关注
Helena Thörn
Helena Thörn
Medical doctor at Sahlgrenska University hospital
在 vgregion.se 的电子邮件经过验证
标题
引用次数
年份
Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption (vol 22, 71, 2020)
J Eriksson, E Sjogren, H Lennernas, H Thorn
AAPS JOURNAL 23 (1), 2021
12021
Correction to: Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption
J Eriksson, E Sjögren, H Lennernäs, H Thörn
The AAPS Journal 23 (1), 2021
2021
Pulmonary drug absorption and systemic exposure in human: Predictions using physiologically based biopharmaceutics modeling
J Eriksson, H Thörn, H Lennernäs, E Sjögren
European Journal of Pharmaceutics and Biopharmaceutics 156, 191-202, 2020
172020
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling …
A Ahmad, X Pepin, L Aarons, Y Wang, AS Darwich, JM Wood, ...
European Journal of Pharmaceutics and Biopharmaceutics 156, 50-63, 2020
282020
Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption
J Eriksson, E Sjögren, H Lennernäs, H Thörn
The AAPS Journal 22, 1-12, 2020
182020
Experimental evidence of regional lung deposition differences effecting the systemic exposure in dog
S Oag, H Thorn, U Tehler
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY 33 (2), A27-A27, 2020
12020
Pulmonary dissolution of poorly soluble compounds studied in an ex vivo rat lung model
J Eriksson, H Thörn, E Sjögren, L Holmstén, K Rubin, H Lennernäs
Molecular Pharmaceutics 16 (7), 3053-3064, 2019
262019
Ranking in vitro dissolution of orally inhaled drug substance powders in a time-efficient manner
F Franek, L Nilsson, H Thörn, R Fransson, U Tehler
J. Aerosol Med. Pulm. Drug Delivery 32, A17, 2019
22019
Ranking in vitro dissolution of inhaled micronized drug powders including a candidate drug with two different particle sizes
F Franek, R Fransson, H Thorn, P Backman, PU Andersson, U Tehler
Molecular pharmaceutics 15 (11), 5319-5326, 2018
302018
Deposition modelling of inhaled aclidinium and budesonide and comparison to gamma scintigraphy measurement
H Thorn, T Loof, G Petersson, F Franek, R Fransson, U Tehler
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2018
22018
Investigation of pulmonary drug permeability and tissue retention by computational analysis of rat ex vivo lung absorption profiles
J Eriksson, E Sjogren, H Thorn, K Rubin, P Backman, H Lennernas
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY 31 (2), A8-A9, 2018
2018
Biorelevant and flexible dose deposition of drug substance powders and nebulised liquids onto filters and cell-cultures
F Franek, G Yousef, KB Sivars, H Thorn, R Fransson, U Tehler
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY 31 (2), A17-A18, 2018
12018
Lung-Sim: a physiologically based biopharmaceutical prediction tool
U Tehler, R Fransson, H Thorn, F Franek, J Westergren
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2018
82018
Pulmonary absorption–estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex vivo rat model and computational analysis
J Eriksson, E Sjögren, H Thörn, K Rubin, P Bäckman, H Lennernäs
European Journal of Pharmaceutics and Biopharmaceutics 124, 1-12, 2018
442018
Reply to “Comment on ‘In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models’”
E Sjögren, H Thörn, C Tannergren
Molecular Pharmaceutics 14 (1), 340-343, 2017
62017
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
A Margolskee, AS Darwich, X Pepin, L Aarons, A Galetin, ...
European Journal of Pharmaceutical Sciences 96, 610-625, 2017
662017
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across …
AS Darwich, A Margolskee, X Pepin, L Aarons, A Galetin, ...
European Journal of Pharmaceutical Sciences 96, 626-642, 2017
482017
In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models
E Sjögren, H Thorn, C Tannergren
Molecular pharmaceutics 13 (6), 1763-1778, 2016
882016
Binding Processes Determine the Stereoselective Intestinal and Hepatic Extraction of Verapamil in Vivo
HA Thörn, E Sjögren, PA Dickinson, H Lennernäs
Molecular Pharmaceutics 9 (11), 3034-3045, 2012
72012
Extensive intestinal glucuronidation of raloxifene in vivo in pigs and impact for oral drug delivery
HA Thörn, M Yasin, PA Dickinson, H Lennernäs
Xenobiotica 42 (9), 917-928, 2012
142012
系统目前无法执行此操作,请稍后再试。
文章 1–20