Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer L Zhu, X Zhou, M Gu, J Kim, Y Li, CJ Ko, X Xie, T Gao, X Cheng, SC Sun Nature cell biology 24 (7), 1165-1176, 2022 | 11 | 2022 |
Myeloid cell TBK1 restricts inflammatory responses T Gao, T Liu, CJ Ko, L Zhang, D Joo, X Xie, L Zhu, Y Li, X Cheng, SC Sun Proceedings of the National Academy of Sciences 119 (4), e2107742119, 2022 | 22 | 2022 |
Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death RL Ang, M Chan, D Legarda, JP Sundberg, SC Sun, VL Gillespie, N Chun, ... Proceedings of the National Academy of Sciences 118 (50), e2001602118, 2021 | 10 | 2021 |
DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis Y Li, X Xie, Z Jie, L Zhu, JY Yang, CJ Ko, T Gao, A Jain, SY Jung, N Baran, ... Blood, The Journal of the American Society of Hematology 138 (23), 2360-2371, 2021 | 24 | 2021 |
A Critical Role of Deubiquitinase OTUB1 in Adaptive Cardiac Hypertrophy W Wang, J Li, J Zou, J Ayala, SC Sun, H Su Circulation 144 (Suppl_1), A12936-A12936, 2021 | 3 | 2021 |
Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination L Zhang, CJ Ko, Y Li, Z Jie, L Zhu, X Zhou, X Xie, T Gao, T Liu, X Cheng, ... Cell Reports 37 (4), 2021 | 32 | 2021 |
Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway Z Jie, CJ Ko, H Wang, X Xie, Y Li, M Gu, L Zhu, JY Yang, T Gao, W Ru, ... Science Advances 7 (36), eabh0609, 2021 | 31 | 2021 |
TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells X Xie, L Zhu, Z Jie, Y Li, M Gu, X Zhou, H Wang, JH Chang, CJ Ko, ... Cellular & Molecular Immunology 18 (9), 2262-2274, 2021 | 10 | 2021 |
NF-kappa B-inducing kinase maintains T cell metabolic fitness in antitumor immunity (vol 22, pg 193, 2021) M Gu, X Zhou, JH Sohn, L Zhu, Z Jie, JY Yang, X Zheng, X Xie, J Yang, ... Nature Immunology 22 (4), 530-530, 2021 | | 2021 |
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity M Gu, X Zhou, JH Sohn, L Zhu, Z Jie, JY Yang, X Zheng, X Xie, J Yang, ... Nature immunology 22 (2), 193-204, 2021 | 73 | 2021 |
The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses CJ Ko, L Zhang, Z Jie, L Zhu, X Zhou, X Xie, T Gao, JY Yang, X Cheng, ... The EMBO Journal 40 (2), e104532, 2021 | 15 | 2021 |
Targeting ubiquitin signaling for cancer immunotherapy X Zhou, SC Sun Signal transduction and targeted therapy 6 (1), 16, 2021 | 42 | 2021 |
Intestinal epithelial TBK1 prevents differentiation of T-helper 17 cells and tumorigenesis in mice JY Yang, Z Jie, A Mathews, X Zhou, Y Li, M Gu, X Xie, CJ Ko, X Cheng, ... Gastroenterology 159 (5), 1793-1806, 2020 | 23 | 2020 |
USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2 L Chen, MD Smith, L Lv, T Nakagawa, Z Li, SC Sun, NG Brown, Y Xiong, ... Science Advances 6 (38), eabc9730, 2020 | 31 | 2020 |
Author Correction: The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling J Jin, Y Xiao, JH Chang, J Yu, H Hu, R Starr, GC Brittain, M Chang, ... Nature Immunology 21 (9), 1134-1134, 2020 | 1 | 2020 |
Pellino-1 regulates the responses of the airway to viral infection EK Marsh, EC Prestwich, L Williams, AR Hart, CF Muir, LC Parker, ... Frontiers in Cellular and Infection Microbiology 10, 456, 2020 | 13 | 2020 |
Verteporfin inhibits PD-L1 through autophagy and the STAT1–IRF1–TRIM28 signaling axis, exerting antitumor efficacy J Liang, L Wang, C Wang, J Shen, B Su, AL Marisetty, D Fang, C Kassab, ... Cancer immunology research 8 (7), 952-965, 2020 | 71 | 2020 |
Peli1 signaling blockade attenuates congenital zika syndrome H Luo, G Li, B Wang, B Tian, J Gao, J Zou, S Shi, S Zhu, BH Peng, ... PLoS pathogens 16 (6), e1008538, 2020 | 16 | 2020 |
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination M Deng, JW Tam, L Wang, K Liang, S Li, L Zhang, H Guo, X Luo, Y Zhang, ... Nature communications 11 (1), 2193, 2020 | 37 | 2020 |
A20 restricts inflammation via ubiquitin binding SC Sun Nature Immunology 21 (4), 362-364, 2020 | 8 | 2020 |