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Luca Freschi
Luca Freschi
Research fellow, Department of Biomedical informatics, Harvard University
在 hms.harvard.edu 的电子邮件经过验证
标题
引用次数
年份
Drug resistance and epidemiological success of modern Mycobacterium tuberculosis lineages in western India
A Dixit, Y Ektefaie, A Kagal, L Freschi, R Karyakarte, R Lokhande, ...
The Journal of Infectious Diseases, jiae240, 2024
2024
Estimation of country-specific tuberculosis resistance antibiograms using pathogen genomics and machine learning
A Dixit, L Freschi, R Vargas, MI Gröschel, M Nakhoul, S Tahseen, ...
BMJ Global Health 9 (3), e013532, 2024
12024
Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex
R Vargas Jr, MJ Luna, L Freschi, M Marin, R Froom, KC Murphy, ...
Proceedings of the National Academy of Sciences 120 (28), e2301394120, 2023
72023
Analysis of Genome-Wide Mutational Dependence in Naturally Evolving Mycobacterium tuberculosis Populations
AG Green, R Vargas Jr, MG Marin, L Freschi, J Xie, MR Farhat
Molecular Biology and Evolution 40 (6), msad131, 2023
32023
Phenotypic and genomic analysis of a large-scale Corynebacterium diphtheriae outbreak among migrant populations in Europe
A Hoefer, HMB Seth-Smith, F Palma, S Schindler, L Freschi, A Dangel, ...
medRxiv, 2023.11. 10.23297228, 2023
12023
A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis
AG Green, CH Yoon, ML Chen, Y Ektefaie, M Fina, L Freschi, MI Gröschel, ...
Nature communications 13 (1), 3817, 2022
282022
The discovery of genome-wide mutational dependence in naturally evolving populations
AG Green, R Vargas Jr, MG Marin, L Freschi, J Xie, MR Farhat
bioRxiv, 2022.06. 24.497504, 2022
12022
Draft Genome Sequences of Two Clostridium botulinum Group II Strains Carrying Phage-Like Plasmids
B Cadieux, OU Lawal, JG Emond-Rheault, J Jeukens, L Freschi, ...
Microbiology Resource Announcements 11 (6), e00091-22, 2022
2022
Modern lineages of Mycobacterium tuberculosis were recently introduced in western India and demonstrate increased transmissibility
A Dixit, A Kagal, Y Ektefaie, L Freschi, R Karyakarte, R Lokhande, ...
medRxiv, 2022.01. 04.22268645, 2022
12022
GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning
MI Gröschel, M Owens, L Freschi, R Vargas, MG Marin, J Phelan, Z Iqbal, ...
Genome medicine 13, 1-14, 2021
342021
1397. Modern Lineages of Mycobacterium tuberculosis Were Recently Introduced in Western India and Demonstrate Increased Transmissibility
A Dixit, A Kagal, Y Ektefaie, L Freschi, R Lokhande, M Groeschel, ...
Open Forum Infectious Diseases 8 (Supplement_1), S783-S784, 2021
2021
Population structure, biogeography and transmissibility of Mycobacterium tuberculosis
L Freschi, R Vargas Jr, A Husain, SMM Kamal, A Skrahina, S Tahseen, ...
Nature communications 12 (1), 6099, 2021
852021
Role of epistasis in amikacin, kanamycin, bedaquiline, and clofazimine resistance in Mycobacterium tuberculosis complex
R Vargas Jr, L Freschi, A Spitaleri, S Tahseen, I Barilar, S Niemann, ...
Antimicrobial Agents and Chemotherapy 65 (11), 10.1128/aac. 01164-21, 2021
512021
Estimation of country-specific tuberculosis antibiograms using genomic data
A Dixit, L Freschi, R Vargas Jr, MI Groeschel, S Tahseen, SMM Alam, ...
medRxiv, 2021.09. 23.21263991, 2021
22021
Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain
MP Moore, IL Lamont, D Williams, S Paterson, I Kukavica-Ibrulj, ...
Microbial genomics 7 (3), 000511, 2021
222021
Globally diverse Mycobacterium tuberculosis resistance acquisition: a retrospective geographical and temporal analysis of whole genome sequences
Y Ektefaie, A Dixit, L Freschi, MR Farhat
The Lancet Microbe 2 (3), e96-e104, 2021
392021
In-host population dynamics of Mycobacterium tuberculosis complex during active disease
R Vargas, L Freschi, M Marin, LE Epperson, M Smith, I Oussenko, ...
Elife 10, e61805, 2021
362021
1653. Estimation of country-specific tuberculosis antibiograms using a wide and deep neural net on a large genomic dataset
A Dixit, L Freschi, R Vargas Jr, M Groeschel, M Chen, S Tahseen, ...
Open Forum Infectious Diseases 7 (Suppl 1), S815, 2020
2020
Contributions from the 2019 literature on bioinformatics and translational informatics
M Smaïl-Tabbone, B Rance
Yearbook of Medical Informatics 29 (01), 188-192, 2020
42020
The Salmonella enterica Plasmidome as a Reservoir of Antibiotic Resistance
JG Emond-Rheault, J Hamel, J Jeukens, L Freschi, I Kukavica-Ibrulj, ...
Microorganisms 8 (7), 1016, 2020
272020
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