| A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer A Szczepanski, N Tsuboyama, H Lyu, P Wang, O Beytullahoglu, T Zhang, ... Nature Communications 15 (1), 2067, 2024 | 3 | 2024 |
| Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment Z Zhao, Y Aoi, CN Philips, KA Meghani, SR Gold, Y Yu, LS John, J Qian, ... Proceedings of the National Academy of Sciences 120 (52), e2310063120, 2023 | 3 | 2023 |
| Use of nucleotide synthesis inhibitors for targeted therapy in mll3/4 compass mutant cancer A Shilatifard, Z Zhao US Patent App. 18/328,011, 2023 | | 2023 |
| Iron drives anabolic metabolism through active histone demethylation and mTORC1 JS Shapiro, HC Chang, Y Tatekoshi, Z Zhao, ZS Waxali, BJ Hong, H Chen, ... Nature Cell Biology 25 (10), 1478-1494, 2023 | 11 | 2023 |
| Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations Z Zhao, K Cao, J Watanabe, CN Philips, JM Zeidner, Y Ishi, Q Wang, ... The Journal of clinical investigation 133 (13), 2023 | 3 | 2023 |
| CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS Z Zhao, EJ Rendleman, AP Szczepanski, MA Morgan, L Wang, ... Science Advances 8 (40), eadd3339, 2022 | 6 | 2022 |
| POU2AF2/C11orf53 functions as a coactivator of POU2F3 by maintaining chromatin accessibility and enhancer activity AP Szczepanski, N Tsuboyama, J Watanabe, R Hashizume, Z Zhao, ... Science Advances 8 (40), eabq2403, 2022 | 36 | 2022 |
| MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer N Tsuboyama, AP Szczepanski, Z Zhao, L Wang Genome biology 23 (1), 206, 2022 | 3 | 2022 |
| Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer N Tsuboyama, R Wang, AP Szczepanski, H Chen, Z Zhao, L Shi, L Wang Oncogene 41 (15), 2152-2162, 2022 | 20 | 2022 |
| The Jumonji-C Histone Lysine Demethylase KDM3B Senses Cellular Iron to Regulate Anabolism Through mTORC1 J Shapiro, HC Chang, Z Zhao, J Geier, E Bartom, C Chen, Y Chen, ... | 1 | 2022 |
| PAX9 determines epigenetic state transition and cell fate in cancer Z Zhao, AP Szczepanski, N Tsuboyama, H Abdala-Valencia, YA Goo, ... Cancer research 81 (18), 4696-4708, 2021 | 12 | 2021 |
| A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells WKM Lai, L Mariani, G Rothschild, ER Smith, BJ Venters, TR Blanda, ... Genome research 31 (9), 1663-1679, 2021 | 13 | 2021 |
| Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors A Shilatifard, Z Zhao US Patent 11,071,727, 2021 | 1 | 2021 |
| Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia L Wang, NW Birch, Z Zhao, CM Nestler, A Kazmer, A Shilati, A Blake, ... Nature Cancer 2 (5), 515-526, 2021 | 45 | 2021 |
| ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer AP Szczepanski, Z Zhao, T Sosnowski, YA Goo, ET Bartom, L Wang Genome medicine 12, 1-20, 2020 | 42 | 2020 |
| A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells WKM Lai, L Mariani, G Rothschild, ER Smith, BJ Venters, TR Blanda, ... bioRxiv, 2020.06. 08.140046, 2020 | 3* | 2020 |
| Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation D Douillet, CC Sze, C Ryan, A Piunti, AP Shah, M Ugarenko, SA Marshall, ... Nature Genetics 52 (6), 615-625, 2020 | 91 | 2020 |
| Epigenetic modifications of histones in cancer Z Zhao, A Shilatifard Genome biology 20, 1-16, 2019 | 459 | 2019 |
| β-Catenin/Tcf7l2–dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer Z Zhao, L Wang, E Bartom, S Marshall, E Rendleman, C Ryan, A Shilati, ... Science Advances 5 (7), eaax0698, 2019 | 38 | 2019 |
| Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia Z Zhao, L Wang, AG Volk, NW Birch, KL Stoltz, ET Bartom, SA Marshall, ... Genes & Development 33 (1-2), 61-74, 2019 | 28 | 2019 |
