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Matthew Wright
Matthew Wright
Executive Director, Genentech
在 gene.com 的电子邮件经过验证
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引用次数
年份
Quantitative characterization of the effects of fulvestrant alone or in combination with taselisib (PI3Kinase inhibitor) on longitudinal tumor growth in patients with estrogen …
A Moein, JY Jin, MR Wright, H Wong
Cancer Chemotherapy and Pharmacology, 1-16, 2024
2024
Retrospective Assessment of Translational Pharmacokinetic–Pharmacodynamic Modeling Performance: A Case Study with Apitolisib, a Dual PI3K/mTOR Inhibitor
A Moein, JY Jin, MR Wright, B Alicke, H Wong
Drugs in R&D, 1-13, 2024
2024
GDC-0214 Is a Potent Inhaled JAK Inhibitor With Efficacy in Multiple Pre-clinical Models of Th2 Inflammation: A Perspective on Use of In Vivo Rodent Models for Early Phase Drug …
C Rinderknecht Eller, H Rardin, N Sambamurthy, C Thadani, X Wu, J Liu, ...
B71. ASTHMA PATHOGENESIS: MORE THAN MEETS THE EYE, A4342-A4342, 2024
2024
Quantitative Assessment of Drug Efficacy and Emergence of Resistance in Patients with Metastatic Renal Cell Carcinoma Using a Longitudinal Exposure‐Tumor Growth Inhibition …
A Moein, JY Jin, MR Wright, H Wong
The Journal of Clinical Pharmacology, 2024
22024
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design
JJ Crawford, J Feng, HD Brightbill, AR Johnson, M Wright, A Kolesnikov, ...
Bioorganic & Medicinal Chemistry Letters 89, 129277, 2023
12023
The other Erregulla discovery, Wagina Sandstone, north Perth Basin
M Wright, A Cortis, A Sloan, A Farley
The APPEA Journal 63 (1), 247-263, 2023
12023
Cryo-EM reveals an unprecedented binding site for NaV1. 7 inhibitors enabling rational design of potent hybrid inhibitors
M Kschonsak, CC Jao, CP Arthur, AL Rohou, P Bergeron, DF Ortwine, ...
Elife 12, e84151, 2023
82023
New methodology for determining plasma protein binding kinetics using an enzyme reporter assay coupling with High-Resolution mass spectrometry
Z Yan, L Ma, J Huang, P Carione, JR Kenny, CECA Hop, M Wright
Analytical chemistry 95 (8), 4086-4094, 2023
112023
Injectable Polymer‐Nanoparticle Hydrogel for the Sustained Intravitreal Delivery of Bimatoprost
EL Meany, R Andaya, S Tang, CM Kasse, RN Fuji, AK Grosskopf, ...
Advanced Therapeutics 6 (2), 2200207, 2023
62023
Clinical Experience with a Power Injectable Arm Port
M Wright, N Dhaliwal, H Le, B Burbridge
Journal of the Association for Vascular Access 27 (3), 44-48, 2022
2022
Physiologically based pharmacokinetic models can be used to predict the unique nonlinear absorption profiles of vismodegib
L Lin, MR Wright, CECA Hop, H Wong
Drug Metabolism and Disposition 50 (9), 1170-1181, 2022
42022
Reservoir quality and diagenesis of the West Erregulla field, North Perth Basin, Western Australia
M Wright, A Farley, H Karena, A Cortis
The APPEA Journal 62 (2), S508-S513, 2022
12022
Conceptual model of the Lower Permian Kingia Sandstone (northern Perth Basin, Western Australia) as an alternative energy resource
T Meckel, M Wright, G Blair, M Ballesteros, A Farley, A Cortis
The APPEA Journal 62 (2), S449-S455, 2022
2022
Phase I Safety and Feasibility Pilot of Hepatic Artery Infusion Chemotherapy in a Rural Catchment Area Using the Codman-Vascular Catheter with the Synchromed II Pump for …
M Wright, R Jayswal, H Weiss, C Ellis, J Moss, PK Pandalai, J Kim, ...
ANNALS OF SURGICAL ONCOLOGY 29 (SUPPL 2), 534-535, 2022
2022
Opportunities and considerations in the application of artificial intelligence to pharmacokinetic prediction
MR Wright
Artificial Intelligence in Drug Design, 461-482, 2022
52022
Correction to “Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic …
D Zhang, C Wei, CECA Hop, MR Wright, M Hu, Y Lai, SC Khojasteh, ...
Journal of Medicinal Chemistry 64 (21), 16317-16317, 2021
2021
Inhaled JAK inhibitor GDC-4379 reduces FeNO in patients with mild asthma
H Chen, R Kunder, Y Zou, H Gugelmann, J Galanter, R Zhu, R Owen, ...
European Respiratory Journal 58 (suppl 65), 2021
32021
Intestinal excretion, intestinal recirculation, and renal tubule reabsorption are underappreciated mechanisms that drive the distribution and pharmacokinetic behavior of small …
D Zhang, C Wei, CECA Hop, MR Wright, M Hu, Y Lai, SC Khojasteh, ...
Journal of medicinal chemistry 64 (11), 7045-7059, 2021
122021
Nucleophilic Cyclization/Electrophilic Substitution of (2, 2-Dialkoxyethyl) ureas: Highly Regioselective Access to Novel 4-(Het) arylimidazolidinones and Benzo [d][1, 3 …
AV Smolobochkin, AS Gazizov, NK Otegen, JK Voronina, AG Strelnik, ...
Synthesis 52 (21), 3263-3271, 2020
92020
Physiologically based pharmacokinetic model‐informed drug development for polatuzumab vedotin: label for drug‐drug interactions without dedicated clinical trials
D Samineni, H Ding, F Ma, R Shi, D Lu, D Miles, J Mao, C Li, J Jin, ...
The Journal of Clinical Pharmacology 60, S120-S131, 2020
172020
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