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Kian-Huat Lim
Kian-Huat Lim
Washington University School of Medicine
在 dom.wustl.edu 的电子邮件经过验证
标题
引用次数
年份
Defining the KRAS-and ERK-dependent transcriptome in KRAS-mutant cancers
JA Klomp, JE Klomp, CA Stalnecker, KL Bryant, AC Edwards, ...
Science 384 (6700), eadk0775, 2024
32024
Avutometinib/defactinib and gemcitabine/nab-paclitaxel combination in first-line metastatic pancreatic ductal adenocarcinoma: Initial safety and efficacy of phase 1b/2 study …
KH Lim, KR Spencer, RA Safyan, VJ Picozzi, AM Varghese, D Siolas, ...
Journal of Clinical Oncology 42 (16_suppl), 4140-4140, 2024
2024
Allele-specific KRAS mutations as prognostic biomarkers in mucinous adenocarcinoma of the appendix and colorectal cancer.
MM Khushman, HM Abushukair, S Alhushki, M Iglesia, KH Lim, X Liu, ...
Journal of Clinical Oncology 42 (16_suppl), 3628-3628, 2024
2024
Molecular insights into oxaliplatin-induced peripheral neuropathy in colorectal cancer: Unraveling a potential signature.
S Modekurty, M Iglesia, KS Pedersen, C Salvador, S Haroutounian, ...
Journal of Clinical Oncology 42 (16_suppl), e15506-e15506, 2024
2024
Abstract CT130: Epacadostat with preoperative chemoradiation in locally advanced rectal cancer (LARC): Results of a translational phase I clinical trial
H Park, K Pedersen, K Huang, M Mutch, H Kim, N Trikalinos, O Aranha, ...
Cancer Research 84 (7_Supplement), CT130-CT130, 2024
2024
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer
A Bulle, P Liu, K Seehra, S Bansod, Y Chen, K Zahra, V Somani, ...
Nature Communications 15 (1), 2503, 2024
22024
Research and Clinical Updates on IRAK4 and Its Roles in Inflammation and Malignancy: Themes and Highlights from the 1st Symposium on IRAK4 in Cancer
G Garcia-Manero, U Platzbecker, KH Lim, G Nowakowski, ...
Frontiers in Hematology 3, 1339870, 2024
22024
Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma
Y Wu, S Chen, X Yang, K Sato, P Lal, Y Wang, AT Shinkle, MC Wendl, ...
Cancer research 83 (24), 4161-4178, 2023
2023
Chemokine Receptor 2 Targeted PET/CT Imaging Distant Metastases in Pancreatic Ductal Adenocarcinoma
X Zhang, L Detering, GS Heo, D Sultan, H Luehmann, L Li, V Somani, ...
ACS Pharmacology & Translational Science 7 (1), 285-293, 2023
2023
A pilot study of paricalcitol plus nanoliposomal irinotecan and 5-FU/LV in advanced pancreatic cancer patients after progression on gemcitabine-based therapy
PM Grierson, R Suresh, B Tan, KS Pedersen, M Amin, H Park, ...
Clinical Cancer Research 29 (23), 4733-4739, 2023
2023
Correction: Defactinib, Pembrolizumab, and Gemcitabine in Patients with Advanced Treatment Refractory Pancreatic Cancer: a Phase I Dose Escalation and Expansion Study
A Wang-Gillam, KH Lim, R McWilliams, R Suresh, AC Lockhart, A Brown, ...
Clinical Cancer Research 29 (22), 4698-4698, 2023
2023
High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival
EP Storrs, P Chati, A Usmani, I Sloan, BA Krasnick, R Babbra, PK Harris, ...
npj Precision Oncology 7 (1), 105, 2023
42023
Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology
UY Panni, MY Chen, F Zhang, DR Cullinan, L Li, CA James, X Zhang, ...
Cancer Immunology, Immunotherapy 72 (8), 2813-2827, 2023
12023
A pilot study of liposomal irinotecan plus 5-FU/LV combined with paricalcitol in patients with advanced pancreatic cancer whose disease progressed on gemcitabine-based therapy.
P Grierson, R Suresh, BR Tan, KS Pedersen, MA Amin, H Park, ...
Journal of Clinical Oncology 41 (16_suppl), e16263-e16263, 2023
2023
STK11 alterations as predictive biomarkers of resistance to immune checkpoint inhibitors in multiple cancers with mismatch repair gene alterations.
M Iglesia, MM Khushman, KH Lim, BA Van Tine, J Liu, KS Pedersen, ...
Journal of Clinical Oncology 41 (16_suppl), 2619-2619, 2023
2023
Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with …
LK Park, KH Lim, J Volkman, M Abdiannia, H Johnston, Z Nigogosyan, ...
Cancer & Metabolism 11 (1), 6, 2023
82023
High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival
A Chaudhuri, E Storrs, P Chati, A Usmani, I Sloan, B Krasnick, RK Babbra, ...
2023
TRIM4 is the E3 ubiquitin-ligase for TPL2/MAP3K8 and is modulated by oncogenic KRAS
SP Bansod, PB Dodhiawala, A Bulle, P Liu, L Li, PM Grierson, J Held, ...
Cancer Research 83 (7_Supplement), 2620-2620, 2023
2023
TNF-MK2 signaling drives protective autophagy following MAPK pathway inhibition in pancreatic cancer
IA Khawar, Q Wei, THP Chen, L Lin, PM Grierson, KH Lim
Cancer Research 83 (7_Supplement), 3870-3870, 2023
2023
Compositions and methods for the treatment of pancreatic cancer
KH Lim, P Grierson
US Patent App. 17/908,863, 2023
2023
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