Mechanistic modeling as an explanatory tool for clinical treatment of chronic catatonia PD Roberts, J Conour Frontiers in Pharmacology 13, 1025417, 2022 | | 2022 |
AMPA Glutamate Receptor (AMPA Receptor), Conductance Models PD Roberts Encyclopedia of Computational Neuroscience, 175-177, 2022 | 1 | 2022 |
Exploring the relation between BOLD fMRI and cognitive performance using a computer-based quantitative systems pharmacology model: Applications to the COMTVAL158MET genotype … H Geerts, P Roberts, A Spiros European Neuropsychopharmacology 50, 12-22, 2021 | 4 | 2021 |
Impact of amyloid-beta changes on cognitive outcomes in Alzheimer’s disease: analysis of clinical trials using a quantitative systems pharmacology model H Geerts, A Spiros, P Roberts Alzheimer's research & therapy 10, 1-14, 2018 | 30 | 2018 |
P1‐054: REVISITING FAILED CLINICAL TRIALS: APPLICATION OF QUANTITATIVE SYSTEMS PHARMACOLOGY TO THE IMPACT OF COMEDICATIONS, GENOTYPES AND AMYLOID STATUS ON SEROTONIN MODULATORS A Spiros, H Geerts, P Roberts, Computational Neuropharmacology Alzheimer's & Dementia 14 (7S_Part_5), P288-P289, 2018 | | 2018 |
A quantitative systems pharmacology study on optimal scenarios for switching to paliperidone palmitate once-monthly H Geerts, A Spiros, P Roberts, L Alphs Schizophrenia Research 197, 261-268, 2018 | 7 | 2018 |
Towards the virtual human patient. Quantitative Systems Pharmacology in Alzheimer's disease H Geerts, A Spiros, P Roberts, R Carr European journal of pharmacology 817, 38-45, 2017 | 12 | 2017 |
Phosphodiesterase 10 inhibitors in clinical development for CNS disorders H Geerts, A Spiros, P Roberts Expert review of neurotherapeutics 17 (6), 553-560, 2017 | 34 | 2017 |
Semi-mechanistic computer simulation of psychotic symptoms in schizophrenia with a model of a humanized cortico-striatal-thalamocortical loop A Spiros, P Roberts, H Geerts European Neuropsychopharmacology 27 (2), 107-119, 2017 | 8 | 2017 |
Systems pharmacology and pharmacodynamics DE Mager, HHC Kimko Springer, 2016 | 15 | 2016 |
A humanized clinically calibrated quantitative systems pharmacology model for hypokinetic motor symptoms in Parkinson’s disease P Roberts, A Spiros, H Geerts Frontiers in pharmacology 7, 171890, 2016 | 37 | 2016 |
Multi-scale modeling of drug action in the nervous system H Geerts, P Roberts, A Spiros, R Carr Systems Pharmacology and Pharmacodynamics, 305-324, 2016 | 1 | 2016 |
Responses to social vocalizations in the dorsal cochlear nucleus of mice PD Roberts, CV Portfors Frontiers in Systems Neuroscience 9, 172, 2015 | 27 | 2015 |
Assessing the synergy between cholinomimetics and memantine as augmentation therapy in cognitive impairment in schizophrenia. A virtual human patient trial using quantitative … H Geerts, P Roberts, A Spiros Frontiers in pharmacology 6, 198, 2015 | 33 | 2015 |
Understanding responder neurobiology in schizophrenia using a quantitative systems pharmacology model: application to iloperidone H Geerts, P Roberts, A Spiros, S Potkin Journal of Psychopharmacology 29 (4), 372-382, 2015 | 21 | 2015 |
A computer-based quantitative systems pharmacology model of negative symptoms in schizophrenia: exploring glycine modulation of excitation-inhibition balance A Spiros, P Roberts, H Geerts Frontiers in Pharmacology 5, 104616, 2014 | 15 | 2014 |
Memristor Implementation of Neurobiological Design Principles PD Roberts | | 2014 |
Prediction of Efficacy of Vabicaserin, a 5‐HT2C Agonist, for the Treatment of Schizophrenia Using a Quantitative Systems Pharmacology Model J Liu, A Ogden, TA Comery, A Spiros, P Roberts, H Geerts CPT: Pharmacometrics & Systems Pharmacology 3 (4), 1-8, 2014 | 47 | 2014 |
Mismatch of structural and functional tonotopy for natural sounds in the auditory midbrain CV Portfors, PD Roberts Neuroscience 258, 192-203, 2014 | 19 | 2014 |
Synaptic Dynamics: Overview. PD Roberts Encyclopedia of Computational Neuroscience, 2014 | 4 | 2014 |