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Christopher J. Halbrook
Christopher J. Halbrook
在 uci.edu 的电子邮件经过验证 - 首页
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Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions
JM Alektiar, M Shan, MD Radyk, L Zhang, CJ Halbrook, L Lin, C Espinoza, ...
Plos one 19 (6), e0303577, 2024
12024
Cancer Hallmarks: Piecing the Puzzle Together
MP Alcolea, D Alonso-Curbelo, C Ambrogio, S Bullman, AL Correia, ...
Cancer Discovery 14 (4), 674-682, 2024
12024
Metabolism as a key regulator of macrophage phenotype in pancreatic cancer
C Anaraki, C Halbrook
Cancer Research 84 (6_Supplement), 1599-1599, 2024
2024
The epigenetic factor BMI1 regulates metabolism and tumorigenesis in human pancreatic cancer cells
JN Mills, D Awad, HK Schofield, JK Thompson, H Watkoske, D Sutton, ...
Cancer Research 84 (6_Supplement), 4441-4441, 2024
2024
Abstract PR10: Uridine-to-ribose axis supports glucose-restricted pancreatic cancer
ZC Nwosu, MH Ward, P Sajjakulnukit, P Poudel, C Ragulan, S Kasperek, ...
Cancer Research 84 (2_Supplement), PR10-PR10, 2024
2024
Abstract C024: Single-cell transcriptomics reveals unique stromal and metabolic heterogeneity in liver metastatic pancreatic cancer
R Singh, N Yousefian, N Steele, C Halbrook
Cancer Research 84 (2_Supplement), C024-C024, 2024
2024
Abstract A056: Targeting the mevalonate biosynthesis pathway in gemcitabine resistant pancreatic cancer
AK Beutel, S Calderon, E Nghiem, R Singh, C Anaraki, K Gulay, H Tiriac, ...
Cancer Research 84 (2_Supplement), A056-A056, 2024
2024
Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung
D Whyte, J Vande Voorde, D Sumpton, S Dhayade, E Dornier, M Moore, ...
bioRxiv, 2024.07. 02.601676, 2024
2024
Glucose-6-phosphate dehydrogenase deficiency accelerates pancreatic acinar-to-ductal metaplasia
MD Radyk, BS Nelson, CJ Halbrook, A Wood, B Lavoie, L Salvatore, ...
bioRxiv, 2023
12023
Uridine-derived ribose fuels glucose-restricted pancreatic cancer
ZC Nwosu, MH Ward, P Sajjakulnukit, P Poudel, C Ragulan, S Kasperek, ...
Nature 618 (7963), 151-158, 2023
452023
Pancreatic cancer: Advances and challenges
CJ Halbrook, CA Lyssiotis, MP di Magliano, A Maitra
Cell 186 (8), 1729-1754, 2023
3082023
Arginase 1 is a key driver of immune suppression in pancreatic cancer
RE Menjivar, ZC Nwosu, W Du, KL Donahue, HS Hong, C Espinoza, ...
Elife 12, e80721, 2023
412023
Barriers and opportunities for gemcitabine in pancreatic cancer therapy
AK Beutel, CJ Halbrook
American Journal of Physiology-Cell Physiology 324 (2), C540-C552, 2023
332023
An Optimized Enzyme-Nucleobase Pair Enables In Vivo RNA Metabolic Labeling with Improved Cell-Specificity
MK Singha, J Zimak, SR Levine, N Dai, C Hong, C Anaraki, M Gupta, ...
Biochemistry 61 (23), 2638-2642, 2022
32022
Differential stress responses drive asparagine exchange in pancreatic cancer.
C Anaraki, G Thurston, NG Steele, SA Kerk, H Hong, P Sajjakulnukit, ...
CANCER RESEARCH 82 (22), 64-65, 2022
2022
Deconvoluting the metastatic PDA tumor microenvironment
R Singh, C Halbrook, N Steele
CANCER RESEARCH 82 (22), 167-168, 2022
2022
Abstract B012: Differential stress responses drive asparagine exchange in pancreatic cancer
C Anaraki, G Thurston, NG Steele, SA Kerk, H Hong, P Sajjakulnukit, ...
Cancer Research 82 (22_Supplement), B012-B012, 2022
2022
Abstract C083: Deconvoluting the metastatic PDA tumor microenvironment
R Singh, C Halbrook, N Steele
Cancer Research 82 (22_Supplement), C083-C083, 2022
2022
Abstract PR023: Targeting gemcitabine resistance in pancreatic cancer
AK Beutel, R Singh, C Anaraki, G Tong, T Martinez, A Kleger, Z Jutric, ...
Cancer Research 82 (22_Supplement), PR023-PR023, 2022
2022
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells
CJ Halbrook, G Thurston, S Boyer, C Anaraki, JA Jiménez, A McCarthy, ...
Nature cancer 3 (11), 1386-1403, 2022
272022
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