Hydrophobic tagging-induced degradation of NAMPT in leukemia cells M Guo, YQ Song, J Cheng, G Dong, X Sun, C Sheng Chinese Chemical Letters 35 (9), 109392, 2024 | 1 | 2024 |
Discovery of a potent and selective JAK1-targeting PROTAC degrader with anti-tumor activities X Zhang, W Wang, G Dong, Y Song, X Zhai, C Sheng Bioorganic & Medicinal Chemistry Letters, 129838, 2024 | | 2024 |
Two‐Phase Electrosynthesis of Dihydroxycoumestans: Discovery of a New Scaffold for Topoisomerase I poison YX Chen, S Wu, X Shen, DF Xu, Q Wang, SH Ji, H Zhu, G Wu, C Sheng, ... Chemistry–A European Journal, e202401400, 2024 | | 2024 |
Targeting EFHD2 Inhibits Interferon-γ Signaling and Ameliorates Non-Alcoholic Steatohepatitis JT Fu, J Liu, WB Wu, YT Chen, GD Lu, Q Cao, HB Meng, J Tong, JH Zhu, ... Journal of Hepatology, 2024 | | 2024 |
Design of Evodiamine–Glucose Conjugates with Improved In Vivo Antitumor Activity Z Wu, S Chen, Z Chen, G Dong, D Xu, C Sheng Journal of Medicinal Chemistry 67 (9), 7373-7384, 2024 | | 2024 |
Drugtamer‐PROTAC Conjugation Strategy for Targeted PROTAC Delivery and Synergistic Antitumor Therapy S He, Y Fang, Y Zhu, Z Ma, G Dong, C Sheng Advanced Science, 2401623, 2024 | 1 | 2024 |
Targeting the Undruggables----the Power of Protein Degraders C Zhang, Y Liu, G Li, Z Yang, C Han, X Sun, C Sheng, K Ding, Y Rao Science Bulletin, 2024 | | 2024 |
Inside Back Cover: Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD+ (Angew. Chem. Int. Ed. 12/2024) J Cheng, J Zhang, S He, M Li, G Dong, C Sheng Angewandte Chemie International Edition 63 (12), e202403989, 2024 | | 2024 |
Innenrücktitelbild: Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD+ (Angew. Chem. 12/2024) J Cheng, J Zhang, S He, M Li, G Dong, C Sheng Angewandte Chemie 136 (12), e202403989, 2024 | | 2024 |
Discovery of New Tricyclic Oxime Sampangine Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcosis and Candidiasis W Yang, R Liu, Z Li, J Tu, D Xu, N Liu, C Sheng Journal of Medicinal Chemistry 67 (6), 4726-4738, 2024 | | 2024 |
A combined nanotherapeutic approach targeting farnesoid x receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment J Fu, P Zhang, Z Sun, G Lu, Q Cao, Y Chen, W Wu, J Zhang, C Zhuang, ... Acta Pharmaceutica Sinica B, 2024 | | 2024 |
Discovery of a Potent Nicotinamide Phosphoribosyltransferase Activator for Improving Aging-associated Dysfunctions S Yang, D Sun, Y Wu, S Chen, Y Guo, J Li, G Dong, C Sheng Journal of Medicinal Chemistry, 2024 | | 2024 |
Dual‐Programmable Semiconducting Polymer NanoPROTACs for Deep‐Tissue Sonodynamic‐Ferroptosis Activatable Immunotherapy F Wang, G Dong, M Ding, N Yu, C Sheng, J Li Small 20 (8), 2306378, 2024 | 1 | 2024 |
Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD+ J Cheng, J Zhang, S He, M Li, G Dong, C Sheng Angewandte Chemie, e202315997, 2024 | 1 | 2024 |
Smart glypican-3-targeting peptide–chlorin e6 conjugates for targeted photodynamic therapy of hepatocellular carcinoma Y Fang, H Ma, X Zhang, P Zhang, Y Li, S He, C Sheng, G Dong European Journal of Medicinal Chemistry 264, 116047, 2024 | 1 | 2024 |
Discovery of a new chemical scaffold for the treatment of superbug Candida auris infections J Tu, T Zhu, Q Wang, W Yang, Y Huang, D Xu, N Liu, C Sheng Emerging Microbes & Infections 12 (1), 2208687, 2023 | 4 | 2023 |
Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC) J Bao, Z Chen, Y Li, L Chen, W Wang, C Sheng, G Dong ACS Medicinal Chemistry Letters 15 (1), 29-35, 2023 | 4 | 2023 |
Disseminated Cryptococcosis Involving Skin and Lung in an Immunocompromised Patient After Kidney Transplantation: A Case Report Y Shi, H Zhang, Y Liu, W Fang, Y Xia, J Zhao, G Zhao, C Sheng, Q Zhao, ... Dermatological Health 1 (3), 1-8, 2023 | | 2023 |
A Case Report of Talaromyces marneffei Infection Repeatedly Misdiagnosed as Tuberculosis in an HIV-Negative Patient K Pan, G Zhao, W Fang, C Sheng, Q Zhao, Y He, AJ Chen, W Liao, ... Dermatological Health 1 (3), 9-16, 2023 | | 2023 |
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion Y Fu, Y Huang, C Zhou, X Li, G Dong, M Huang, J Ding, C Sheng Journal of Medicinal Chemistry 66 (24), 16694-16703, 2023 | 2 | 2023 |