Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, MnTnBuOE-2-PyP5+ (BMX-001) SU Noh, J Lim, SW Shin, Y Kim, WY Park, I Batinic-Haberle, C Choi, ... Antioxidants 13 (4), 477, 2024 | | 2024 |
High-dose ascorbate exerts anti-tumor activities and improves inhibitory effect of carboplatin through the pro-oxidant function pathway in uterine serous carcinoma cell lines X Shen, J Wang, B Deng, S Chen, C John, Z Zhao, N Sinha, J Haag, ... Gynecologic Oncology 183, 93-102, 2024 | 1 | 2024 |
Effect of the nature of the chelated metal on the photodynamic activity of metalloporphyrins G Abbas, F Alibrahim, R Kankouni, S Al-Belushi, DA Al-Mutairi, ... Free Radical Research 57 (6-12), 487-499, 2023 | | 2023 |
Formation and Decomposition of the Mn (II) P-NO Complex In Vitro: Potential Role in Mitochondrial Peroxynitrite Formation V Valez, A Aicardo, S Carballal, V Demicheli, I Batinic-Haberle, D Murgida, ... Free Radical Biology and Medicine 208, S36, 2023 | | 2023 |
LTBK-09. RESULTS OF BMX-HGG STUDY: A MULTI-INSTITUTIONAL, RANDOMIZED PHASE 2 CLINICAL TRIAL OF CONCURRENT CHEMORADIATION WITH OR WITHOUT BMX-001 IN PATIENTS WITH NEWLY … K Peters, A Cohen, N Butowski, J Villano, J Mendez, P Giglio, ... Neuro-oncology 25 (Supplement_5), v311-v311, 2023 | 1 | 2023 |
Intracarotid Infusion of Redox-Active Manganese Porphyrin, MnTnBuOE-2-PyP5+, following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats X Li, W Duan, L Du, D Chu, P Wang, Z Yang, X Qu, Z Yang, ... Antioxidants 12 (10), 1861, 2023 | | 2023 |
Metabolic alterations in A549 human lung cancer cells upon exposure to the redox-active compound MnTnHex-2-PyP5+ alone or combined with cisplatin RB Soares, J Pinto, F Amaro, R Manguinhas, N Gil, I Batinic-Haberle, ... TOXICOLOGY LETTERS 384, S196-S196, 2023 | | 2023 |
Ascorbate exhibits anti-tumorigenic effects in pre-clinical models of endometrioid endometrial cancer (043) C John, X Shen, B Deng, Z Zhao, C Zhou, V Bae-Jump, AA Secord, ... Gynecologic Oncology 176, S37-S38, 2023 | | 2023 |
The Redox-Active Manganese(III) Porphyrin, MnTnBuOE-2-PyP5+, Impairs the Migration and Invasion of Non-Small Cell Lung Cancer Cells, Either Alone or … RB Soares, R Manguinhas, JG Costa, N Saraiva, N Gil, R Rosell, ... Cancers 15 (15), 3814, 2023 | 3 | 2023 |
Mn(III) Porphyrin, MnTnBuOE-2-PyP5+, Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation … S Sharma, P Sharma, U Subedi, S Bhattarai, C Miller, S Manikandan, ... International journal of molecular sciences 24 (7), 6159, 2023 | 3 | 2023 |
MnTnHex-2-PyP5+ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells RB Soares, R Manguinhas, JG Costa, N Saraiva, N Gil, R Rosell, ... Antioxidants 11 (11), 2198, 2022 | 6 | 2022 |
P08-20 Cytotoxic effects of the SOD mimic MnTnHex-2-PyP5+ and its combination with cisplatin in non-small cell lung cancer cells R Soares, R Manguinhas, JG Costa, AS Fernandes, N Saraiva, N Gil, ... Toxicology Letters 368, S148-S149, 2022 | | 2022 |
Redox Regulator MnTnBuOE-PyP5+ Protects Cardiomyocyte Against Oxidative Stress Mediated Myocardial Ischemia/reperfusion Injury S Sharma, S Bhattarai, H Ara, U Subedi, A Shum, F Patel, ... CIRCULATION RESEARCH 131, 2022 | | 2022 |
Abstract P1041: Redox Regulator MnTnBuOE-PyP5+ Protects Cardiomyocyte Against Oxidative Stress Mediated Myocardial Ischemia/reperfusion Injury S Sharma, S Bhattarai, H Ara, U Subedi, A Shum, F Patel, ... Circulation Research 131 (Suppl_1), AP1041-AP1041, 2022 | 1 | 2022 |
SPCR-03 NEUROCOGNITIVE OUTCOMES FROM PHASE 1 TRIAL OF BMX-001 IN COMBINATION WITH CONCURRENT RADIATION THERAPY AND TEMOZOLOMIDE IN NEWLY DIAGNOSED HIGH-GRADE GLIOMA PATIENTS K Peters, J Kirkpatrick, I Batinic-Haberle, ML Affronti, S Woodring, E Lipp, ... Neuro-oncology Advances 4 (Suppl 1), i20, 2022 | | 2022 |
Manganese porphyrin promotes post cardiac arrest recovery in mice and rats P Wang, Y Li, B Yan, Z Yang, L Li, Z Cao, X Li, I Batinic-Haberle, ... Biology 11 (7), 957, 2022 | 8 | 2022 |
Methods, compositions, and kits for treating and/or preventing a side effect associated with radiation and/or chemotherapy exposure K Ashcraft, M Dewhirst, I Batinic-Haberle, JD Crapo US Patent App. 17/691,764, 2022 | | 2022 |
Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same I Batinic-Haberle, A Tovmasyan, I Spasojevic US Patent 11,344,574, 2022 | | 2022 |
Cardioprotective effects of redox regulator MnTnBuOE‐2‐PyP 5+ in myocardial ischemia/reperfusion injury S Sharma, F Patel, S Bhattarai, H Ara, U Subedi, MS Bhuiyan, ... The FASEB Journal 36, 2022 | | 2022 |
Rotenone-induced 4-HNE aggresome formation and degradation in HL-1 cardiomyocytes: role of autophagy flux S Sharma, F Patel, H Ara, E Bess, A Shum, S Bhattarai, U Subedi, DS Bell, ... International Journal of Molecular Sciences 23 (9), 4675, 2022 | 7 | 2022 |