PKA inhibition kills l-asparaginase-resistant leukemic cells from relapsed acute lymphoblastic leukemia patients JK Lee, X Wang, J Wang, JL Rosales, KY Lee Cell Death Discovery 10 (1), 257, 2024 | | 2024 |
PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia H Kamran, JK Lee, KY Lee Frontiers in Cell and Developmental Biology 12, 1388745, 2024 | | 2024 |
Biomarkers and therapeutic strategies in acute lymphoblastic leukemia KY Lee, M Maggi, C Scotti Frontiers in Cell and Developmental Biology 11, 1211569, 2023 | 1 | 2023 |
Requirement for ER-mitochondria Ca2+ transfer, ROS production and mPTP formation in L-asparaginase-induced apoptosis of acute lymphoblastic leukemia cells JK Lee, JL Rosales, KY Lee Frontiers in Cell and Developmental Biology 11, 1124164, 2023 | 3 | 2023 |
Cdk5 regulates IP3R1-mediated Ca2+ dynamics and Ca2+-mediated cell proliferation S NavaneethaKrishnan, V Law, J Lee, JL Rosales, KY Lee Cellular and Molecular Life Sciences 79 (9), 495, 2022 | 5 | 2022 |
ROS-Mediated Apoptosis in Cancer S NavaneethaKrishnan, JL Rosales, KY Lee Handbook of Oxidative Stress in Cancer: Mechanistic Aspects, 599-618, 2022 | | 2022 |
CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway X Wang, P Sipila, Z Si, JL Rosales, X Gao, KY Lee Cell Death & Disease 13 (1), 9, 2021 | 3 | 2021 |
Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A X Wang, JL Rosales, X Gao, KY Lee Biomedicine & Pharmacotherapy 138, 111463, 2021 | 5 | 2021 |
Cdk5 Loss Alters Mitochondrial Cristae Organization SN Krishnan, JL Rosales, KY Lee Journal of Cancer Treatment and Diagnosis 5 (1), 2021 | | 2021 |
D, L-Methadone causes leukemic cell apoptosis via an OPRM1-triggered increase in IP3R-mediated ER Ca2+ release and decrease in Ca2+ efflux, elevating [Ca2+] i JK Lee, JL Rosales, HG Byun, KY Lee Scientific Reports 11 (1), 1009, 2021 | 13 | 2021 |
Loss of Cdk5rap2 triggers cellular senescence via β-catenin-mediated downregulation of WIP1 X Wang, P Sipila, Z Si, JL Rosales, X Gao, KY Lee bioRxiv, 2020.07. 09.194761, 2020 | | 2020 |
Cdk5: A Mediator of Mptp Opening S NavaneethaKrishnan, JL Rosales, KY Lee Journal of Cancer Treatment and Diagnosis 4 (2), 2020 | | 2020 |
mPTP opening caused by Cdk5 loss is due to increased mitochondrial Ca2+ uptake S NavaneethaKrishnan, JL Rosales, KY Lee Oncogene 39 (13), 2797-2806, 2020 | 38 | 2020 |
HAP1 loss confers l-asparaginase resistance in ALL by downregulating the calpain-1-Bid-caspase-3/12 pathway JK Lee, SM Kang, X Wang, JL Rosales, X Gao, HG Byun, Y Jin, S Fu, ... Blood, The Journal of the American Society of Hematology 133 (20), 2222-2232, 2019 | 46 | 2019 |
ROS‐mediated cancer cell killing through dietary phytochemicals S NavaneethaKrishnan, JL Rosales, KY Lee Oxidative medicine and cellular longevity 2019 (1), 9051542, 2019 | 172 | 2019 |
Neutrophil TLR4 and PKR are targets of breast cancer cell glycosaminoglycans and effectors of glycosaminoglycan-induced APRIL secretion U Bat-Erdene, E Quan, K Chan, BM Lee, W Matook, KY Lee, JL Rosales Oncogenesis 7 (6), 45, 2018 | 21 | 2018 |
Targeting Cdk5 for killing of breast cancer cells via perturbation of redox homeostasis S NavaneethaKrishnan, JL Rosales, KY Lee Oncoscience 5 (5-6), 152, 2018 | 15 | 2018 |
Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore S NavaneethaKrishnan, JL Rosales, KY Lee Oncogene 37 (13), 1788-1804, 2018 | 64 | 2018 |
Integration of a bacterial gene sequence into a chronic eosinophilic leukemia patient’s genome as part of a fusion gene linker S Sidhoo, JL Rosales, KY Lee Biomarker Research 5, 1-3, 2017 | 3 | 2017 |
Genome-wide loss-of-function genetic screening identifies opioid receptor μ1 as a key regulator of L-asparaginase resistance in pediatric acute lymphoblastic leukemia SM Kang, JL Rosales, V Meier-Stephenson, S Kim, KY Lee, A Narendran Oncogene 36 (42), 5910-5913, 2017 | 29 | 2017 |