| Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in app/ps1 mice G Rodriguez, M Eren, I Haupfear, KL Viola, EN Cline, T Miyata, WL Klein, ... Psychopharmacology 240 (12), 2641-2655, 2023 | 2 | 2023 |
| Plasminogen Activator Inhibitor-1 (PAI-1) is an Essential Driver of Cardiovascular Aging in Mice A Kalousdian, S Soberanes, M Eren, E Jorgensen, E Lux, LD Wilsbacher, ... Circulation 148 (Suppl_1), A14009-A14009, 2023 | | 2023 |
| Mouse model hints at pharmacogenomic strategies for stroke treatment in patients possessing a risk variant DE Vaughan The Journal of Clinical Investigation 133 (18), e173932-e173932, 2023 | | 2023 |
| Associations between GrimAge acceleration and pulmonary function in the Coronary Artery Risk Development in Young Adults (CARDIA) study BT Joyce, X Chen, T Gao, Y Zheng, DR Nannini, L Liu, BE Henkle, ... Epigenomics 15 (13), 693-703, 2023 | | 2023 |
| Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status K Kim, BT Joyce, DR Nannini, Y Zheng, P Gordon-Larsen, JM Shikany, ... Science Advances 9 (26), eadf8140, 2023 | 12 | 2023 |
| Inclusion of epigenetic age acceleration in oncological trials BB Mittal, DE Vaughan The Lancet Healthy Longevity 4 (5), e185-e186, 2023 | | 2023 |
| Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload AK Ghosh, AA Kalousdian, M Shang, E Lux, M Eren, A Keating, ... Cellular Signalling 104, 110555, 2023 | 4 | 2023 |
| Heterozygous PAI-1 Deficiency’s Role in Pathological Aging in the Human Cardiovascular System A Nelson, D Vaughan Proceedings of IMPRS 6 (1), 2023 | | 2023 |
| Plasminogen Activator Inhibitor-1 Drives Myocardial Substrate Preference in Mice With Diet-Induced Obesity A Kalousdian, SS Khan, LD Wilsbacher, M Eren, D Procissi, AK Ghosh, ... CIRCULATION RESEARCH 131 (12), E179-E179, 2022 | | 2022 |
| Cardiomyocyte PAI-1 Limits the Extent of Cardiac Pathology in Response to Left Ventricular Pressure Overload AK Ghosh, A Kalousdian, M Shang, E Lux, M Eren, A Keating, ... CIRCULATION RESEARCH 131 (12), E185-E185, 2022 | | 2022 |
| Effects of Plasminogen Activator Inhibitor-1 on the Circadian Clock in Liver LD Wilsbacher, JA Levine, M Eren, M Shang, A Kalousdian, DE Vaughan Circulation 146 (Suppl_1), A13596-A13596, 2022 | | 2022 |
| Orally active small molecule inhibitor of pai-1 DE Vaughan, JA Levine, T Miyata US Patent App. 17/441,484, 2022 | | 2022 |
| Assessment of virological contributions to COVID-19 outcomes in a longitudinal cohort of hospitalized adults LM Simons, R Lorenzo-Redondo, M Gibson, SL Kinch, JP Vandervaart, ... Open Forum Infectious Diseases 9 (3), ofac027, 2022 | 14 | 2022 |
| Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study Y Zheng, M Habes, M Gonzales, R Pomponio, I Nasrallah, S Khan, ... Aging (Albany NY) 14 (4), 1691, 2022 | 19 | 2022 |
| Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2. 5 AK Ghosh, S Soberanes, E Lux, M Shang, RP Aillon, M Eren, ... Environmental Pollution 287, 117283, 2021 | 11 | 2021 |
| 1600 Assessing Necessity and Cost-Effectiveness of Routine Pre-Thyroidectomy Group and Save Tests S Karim, C Halliday, S Shah, D Vaughan British Journal of Surgery 108 (Supplement_6), znab259. 178, 2021 | | 2021 |
| Identification of cardiac fibrosis in young adults with a homozygous frameshift variant in SERPINE1 SS Khan, SJ Shah, JL Strande, AS Baldridge, P Flevaris, MJ Puckelwartz, ... JAMA cardiology 6 (7), 841-846, 2021 | 10 | 2021 |
| Inhibition of PAI‐1 Promotes Lipolysis and Enhances Weight Loss in Obese Mice JA Levine, S Olivares, T Miyata, DE Vaughan, AS Henkel Obesity 29 (4), 713-720, 2021 | 8 | 2021 |
| Structural insight into the two-step mechanism of PAI-1 inhibition by small molecule TM5484 M Sillen, T Miyata, DE Vaughan, SV Strelkov, PJ Declerck International journal of molecular sciences 22 (3), 1482, 2021 | 18 | 2021 |
| Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells T Yahata, K Hirano, Y Muguruma, K Naka, K Hozumi, DE Vaughan, ... Haematologica 106 (2), 483, 2021 | 22 | 2021 |
