Histidine supplementation can escalate or rescue HARS deficiency in a Charcot–Marie–Tooth disease model Y Qiu, R Kenana, A Beharry, SDP Wilhelm, SY Hsu, VM Siu, ... Human Molecular Genetics 32 (5), 810-824, 2023 | 8 | 2023 |
Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease V Ngo, ML Duennwald Antioxidants 11 (12), 2345, 2022 | 138 | 2022 |
Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo RE Lackie, AS de Miranda, MP Lim, V Novikov, N Madrer, ... Acta Neuropathologica 144 (5), 881-910, 2022 | 14 | 2022 |
Folding or holding?—Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease BS Rutledge, WY Choy, ML Duennwald Journal of Biological Chemistry 298 (5), 2022 | 52 | 2022 |
DnaJC7 in amyotrophic lateral sclerosis AA Dilliott, CM Andary, M Stoltz, AA Petropavlovskiy, SMK Farhan, ... International Journal of Molecular Sciences 23 (8), 4076, 2022 | 16 | 2022 |
A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90 V Ngo, A Brickenden, H Liu, C Yeung, WY Choy, ML Duennwald Disease Models & Mechanisms 15 (4), dmm049235, 2022 | 5 | 2022 |
Loss of PrPC modulates expression and localization of stemness markers in glioblastoma stem-like cells MB Prado, RN Alves, RP Iglesia, TG Santos, VR Martins, F Beraldo, J Fan, ... Brain Tumor Research and Treatment 10 (Suppl), 2022 | | 2022 |
Oxidative stress-induced misfolding and inclusion formation of Nrf2 and Keap1 V Ngo, NC Karunatilleke, A Brickenden, WY Choy, ML Duennwald Antioxidants 11 (2), 243, 2022 | 4 | 2022 |
Matrin3: disorder and ALS pathogenesis A Salem, CJ Wilson, BS Rutledge, A Dilliott, S Farhan, WY Choy, ... Frontiers in Molecular Biosciences 8, 794646, 2022 | 15 | 2022 |
Formation and persistence of polyglutamine aggregates in mistranslating cells JT Lant, R Kiri, ML Duennwald, P O’Donoghue Nucleic Acids Research 49 (20), 11883-11899, 2021 | 23 | 2021 |
SPAAC pulse-chase: A novel click chemistry-based method to determine the half-life of cellular proteins TM Morey, MA Esmaeili, ML Duennwald, RJ Rylett Frontiers in Cell and Developmental Biology 9, 722560, 2021 | 6 | 2021 |
A yeast model of the ALS protein Matrin3 uncovers Hsp90 and its co-chaperone Sti1 as modifiers of misfolding and toxicity SE Di Gregorio, M Esmaeili, A Salem, ML Duennwald bioRxiv, 2021.08. 24.457481, 2021 | | 2021 |
Nrf2, the major regulator of the cellular oxidative stress response, is partially disordered NC Karunatilleke, CS Fast, V Ngo, A Brickenden, ML Duennwald, ... International Journal of Molecular Sciences 22 (14), 7434, 2021 | 29 | 2021 |
NAR Breakthrough Article Formation and persistence of polyglutamine JT Lant, R Kiri, ML Duennwald, P O’Donoghue Nucleic Acids Research 49 (20), 11883-11899, 2021 | | 2021 |
A quantitative imaging-based protocol for yeast growth and survival on agar plates AA Petropavlovskiy, MG Tauro, P Lajoie, ML Duennwald STAR protocols 1 (3), 100182, 2020 | 44 | 2020 |
Oxidative stress-induced aggregation of Keap1 impairs Nrf2 regulation V Ngo, N Karunatilleke, Z Song, A Brickenden, M Krstic, WY Choy, ... Free Radical Biology and Medicine 159, S58, 2020 | 3 | 2020 |
Hsp90 and its co-chaperone Sti1 control TDP-43 misfolding and toxicity LTW Lin, A Razzaq, SE Di Gregorio, S Hong, B Charles, MH Lopes, ... bioRxiv, 2020.10. 08.331173, 2020 | 31 | 2020 |
Inclusion formation and toxicity of the ALS protein RGNEF and its association with the microtubule network SE Di Gregorio, K Volkening, MJ Strong, ML Duennwald International journal of molecular sciences 21 (16), 5597, 2020 | 11 | 2020 |
Inclusion Formation and Toxicity of The ALS Protein RGNEF and Its Association with the Microtubule Network M Duennwald, SE Di Gregorio, K Volkening, MJ Strong Preprints, 2020 | | 2020 |
Oxidative stress-induced parkin misfolding, aggregation, and toxicity M Duennwald, GS Shaw, MA Esmaeili, JR Rylett, S Schmid, AS McCarton, ... | | 2020 |