A protein kinase C α and β inhibitor blunts hyperphagia to halt renal function decline and reduces adiposity in a rat model of obesity-driven type 2 diabetes J Wang, A Casimiro-Garcia, BG Johnson, J Duffen, M Cain, L Savary, ... Scientific Reports 13 (1), 16919, 2023 | | 2023 |
The type i interferon signature reflects multiple phenotypic and activity measures in dermatomyositis MM Tabata, LM Hodgkinson, TT Wu, S Li, C Huard, S Zhao, D Bennett, ... Arthritis & Rheumatology 75 (10), 1842-1849, 2023 | 11 | 2023 |
Heterogeneity of human intestinal intraepithelial T cells and their abnormal distribution in Crohn’s disease revealed at high resolution N Jaeger, R Gamini, M Cella, JL Schettini, M Bugatti, S Zhao, ... The Journal of Immunology 206 (1_Supplement), 17.02-17.02, 2021 | | 2021 |
Single-cell analyses of Crohn’s disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions N Jaeger, R Gamini, M Cella, JL Schettini, M Bugatti, S Zhao, ... Nature communications 12 (1), 1921, 2021 | 136 | 2021 |
AB015. Skin disease activity and autoantibody phenotype are major determinants of blood interferon signatures in dermatomyositis M Tabata, K Sarin, N Marukian, K Page, C Huard, S Zhao, D Bennett, ... Annals of Translational Medicine 9 (5), 2021 | | 2021 |
RNA Sequencing to Explore Dominant Isoform Switch During CCR6+ Memory T Cell Activation S Zhao, A Barron, K Dower | | 2021 |
QuickIsoSeq for Isoform Quantification in Large-Scale RNA Sequencing R Gamini, R Nakashima, W He, C Zhang, Y Huang, Y Zhang, B Zhang, ... RNA Bioinformatics, 135-145, 2021 | 2 | 2021 |
Pharmacologic inhibition of Protein Kinase C α and Protein Kinase C β halts renal function decline indirectly, by blunting hyperphagia, and directly reduces adiposity in the … J Wang, A Casimiro-Garcia, BG Johnson, J Duffen, M Cain, L Savary, ... bioRxiv, 2020.12. 02.406892, 2020 | | 2020 |
Standard machine learning approaches outperform deep representation learning on phenotype prediction from transcriptomics data AM Smith, JR Walsh, J Long, CB Davis, P Henstock, MR Hodge, ... BMC bioinformatics 21, 1-18, 2020 | 69 | 2020 |
Misuse of RPKM or TPM normalization when comparing across samples and sequencing protocols S Zhao, Z Ye, R Stanton Rna 26 (8), 903-909, 2020 | 327 | 2020 |
Aiolos and T-bet cooperate to repress the ILC3 transcriptional program in human innate lymphocytes CS da Silva, M Cella, R Gamini, P Collins, S Zhao, V Peng, M Robinette, ... The Journal of Immunology 204 (1_Supplement), 84.9-84.9, 2020 | | 2020 |
Skin Disease Activity and Autoantibody Phenotype Are Major Determinants of Blood Interferon Signatures in Dermatomyositis M Tabata, K Sarin, K Page, C Huard, S Zhao, D Bennett, J Johnson, ... ARTHRITIS & RHEUMATOLOGY 71, 2019 | | 2019 |
Subsets of ILC3− ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues M Cella, R Gamini, C Sécca, PL Collins, S Zhao, V Peng, ML Robinette, ... Nature immunology 20 (8), 980-991, 2019 | 188 | 2019 |
THU0033 RNA PROFILING OF HEALTHY AND RHEUMATOID ARTHRITIS SUBJECTS TREATED WITH TOFACITINIB MONOTHERAPY A Hadjipanayis, X Chen, J Lee, S Zhao, W Zhang, D Martin, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 284-284, 2019 | | 2019 |
Applications of machine learning in drug discovery and development J Vamathevan, D Clark, P Czodrowski, I Dunham, E Ferran, G Lee, B Li, ... Nature reviews Drug discovery 18 (6), 463-477, 2019 | 2184 | 2019 |
Alternative splicing, RNA-seq and drug discovery S Zhao Drug discovery today 24 (6), 1258-1267, 2019 | 77 | 2019 |
Molecular profiling of ulcerative colitis subjects from the TURANDOT trial reveals novel pharmacodynamic/efficacy biomarkers H Zhou, L Xi, D Ziemek, S O’Neil, J Lee, Z Stewart, Y Zhan, S Zhao, ... Journal of Crohn's and Colitis 13 (6), 702-713, 2019 | 20 | 2019 |
Deep learning of representations for transcriptomics-based phenotype prediction AM Smith, JR Walsh, J Long, CB Davis, P Henstock, MR Hodge, ... BioRxiv, 574723, 2019 | 8 | 2019 |
canvasDesigner: a versatile interactive high-resolution scientific multi-panel visualization toolkit B Zhang, S Zhao, I Neuhaus Bioinformatics 34 (19), 3419-3420, 2018 | 8 | 2018 |
Computational identification and validation of alternative splicing in ZSF1 rat RNA-seq data, a preclinical model for type 2 diabetic nephropathy C Zhang, K Dower, B Zhang, RV Martinez, LL Lin, S Zhao Scientific reports 8 (1), 7624, 2018 | 12 | 2018 |