| Deciphering the NPM1c epigenetic network in acute myeloid leukemogenesis SB da Gama, V Wingenfeld, M Müller, H Issa, R Bhayadia, JH Klusmann, ... Klinische Pädiatrie 236 (03), 0005, 2024 | | 2024 |
| An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant H Mende, A Khatri, C Lange, SA Poveda-Cuevas, G Tascher, ... Cell Reports 42 (12), 2023 | | 2023 |
| Double trouble: IRAK1/4 inhibitors in AML/MDS HJ Uckelmann, JH Klusmann Blood 142 (11), 945-946, 2023 | | 2023 |
| Exploring the novel function of mutant NPM1 on chromatin HJ Uckelmann, EL Haarer, R Takeda, C Hatton, CW Chen, SA Armstrong Klinische Pädiatrie 235 (03), 0057, 2023 | | 2023 |
| Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia HJ Uckelmann, EL Haarer, R Takeda, EM Wong, C Hatton, C Marinaccio, ... Cancer discovery 13 (3), 746-765, 2023 | 41 | 2023 |
| Mutant NPM1 Is Recruited to MLL Target Genes Via Its Acidic Stretch and Nuclear Export Factor CRM1 and Regulates Oncogenic Transcription in Acute Myeloid Leukemia HJ Uckelmann, EL Haarer, R Takeda, E Wong, C Marinaccio, C Hatton, ... Blood 140 (Supplement 1), 5835-5836, 2022 | | 2022 |
| Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts JM Ellegast, G Alexe, A Hamze, S Lin, HJ Uckelmann, PJ Rauch, ... Cancer discovery 12 (7), 1760-1781, 2022 | 22 | 2022 |
| Abstract LB076: Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts JM Ellegast, G Alexe, A Hamze, S Lin, HJ Uckelmann, PJ Rauch, ... Cancer Research 82 (12_Supplement), LB076-LB076, 2022 | | 2022 |
| A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo UM Demel, R Lutz, S Sujer, Y Demerdash, S Sood, F Grünschläger, ... Blood advances 6 (11), 3513-3528, 2022 | 10 | 2022 |
| S115: MUTANT NPM1 BINDS CHROMATIN AND COOPERATES WITH MLL1 TO REGULATE ONCOGENIC TRANSCRIPTION H Uckelmann, S Armstrong, E Haarer, E Wong, C Hatton, F Perner, ... HemaSphere 6, 16-17, 2022 | | 2022 |
| Antigen presentation safeguards the integrity of the hematopoietic stem cell pool P Hernández-Malmierca, D Vonficht, A Schnell, HJ Uckelmann, ... Cell Stem Cell 29 (5), 760-775. e10, 2022 | 42 | 2022 |
| The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML EB Heikamp, JA Henrich, F Perner, EM Wong, C Hatton, Y Wen, ... Blood, The Journal of the American Society of Hematology 139 (6), 894-906, 2022 | 70 | 2022 |
| Chromatin complexes maintain self-renewal of myeloid progenitors in AML: opportunities for therapeutic intervention HJ Uckelmann, SA Armstrong Stem cell reports 15 (1), 6-12, 2020 | 15 | 2020 |
| Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia HJ Uckelmann, SM Kim, EM Wong, C Hatton, H Giovinazzo, JY Gadrey, ... Science 367 (6477), 586-590, 2020 | 181 | 2020 |
| A menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia AV Krivtsov, K Evans, JY Gadrey, BK Eschle, C Hatton, HJ Uckelmann, ... Cancer cell 36 (6), 660-673. e11, 2019 | 280 | 2019 |
| MLL-Menin inhibition reverses pre-leukemic progenitor self-renewal induced by NPM1 mutations and prevents AML development HJ Uckelmann, SM Kim, NJC Antonissen, AV Krivtsov, C Hatton, ... Blood 132, 546, 2018 | 10 | 2018 |
| Location, location, location: Mutant NPM1c cytoplasmic localization is required to maintain stem cell genes in AML HJ Uckelmann, SA Armstrong, RM Stone Cancer cell 34 (3), 355-357, 2018 | 4 | 2018 |
| VTP50469 is a novel, orally available menin-MLL1 inhibitor effective against MLL-rearranged and NPM1-mutant leukemia AV Krivtsov, BK Eschle, M Witkin, JY Gadrey, HJ Uckelmann, S Kitajima, ... Cancer Research 78 (13_Supplement), 4958-4958, 2018 | 1 | 2018 |
| Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4 H Uckelmann, S Blaszkiewicz, C Nicolae, S Haas, A Schnell, S Wurzer, ... Journal of experimental medicine 213 (10), 1961-1971, 2016 | 35 | 2016 |
| Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ... Cell stem cell 17 (4), 422-434, 2015 | 451 | 2015 |
