The modern human aryl hydrocarbon receptor is more active when ancestralized by genome editing N Helmbrecht, M Lackner, T Maricic, S Pääbo Proceedings of the National Academy of Sciences 121 (22), e2402159121, 2024 | | 2024 |
Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development L Xing, V Gkini, AI Nieminen, HC Zhou, M Aquilino, R Naumann, K Reppe, ... Nature Communications 15 (1), 3468, 2024 | 3 | 2024 |
The genetic changes that shaped Neandertals, Denisovans, and modern humans H Zeberg, M Jakobsson, S Pääbo Cell 187 (5), 1047-1058, 2024 | 7 | 2024 |
Efficient high-precision homology-directed repair-dependent genome editing by HDRobust S Riesenberg, P Kanis, D Macak, D Wollny, D Düsterhöft, J Kowalewski, ... Nature methods 20 (9), 1388-1399, 2023 | 15 | 2023 |
Ancient human DNA recovered from a Palaeolithic pendant E Essel, EI Zavala, E Schulz-Kornas, MB Kozlikin, H Fewlass, B Vernot, ... Nature 618 (7964), 328-332, 2023 | 25 | 2023 |
Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals R Ågren, S Patil, X Zhou, K Sahlholm, S Pääbo, H Zeberg Molecular biology and evolution 40 (6), msad130, 2023 | 3 | 2023 |
The occupational history of Denisova Cave EI Zavala, Z Jacobs, B Vernot, MV Shunkov, MB Kozlikin, AP Derevianko, ... Wiley, 2023 | | 2023 |
Detection of unintended on-target effects in CRISPR genome editing by DNA donors carrying diagnostic substitutions M Lackner, N Helmbrecht, S Pääbo, S Riesenberg Nucleic Acids Research 51 (5), e26-e26, 2023 | 4 | 2023 |
Response to comment on “Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals” A Pinson, T Maricic, H Zeberg, S Pääbo, WB Huttner Science 379 (6636), eadf2212, 2023 | 1 | 2023 |
Functional dissection of two amino acid substitutions unique to the human FOXP2 protein U Bornschein, H Zeberg, W Enard, W Hevers, S Pääbo Scientific Reports 13 (1), 3747, 2023 | 3 | 2023 |
The molecular evolution of spermatogenesis across mammals F Murat, N Mbengue, SB Winge, T Trefzer, E Leushkin, M Sepp, ... Nature 613 (7943), 308-316, 2023 | 67 | 2023 |
Genetic insights into the social organization of Neanderthals L Skov, S Peyrégne, D Popli, LNM Iasi, T Devièse, V Slon, EI Zavala, ... Nature 610 (7932), 519-525, 2022 | 64 | 2022 |
Denisovans from Baishiya Karst Cave on the Tibetan Plateau D Zhang, F Welker, CC Shen, B Li, JJ Hublin, S Pääbo, Q Fu, F Chen Insights Into Human History in the Eurasian Stone Age: Recent Developments …, 2022 | | 2022 |
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals A Pinson, L Xing, T Namba, N Kalebic, J Peters, CE Oegema, S Traikov, ... Science 377 (6611), eabl6422, 2022 | 93 | 2022 |
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development F Mora-Bermúdez, P Kanis, D Macak, J Peters, R Naumann, L Xing, ... Science advances 8 (30), eabn7702, 2022 | 34 | 2022 |
The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals S Peyrégne, J Kelso, BM Peter, S Pääbo Elife 11, e75464, 2022 | 15 | 2022 |
High-throughput muscle fiber typing from RNA sequencing data N Oskolkov, M Santel, HM Parikh, O Ekström, GJ Camp, ... Skeletal Muscle 12 (1), 16, 2022 | 7 | 2022 |
The clinically relevant CYP2C8*3 and CYP2C9*2 haplotype is inherited from Neandertals S Haeggström, M Ingelman-Sundberg, S Pääbo, H Zeberg The Pharmacogenomics Journal 22 (4), 247-249, 2022 | 12 | 2022 |
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage S Riesenberg, N Helmbrecht, P Kanis, T Maricic, S Pääbo Nature communications 13 (1), 489, 2022 | 50 | 2022 |
A substitution in the glutathione reductase lowers electron leakage and inflammation in modern humans L Coppo, P Mishra, N Siefert, A Holmgren, S Pääbo, H Zeberg Science Advances 8 (1), eabm1148, 2022 | 8 | 2022 |