM Martin, JA Harrill, TJ Shafer, ... Toxicological Sciences 187 (1), 62-79, 2022 | 25 | 2022 |
Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity Screening M Culbreth, J Nyffeler, C Willis, JA Harrill Frontiers in Toxicology 3, 803987, 2022 | 2 | 2022 |