Quantitative characterization of the effects of fulvestrant alone or in combination with taselisib (PI3Kinase inhibitor) on longitudinal tumor growth in patients with estrogen … A Moein, JY Jin, MR Wright, H Wong Cancer Chemotherapy and Pharmacology, 1-16, 2024 | | 2024 |
Retrospective Assessment of Translational Pharmacokinetic–Pharmacodynamic Modeling Performance: A Case Study with Apitolisib, a Dual PI3K/mTOR Inhibitor A Moein, JY Jin, MR Wright, B Alicke, H Wong Drugs in R&D, 1-13, 2024 | | 2024 |
GDC-0214 Is a Potent Inhaled JAK Inhibitor With Efficacy in Multiple Pre-clinical Models of Th2 Inflammation: A Perspective on Use of In Vivo Rodent Models for Early Phase Drug … C Rinderknecht Eller, H Rardin, N Sambamurthy, C Thadani, X Wu, J Liu, ... B71. ASTHMA PATHOGENESIS: MORE THAN MEETS THE EYE, A4342-A4342, 2024 | | 2024 |
Quantitative Assessment of Drug Efficacy and Emergence of Resistance in Patients with Metastatic Renal Cell Carcinoma Using a Longitudinal Exposure‐Tumor Growth Inhibition … A Moein, JY Jin, MR Wright, H Wong The Journal of Clinical Pharmacology, 2024 | 2 | 2024 |
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design JJ Crawford, J Feng, HD Brightbill, AR Johnson, M Wright, A Kolesnikov, ... Bioorganic & Medicinal Chemistry Letters 89, 129277, 2023 | 1 | 2023 |
The other Erregulla discovery, Wagina Sandstone, north Perth Basin M Wright, A Cortis, A Sloan, A Farley The APPEA Journal 63 (1), 247-263, 2023 | 1 | 2023 |
Cryo-EM reveals an unprecedented binding site for NaV1. 7 inhibitors enabling rational design of potent hybrid inhibitors M Kschonsak, CC Jao, CP Arthur, AL Rohou, P Bergeron, DF Ortwine, ... Elife 12, e84151, 2023 | 8 | 2023 |
New methodology for determining plasma protein binding kinetics using an enzyme reporter assay coupling with High-Resolution mass spectrometry Z Yan, L Ma, J Huang, P Carione, JR Kenny, CECA Hop, M Wright Analytical chemistry 95 (8), 4086-4094, 2023 | 11 | 2023 |
Injectable Polymer‐Nanoparticle Hydrogel for the Sustained Intravitreal Delivery of Bimatoprost EL Meany, R Andaya, S Tang, CM Kasse, RN Fuji, AK Grosskopf, ... Advanced Therapeutics 6 (2), 2200207, 2023 | 6 | 2023 |
Clinical Experience with a Power Injectable Arm Port M Wright, N Dhaliwal, H Le, B Burbridge Journal of the Association for Vascular Access 27 (3), 44-48, 2022 | | 2022 |
Physiologically based pharmacokinetic models can be used to predict the unique nonlinear absorption profiles of vismodegib L Lin, MR Wright, CECA Hop, H Wong Drug Metabolism and Disposition 50 (9), 1170-1181, 2022 | 4 | 2022 |
Reservoir quality and diagenesis of the West Erregulla field, North Perth Basin, Western Australia M Wright, A Farley, H Karena, A Cortis The APPEA Journal 62 (2), S508-S513, 2022 | 1 | 2022 |
Conceptual model of the Lower Permian Kingia Sandstone (northern Perth Basin, Western Australia) as an alternative energy resource T Meckel, M Wright, G Blair, M Ballesteros, A Farley, A Cortis The APPEA Journal 62 (2), S449-S455, 2022 | | 2022 |
Phase I Safety and Feasibility Pilot of Hepatic Artery Infusion Chemotherapy in a Rural Catchment Area Using the Codman-Vascular Catheter with the Synchromed II Pump for … M Wright, R Jayswal, H Weiss, C Ellis, J Moss, PK Pandalai, J Kim, ... ANNALS OF SURGICAL ONCOLOGY 29 (SUPPL 2), 534-535, 2022 | | 2022 |
Opportunities and considerations in the application of artificial intelligence to pharmacokinetic prediction MR Wright Artificial Intelligence in Drug Design, 461-482, 2022 | 5 | 2022 |
Correction to “Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic … D Zhang, C Wei, CECA Hop, MR Wright, M Hu, Y Lai, SC Khojasteh, ... Journal of Medicinal Chemistry 64 (21), 16317-16317, 2021 | | 2021 |
Inhaled JAK inhibitor GDC-4379 reduces FeNO in patients with mild asthma H Chen, R Kunder, Y Zou, H Gugelmann, J Galanter, R Zhu, R Owen, ... European Respiratory Journal 58 (suppl 65), 2021 | 3 | 2021 |
Intestinal excretion, intestinal recirculation, and renal tubule reabsorption are underappreciated mechanisms that drive the distribution and pharmacokinetic behavior of small … D Zhang, C Wei, CECA Hop, MR Wright, M Hu, Y Lai, SC Khojasteh, ... Journal of medicinal chemistry 64 (11), 7045-7059, 2021 | 12 | 2021 |
Nucleophilic Cyclization/Electrophilic Substitution of (2, 2-Dialkoxyethyl) ureas: Highly Regioselective Access to Novel 4-(Het) arylimidazolidinones and Benzo [d][1, 3 … AV Smolobochkin, AS Gazizov, NK Otegen, JK Voronina, AG Strelnik, ... Synthesis 52 (21), 3263-3271, 2020 | 9 | 2020 |
Physiologically based pharmacokinetic model‐informed drug development for polatuzumab vedotin: label for drug‐drug interactions without dedicated clinical trials D Samineni, H Ding, F Ma, R Shi, D Lu, D Miles, J Mao, C Li, J Jin, ... The Journal of Clinical Pharmacology 60, S120-S131, 2020 | 17 | 2020 |