| Next-generation DYRK1A inhibitors as a new therapeutic approach for the treatment of hematological malignancies MC Jarvis, G Mittapalli, E Creger, C Nora, M Ibanez, D Bhat, B Hofilena, ... Cancer Research 83 (7_Supplement), 5019-5019, 2023 | 2 | 2023 |
| The pan-CLK/DYRK inhibitor cirtuvivint selectively disrupts alternative splicing and has broad anti-tumor activity in preclinical models EA McMillan, C Bossard, E Creger, C Merkwirth, R Pippa, M Jarvis, ... Cancer Research 82 (12_Supplement), 3928-3928, 2022 | | 2022 |
| Snail acetylation by autophagy‐derived acetyl‐coenzyme A promotes invasion and metastasis of KRAS‐LKB1 co‐mutated lung cancer cells JH Han, YK Kim, H Kim, J Lee, MJ Oh, SB Kim, M Kim, KH Kim, HJ Yoon, ... Cancer Communications, 2022 | 17 | 2022 |
| Abstract P242: Preclinical efficacy landscape of the pan-CLK/DYRK inhibitor Cirtuvivint (SM08502) C Bossard, E Creger, EA McMillan, C Merkwirth, M Ibanez, D Bhat, ... Molecular Cancer Therapeutics 20 (12_Supplement), P242-P242, 2021 | 1 | 2021 |
| Abstract P250: Evaluation of systemic pan-CLK/DYRK inhibition on organ function and tissue self-renewal H Falahatpisheh, M Dehghani, J Morrow, C Tsao, S Dorrow, J Stewart, ... Molecular Cancer Therapeutics 20 (12 Supplement), P250-P250, 2021 | | 2021 |
| Abstract P231: Multigenomic characterization of context-dependent alternative splicing in normal and neoplastic cells EA McMillan, K Sriram, E Creger, C Merkwirth, R Pippa, M Pedraza, L Do, ... Molecular Cancer Therapeutics 20 (12 Supplement), P231-P231, 2021 | | 2021 |
| The Pan-Clk/Dyrk Inhibitor Cirtuvivint (SM08502) Exposes Mechanistic Underpinnings of Alternative Splicing As a Therapeutic Vulnerability in Heme Malignancies C Bossard, EA McMillan, E Creger, B Eastman, CC Mak, DM Beaupre, ... Blood 138, 2950, 2021 | 2 | 2021 |
| Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor K Freeman-Cook, RL Hoffman, N Miller, J Almaden, J Chionis, Q Zhang, ... Cancer Cell 39 (10), 1404-1421. e11, 2021 | 94 | 2021 |
| Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer A Zaman, X Wu, A Lemoff, S Yadavalli, J Lee, C Wang, J Cooper, ... Cell Reports 36 (5), 109491, 2021 | 13 | 2021 |
| Initial results from a Phase 1 trial of a first-in-class pan-CDC-like kinase inhibitor (SM08502) with proof of mechanism in subjects with advanced solid tumors. A Tolcher, HM Babiker, V Chung, E Kim, J Moser, R Karim, A Vandross, ... CANCER RESEARCH 81 (13), 2021 | | 2021 |
| Abstract CT112: Initial results from a Phase 1 trial of a first-in-class pan-CDC-like kinase inhibitor (SM08502) with proof of mechanism in subjects with advanced solid tumors A Tolcher, HM Babiker, V Chung, E Kim, J Moser, R Karim, A Vandross, ... Cancer Research 81 (13_Supplement), CT112-CT112, 2021 | 3 | 2021 |
| A gene expression high-throughput screen (GE-HTS) for coordinated detection of functionally similar effectors in cancer C Rao, DH Huisman, HM Vieira, DE Frodyma, BK Neilsen, B Chakraborty, ... Cancers 12 (11), 3143, 2020 | 12 | 2020 |
| Novel tfeb pathway agonists for metabolic diseases and ageing J Gao, MA White, W Chensu, Y Li, B Posner, G Huang US Patent App. 16/763,518, 2020 | | 2020 |
| An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis SK Hight, A Mootz, RK Kollipara, E McMillan, P Yenerall, Y Otaki, LS Li, ... Neoplasia 22 (8), 294-310, 2020 | 27 | 2020 |
| High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen BK Neilsen, DL Kelly, B Chakraborty, HS Kim, MA White, RE Lewis, ... Scientific data 7 (1), 1-9, 2020 | 5 | 2020 |
| Metabolic diversity in human non-small cell lung cancer cells PH Chen, L Cai, K Huffman, C Yang, J Kim, B Faubert, L Boroughs, B Ko, ... Molecular cell 76 (5), 838-851. e5, 2019 | 141 | 2019 |
| A genome-wide functional signature ontology map and applications to natural product mechanism of action discovery EA McMillan, G Kwon, JR Clemenceau, KW Fisher, RM Vaden, AF Shaikh, ... Cell chemical biology 26 (10), 1380-1392. e6, 2019 | 7 | 2019 |
| Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis M Bansal, J He, M Peyton, M Kustagi, A Iyer, M Comb, M White, JD Minna, ... PloS one 14 (1), e0208646, 2019 | 5 | 2019 |
| High-throughput functional annotation of natural products by integrated activity profiling SK Hight, KL Kurita, EA McMillan, W Bray, TN Clark, AF Shaikh, ... bioRxiv, 748129, 2019 | 10 | 2019 |
| SPARC inhibits metabolic plasticity in ovarian cancer C Naczki, B John, C Patel, A Lafferty, A Ghoneum, H Afify, M White, ... Cancers 10 (10), 385, 2018 | 24 | 2018 |
