Targeting the smooth muscle cell KEAP1-Nrf2-STING axis with pterostilbene attenuates abdominal aortic aneurysm J Zou, Z Zheng, W Ye, M Jin, P Yang, PJ Little, J Wang, Z Liu Phytomedicine 130, 155696, 2024 | | 2024 |
The cytoplasmic sensor, the AIM2 inflammasome: A precise therapeutic target in vascular and metabolic diseases J Lin, J Wang, J Fang, M Li, S Xu, PJ Little, D Zhang, Z Liu British Journal of Pharmacology 181 (12), 1695-1719, 2024 | | 2024 |
The natural polyphenol fisetin in atherosclerosis prevention: a mechanistic review W Yu, Y Zhao, I Ilyas, L Wang, PJ Little, S Xu Journal of Pharmacy and Pharmacology, rgae053, 2024 | | 2024 |
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway X Ni, X Feng, Z Wang, Y Zhang, PJ Little, Y Cao, S Xu, L Tang, J Weng Acta Pharmacologica Sinica, 1-14, 2024 | | 2024 |
Kaempferol and atherosclerosis: From mechanism to medicine M Chen, J Xiao, HR El-Seedi, KS Woźniak, M Daglia, PJ Little, J Weng, ... Critical Reviews in Food Science and Nutrition 64 (8), 2157-2175, 2024 | 20 | 2024 |
A novel mouse model of familial combined hyperlipidemia and atherosclerosis M Chen, Y Xu, L Sun, Z Wang, PJ Little, L Wang, X Xian, J Weng, S Xu Acta Pharmacologica Sinica, 1-5, 2024 | | 2024 |
Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway T Zhang, M Zhu, J Ma, Z Liu, Z Zhang, M Chen, Y Zhao, H Li, S Wang, ... Journal of Advanced Research, 2024 | | 2024 |
Transforming growth factor-β receptors: versatile mechanisms of ligand activation ZJ Chia, Y Cao, PJ Little, D Kamato Acta Pharmacologica Sinica, 1-12, 2024 | 1 | 2024 |
A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection H Jiang, Y Zhao, M Su, L Sun, M Chen, Z Zhang, I Ilyas, Z Wang, PJ Little, ... Pharmacological Research 199, 107029, 2024 | 2 | 2024 |
Animal models of heart failure with preserved ejection fraction (HFpEF): from metabolic pathobiology to drug discovery S Gao, X Liu, T Li, L Chen, Y Feng, Y Wang, Y Yin, PJ Little, X Wu, S Xu, ... Acta Pharmacologica Sinica 45 (1), 23-35, 2024 | 4 | 2024 |
Anti-atherosclerotic effects and molecular targets of ginkgolide B from Ginkgo biloba W Ye, J Wang, PJ Little, J Zou, Z Zheng, J Lu, Y Yin, H Liu, D Zhang, P Liu, ... Acta Pharmaceutica Sinica B, 2023 | 6 | 2023 |
Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes D Kamato, PJ Little Lipoproteins in Diabetes Mellitus, 319-336, 2023 | | 2023 |
Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes A Bobik, N Cohen, AJ Jenkins, T Kyaw, D Sullivan, X Wu, XY Yu, PJ Little Lipoproteins in Diabetes Mellitus, 821-878, 2023 | | 2023 |
Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies X Wu, M Xu, M Geng, S Chen, PJ Little, S Xu, J Weng Signal transduction and targeted therapy 8 (1), 220, 2023 | 30 | 2023 |
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice P Jiang, Z Liu, T Fang, Z Zhang, Y Zhang, D Wang, PJ Little, S Xu, J Weng Basic & Clinical Pharmacology & Toxicology 132 (4), 341-351, 2023 | | 2023 |
Mechanistic insight: linking cardiovascular complications of inflammatory bowel disease H Kumarapperuma, R Wang, PJ Little, D Kamato Trends in Cardiovascular Medicine, 2023 | 7 | 2023 |
Poly (succinimide) nanoparticles as reservoirs for spontaneous and sustained synthesis of poly (aspartic acid) under physiological conditions: potential for vascular … H Adelnia, I Blakey, PJ Little, HT Ta Journal of Materials Chemistry B 11 (12), 2650-2662, 2023 | 9 | 2023 |
Gαq is the specific mediator of PAR-1 transactivation of kinase receptors in vascular smooth muscle cells D Kamato, M Gabr, H Kumarapperuma, ZJ Chia, W Zheng, S Xu, ... International Journal of Molecular Sciences 23 (22), 14425, 2022 | 1 | 2022 |
Mouse models of atherosclerosis in translational research I Ilyas, PJ Little, Z Liu, Y Xu, D Kamato, BC Berk, J Weng, S Xu Trends in Pharmacological Sciences 43 (11), 920-939, 2022 | 37 | 2022 |
Non-mouse models of atherosclerosis: approaches to exploring the translational potential of new therapies D Kamato, I Ilyas, S Xu, PJ Little International Journal of Molecular Sciences 23 (21), 12964, 2022 | 5 | 2022 |