| Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology T Arulraj, H Wang, A Ippolito, S Zhang, EJ Fertig, AS Popel Briefings in bioinformatics 25 (3), bbae131, 2024 | | 2024 |
| Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth N Furukawa, W Yang, AR Chao, A Patil, AC Mirando, NB Pandey, ... Cell Death Discovery 10 (1), 161, 2024 | | 2024 |
| Integrating spatial multi-omics data with spatial quantitative pharmacology (spQSP) model to simulate human neoadjuvant immunotherapy clinical trial of hepatocellular carcinoma S Zhang, A Deshpande, BK Verma, H Wang, H Mi, L Yuan, WJ Ho, ... Cancer Research 84 (6_Supplement), 2312-2312, 2024 | | 2024 |
| From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling H Wang, T Arulraj, A Ippolito, AS Popel arXiv preprint arXiv:2403.03335, 2024 | | 2024 |
| Signaling-biophysical modeling unravels mechanistic control of red blood cell phagocytosis by macrophages in sickle cell disease Y Zhang, Y Qiang, H Li, G Li, L Lu, M Dao, GE Karniadakis, AS Popel, ... PNAS nexus 3 (2), pgae031, 2024 | 1 | 2024 |
| Bi-level Graph Learning Unveils Prognosis-Relevant Tumor Microenvironment Patterns from Breast Multiplexed Digital Pathology Z Wang, CA Santa-Maria, AS Popel, J Sulam bioRxiv, 2024.04. 22.590118, 2024 | | 2024 |
| Eliciting the antitumor immune response with a conditionally activated PD‐L1 targeting antibody analyzed with a quantitative systems pharmacology model A Ippolito, H Wang, Y Zhang, V Vakil, H Bazzazi, AS Popel CPT: Pharmacometrics & Systems Pharmacology 13 (1), 93-105, 2024 | 2 | 2024 |
| Gel-forming therapeutic peptide exhibits sustained delivery and efficacy in a mouse model of triple-negative breast cancer A Patil, AC Mirando, I Liatsou, G Sgouros, AS Popel, NB Pandey Peptides 169, 171075, 2023 | | 2023 |
| Bi-level Graphs for Cellular Pattern Discovery Z Wang, AS Popel, J Sulam NeurIPS 2023 AI for Science Workshop, 2023 | | 2023 |
| Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells M Song, Y Wang, BH Annex, AS Popel npj Systems Biology and Applications 9 (1), 45, 2023 | 1 | 2023 |
| Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence S Zhang, L Yuan, L Danilova, G Mo, Q Zhu, A Deshpande, ATF Bell, ... Genome medicine 15 (1), 72, 2023 | 20 | 2023 |
| Vascular phenotyping of the invasive front in breast cancer using a 3D angiogenesis atlas A Bhargava, AS Popel, AP Pathak Microvascular Research 149, 104555, 2023 | | 2023 |
| Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial S Zhang, A Deshpande, BK Verma, H Wang, H Mi, L Yuan, WJ Ho, ... bioRxiv, 2023 | 5 | 2023 |
| A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition T Arulraj, H Wang, LA Emens, CA Santa-Maria, AS Popel Science Advances 9 (26), eadg0289, 2023 | 6 | 2023 |
| Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager S Anbari, H Wang, Y Zhang, J Wang, M Pilvankar, M Nickaeen, S Hansel, ... Frontiers in Pharmacology 14, 1163432, 2023 | 4 | 2023 |
| Methods for identifying and preparing pharmaceutical agents for activating Tie1 and/or Tie2 receptors N Pandey, AS Popel, JJ Green, A Mirando US Patent 11,674,959, 2023 | | 2023 |
| Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition H Wang, T Arulraj, H Kimko, AS Popel NPJ Precision Oncology 7 (1), 55, 2023 | 6 | 2023 |
| Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico by a Spatial Quantitative Systems Pharmacology Model M Nikfar, H Mi, C Gong, H Kimko, AS Popel Cancers 15 (10), 2750, 2023 | 4 | 2023 |
| Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway O RHdM, BH Annex, AS Popel | | 2023 |
| Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway RH de Melo Oliveira, BH Annex, AS Popel | | 2023 |
Feilim Mac GabhannAssociate Professor of Biomedical Engineering, Johns Hopkins University在 jhu.edu 的电子邮件经过验证
