| Pooled genetic screens to identify vulnerabilities in TERT-promoter-mutant glioblastoma KJ Tu, CE Stewart, PG Hendrickson, JA Regal, SY Kim, DM Ashley, ... Oncogene 42 (44), 3274-3286, 2023 | 2 | 2023 |
| A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer KE Ware, BC Thomas, PD Olawuni, MU Sheth, N Hawkey, M Yeshwanth, ... Frontiers in Molecular Biosciences 10, 1104505, 2023 | 4 | 2023 |
| Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition DL Dayanidhi, JA Somarelli, JB Mantyh, G Rupprecht, RS Roghani, ... Frontiers in Medicine 9, 999004, 2022 | 2 | 2022 |
| The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction SC Walsh, JR Reitano, MS Dickinson, M Kutsch, D Hernandez, ... Cell host & microbe 30 (12), 1671-1684. e9, 2022 | 25 | 2022 |
| Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis BM Lane, M Chryst-Stangl, G Wu, M Shalaby, S El Desoky, CC Middleton, ... JCI insight 7 (2), 2022 | 15 | 2022 |
| Orthogonal genome-wide screens of bat cells identify MTHFD1 as a target of broad antiviral therapy DE Anderson, J Cui, Q Ye, B Huang, Y Tan, C Jiang, W Zu, J Gong, W Liu, ... Proceedings of the National Academy of Sciences 118 (39), e2104759118, 2021 | 32 | 2021 |
| Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer E Altunel, RS Roghani, KY Chen, SY Kim, S McCall, KE Ware, X Shen, ... BMC cancer 20, 1-10, 2020 | 15 | 2020 |
| A comparative oncology drug discovery pipeline to identify and validate new treatments for osteosarcoma JA Somarelli, G Rupprecht, E Altunel, EM Flamant, S Rao, D Sivaraj, ... Cancers 12 (11), 3335, 2020 | 15 | 2020 |
| A precision medicine drug discovery pipeline to identify dual CDK2/9 inhibition as a novel treatment for colorectal cancer. R Salman Roghani, A Sanjari moghaddam, G Rupprecht, E Altunel, ... Journal of Clinical Oncology 38 (15_suppl), e16056-e16056, 2020 | 1 | 2020 |
| From the clinic to the bench and back again in one dog year: how a cross-species pipeline to identify new treatments for sarcoma illuminates the path forward in precision medicine SR Rao, JA Somarelli, E Altunel, LE Selmic, M Byrum, MU Sheth, ... Frontiers in oncology 10, 117, 2020 | 21 | 2020 |
| Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D J Huang, M Chen, ES Xu, L Luo, Y Ma, W Huang, W Floyd, TS Klann, ... Scientific reports 9 (1), 17220, 2019 | 5 | 2019 |
| The whole-genome landscape of Burkitt lymphoma subtypes RI Panea, CL Love, JR Shingleton, A Reddy, JA Bailey, AM Moormann, ... Blood, The Journal of the American Society of Hematology 134 (19), 1598-1607, 2019 | 149 | 2019 |
| Identification of novel mast cell activators using cell-based high-throughput screening HW Choi, C Chan, ID Shterev, HE Lynch, TJ Robinette, ... SLAS DISCOVERY: Advancing Life Sciences R&D 24 (6), 628-640, 2019 | 9 | 2019 |
| Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae DE Anderson, K Pfeffermann, SY Kim, B Sawatsky, J Pearson, M Kovtun, ... MBio 10 (3), 10.1128/mbio. 00826-19, 2019 | 24 | 2019 |
| An integrative systems biology and experimental approach identifies convergence of epithelial plasticity, metabolism, and autophagy to promote chemoresistance S Xu, KE Ware, Y Ding, SY Kim, MU Sheth, S Rao, W Chan, AJ Armstrong, ... Journal of Clinical Medicine 8 (2), 205, 2019 | 18 | 2019 |
| From the clinic to the bench and back again in one dog year: identifying new treatments for sarcoma using a cross-species personalized medicine pipeline S Rao, JA Somarelli, E Altunel, LE Selmic, M Byrum, MU Sheth, S Cheng, ... bioRxiv, 517086, 2019 | | 2019 |
| bcSeq: an R package for fast sequence mapping in high-throughput shRNA and CRISPR screens J Lin, J Gresham, T Wang, SY Kim, J Alvarez, JS Damrauer, S Floyd, ... Bioinformatics 34 (20), 3581-3583, 2018 | 5 | 2018 |
| A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor T Abaffy, JR Bain, MJ Muehlbauer, I Spasojevic, S Lodha, E Bruguera, ... Frontiers in Oncology 8, 162, 2018 | 42 | 2018 |
| A precision medicine strategy to identify the FGFR pathway as a novel target in colorectal cancer liver metastasis. E Altunel, J Somarelli, SY Kim, W Glover, G Rupprecht, SD Hsu Journal of Clinical Oncology 36 (4_suppl), 660-660, 2018 | | 2018 |
| Genetic and functional drivers of diffuse large B cell lymphoma A Reddy, J Zhang, NS Davis, AB Moffitt, CL Love, A Waldrop, S Leppa, ... Cell 171 (2), 481-494. e15, 2017 | 1017 | 2017 |
