Inhibition of N‐myristoyltransferase activity promotes androgen receptor degradation in prostate cancer OA Alsaidan, E Onobun, C Ye, L Lou, Z Beharry, ZR Xie, I Lebedyeva, ... The Prostate 84 (3), 254-268, 2024 | | 2024 |
Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models X Li, Y Chen, L Bai, R Zhao, Y Wu, ZR Xie, JM Wu, NJ Bowen, A Danaher, ... British Journal of Cancer 129 (5), 884-894, 2023 | 2 | 2023 |
Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis S Jordan, B Li, E Traore, Y Wu, R Usai, A Liu, ZR Xie, Y Wang Journal of Biological Chemistry 299 (8), 2023 | 2 | 2023 |
A novel Skp1 inhibitor has potent preclinical efficacy against metastatic castration-resistant prostate cancer X Li, K Mamouni, R Zhao, Y Wu, ZR Xie, G Sautto, D Liu, N Bowen, ... Cancer Research 83 (7_Supplement), 519-519, 2023 | | 2023 |
Identifying Drug Candidates for COVID-19 with Large-Scale Drug Screening Y Wu, SD Pegan, D Crich, L Lou, LN Mullininx, EB Starling, C Booth, ... International journal of molecular sciences 24 (5), 4397, 2023 | 1 | 2023 |
Exploring and engineering PAM-diverse Streptococci Cas9 for PAM-directed bifunctional and titratable gene control in bacteria J Wang, Y Teng, X Gong, J Zhang, Y Wu, L Lou, M Li, ZR Xie, Y Yan Metabolic Engineering 75, 68-77, 2023 | 7 | 2023 |
Repositioning nicardipine as a novel targeted therapy for chemoresistant prostate cancer X Li, A Danaher, JM Wu, Y Wu, ZR Xie, N Cook, N Bowen, D Wu Cancer Research 82 (12_Supplement), 5365-5365, 2022 | | 2022 |
Encapsulating Cas9 into extracellular vesicles by protein myristoylation JA Whitley, S Kim, L Lou, C Ye, OA Alsaidan, E Sulejmani, J Cai, ... Journal of extracellular vesicles 11 (4), e12196, 2022 | 28 | 2022 |
DeepFlu: a deep learning approach for forecasting symptomatic influenza A infection based on pre-exposure gene expression A Zan, ZR Xie, YC Hsu, YH Chen, TH Lin, YS Chang, KY Chang Computer Methods and Programs in Biomedicine 213, 106495, 2022 | 9 | 2022 |
Polyphenols as Potential Inhibitors of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp) Y Wu, D Crich, SD Pegan, L Lou, MC Hansen, C Booth, E Desrochers, ... Molecules 26 (24), 7438, 2021 | 12 | 2021 |
Engineering a PAM-flexible SpdCas9 variant as a universal gene repressor J Wang, Y Teng, R Zhang, Y Wu, L Lou, Y Zou, M Li, ZR Xie, Y Yan Nature communications 12 (1), 6916, 2021 | 20 | 2021 |
Polyphenols as alternative treatments of COVID-19 Y Wu, SD Pegan, D Crich, E Desrochers, EB Starling, MC Hansen, ... Computational and structural biotechnology journal 19, 5371-5380, 2021 | 11 | 2021 |
DeepDISE: DNA Binding Site Prediction Using a Deep Learning Method SG Hendrix, KY Chang, Z Ryu, ZR Xie International journal of molecular sciences 22 (11), 5510, 2021 | 8 | 2021 |
Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer X Li, L Gera, S Zhang, Y Chen, L Lou, LM Wilson, ZR Xie, G Sautto, D Liu, ... Theranostics 11 (14), 6873, 2021 | 23 | 2021 |
Structural and functional enrichment analyses for antimicrobial peptides SC Lo, ZR Xie, KY Chang International Journal of Molecular Sciences 21 (22), 8783, 2020 | 9 | 2020 |
Elucidating the inhibitory effect of resveratrol and its structural analogs on selected nucleotide-related enzymes Y Wu, T Hsieh, JM Wu, X Wang, JS Christopher, AH Pham, JDL Swaby, ... Biomolecules 10 (9), 1223, 2020 | 13 | 2020 |
Abstract MP47: Genome-wide Gene-leptin Interaction Study Identifies Loci Contributing to Leptin Resistance L Shen, R Zhang, J Cordero, JS Wang, Y Shen, L Lou, ZR Xie, H Yin, Y Qi, ... Circulation 141 (Suppl_1), AMP47-AMP47, 2020 | | 2020 |
A pilot study of all-computational drug design protocol–from structure prediction to interaction analysis Y Wu, L Lou, ZR Xie Frontiers in Chemistry 8, 81, 2020 | 15 | 2020 |
In silico identification of drug candidates against COVID-19 Y Wu, KY Chang, L Lou, LG Edwards, BK Doma, ZR Xie Informatics in Medicine Unlocked 21, 100461, 2020 | 22 | 2020 |
Nicotinic Acetylcholine Receptor Genes Contribute to Leptin Resistance C Li, L Shen, R Zhang, JS Wang, Y Shen, J Cordero, ZR Xie, L Loou, ... Hypertension 74 (Suppl_1), A139-A139, 2019 | | 2019 |