| Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL D Nayak, D Lv, Y Yuan, P Zhang, W Hu, A Nayak, EA Ruben, Z Lv, ... Nature communications 15 (1), 2743, 2024 | 2 | 2024 |
| Abstract 1209 Structural And Biochemical Studies Of Proteolysis-Targeting Chimera (PROTAC) Against Oncogenic Anti-Apoptotic Proteins, BCL-xl And Bcl-2 D Nayak, D Lyu, W Hu, G Zheng, D Zhao, S Olsen Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
| Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer M Afsar, GQ Liu, L Jia, EA Ruben, D Nayak, Z Sayyad, PS Bury, KE Cano, ... Nature communications 14 (1), 4786, 2023 | 5 | 2023 |
| Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase M Zmudzinski, W Rut, K Olech, J Granda, M Giurg, M Burda-Grabowska, ... Scientific reports 13 (1), 9161, 2023 | 47* | 2023 |
| Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease D Nayak, P dos Santos Bury, M Drag, AN Nijkerk, F El Oualid, SK Olsen Deubiquitinases: Methods and Protocols, 171-188, 2022 | 1 | 2022 |
| Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts DJ Strub, M Talma, M Strub, W Rut, M Zmudzinski, W Brud, J Neyts, ... Scientific reports 12 (1), 14230, 2022 | 14 | 2022 |
| Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6 L Yuan, F Gao, Z Lv, D Nayak, A Nayak, P Santos Bury, KE Cano, L Jia, ... Nature communications 13 (1), 4880, 2022 | 7 | 2022 |
| Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy D Nayak, EV Wasmuth, SK Olsen Cell chemical biology 29 (6), 927-929, 2022 | 1 | 2022 |
| Structure of Aedes aegypti procarboxypeptidase B1 and its binding with Dengue virus for controlling infection E Gavor, YK Choong, NK Tulsian, D Nayak, F Idris, H Sivaraman, ... Life Science Alliance 5 (1), 2022 | 2 | 2022 |
| Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity D Lv, P Pal, X Liu, Y Jia, D Thummuri, P Zhang, W Hu, J Pei, Q Zhang, ... Nature communications 12 (1), 6896, 2021 | 91 | 2021 |
| Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... Science advances 6 (42), eabd4596, 2020 | 468* | 2020 |
| Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities in vitro S Singh, J Ng, D Nayak, J Sivaraman Journal of Biological Chemistry 294 (52), 19934-19949, 2019 | 21 | 2019 |
| Structure of ScpC, a virulence protease from Streptococcus pyogenes, reveals the functional domains and maturation mechanism C Jobichen, YC Tan, MT Prabhakar, D Nayak, D Biswas, NS Pannu, ... Biochemical Journal 475 (17), 2847-2860, 2018 | 19 | 2018 |
| Structure of LNX1: Ubc13~ ubiquitin complex reveals the role of additional motifs for the E3 ligase activity of LNX1 D Nayak, J Sivaraman Journal of molecular biology 430 (8), 1173-1188, 2018 | 14 | 2018 |
| A novel encystation specific protein kinase regulates chitin synthesis in Entamoeba invadens SK Samanta, SS Varghese, D Krishnan, M Baidya, D Nayak, S Mukherjee, ... Molecular and biochemical parasitology 220, 19-27, 2018 | 6 | 2018 |
| UBIQUITINATION MECHANISM OF RING TYPE E3 LIGASE LIGAND OF NUMB PROTEIN X AND THEIR STRUCTURAL STUDIES D NAYAK | | 2016 |
| Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination D Nayak, J Sivaraman Oncotarget 6 (33), 34342, 2015 | 25 | 2015 |
| Supplementary Information Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7 … M Zmudzinski, W Rut, K Olech, J Granda, M Giurg, M Burda-Grabowska, ... | | |
