Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer H Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, ... Nature Genetics, 1-14, 2024 | | 2024 |
The mutagenic forces shaping the genomic landscape of lung cancer in never smokers M Díaz-Gay, T Zhang, PH Hoang, A Khandekar, W Zhao, CD Steele, ... medRxiv, 2024 | | 2024 |
Abstract LB231: The mutagenic forces shaping the genomic landscape of lung cancer in never smokers M Diaz-Gay, T Zhang, A Khandekar, B Otlu, S Nandi, CD Steele, ... Cancer Research 84 (7_Supplement), LB231-LB231, 2024 | | 2024 |
Multi-modal mutational signatures elucidate the comprehensive consequences of mutational processes CD Steele, L Alexandrov, A Khandekar Cancer Research 84 (6_Supplement), 3563-3563, 2024 | | 2024 |
Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator A Khandekar, R Vangara, M Barnes, M Díaz-Gay, A Abbasi, ... BMC genomics 24 (1), 469, 2023 | 6 | 2023 |
International multicenter study of clinical outcomes of sinonasal melanoma shows survival benefit for patients treated with immune checkpoint inhibitors and potential … M Lechner, Y Takahashi, M Turri-Zanoni, M Ferrari, J Liu, N Counsell, ... Journal of Neurological Surgery Part B: Skull Base 84 (04), 307-319, 2023 | 19 | 2023 |
Mitotic tethering enables inheritance of shattered micronuclear chromosomes P Trivedi, CD Steele, FKC Au, LB Alexandrov, DW Cleveland Nature 618 (7967), 1049-1056, 2023 | 22 | 2023 |
Genomic patterns of malignant peripheral nerve sheath tumor (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA I Cortes-Ciriano, CD Steele, K Piculell, A Al-Ibraheemi, V Eulo, MM Bui, ... Cancer discovery 13 (3), 654-671, 2023 | 26 | 2023 |
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor SMA Islam, M Díaz-Gay, Y Wu, M Barnes, R Vangara, EN Bergstrom, ... Cell genomics 2 (11), 2022 | 171 | 2022 |
Mitotic tethering enables en masse inheritance of a shattered micronuclear chromosome P Trivedi, CD Steele, LB Alexandrov, DW Cleveland bioRxiv, 2022.09. 08.507171, 2022 | 2 | 2022 |
Methods and compositions for high sensitivity sequencing in complex samples JL Snyder, BJ Manning, C Steele, R Smith, HS Giese, YSC Wong, ... US Patent App. 17/274,911, 2022 | | 2022 |
A genetic model for central chondrosarcoma evolution correlates with patient outcome W Cross, I Lyskjær, T Lesluyes, S Hargreaves, AC Strobl, C Davies, ... Genome medicine 14 (1), 99, 2022 | 10 | 2022 |
An overview of mutational and copy number signatures in human cancer CD Steele, N Pillay, LB Alexandrov The Journal of Pathology 257 (4), 454-465, 2022 | 20 | 2022 |
Signatures of copy number alterations in human cancer CD Steele, A Abbasi, SMA Islam, AL Bowes, A Khandekar, K Haase, ... Nature 606 (7916), 984-991, 2022 | 225 | 2022 |
Preprint: Mutation Rate Evolution Drives Immune Escape In Mismatch Repair-Deficient Cancer H Kayhanian, P Barmpoutis, E Lakatos, W Cross, G Caravagna, L Zapata, ... biorxiv. org, 2022 | | 2022 |
Mutation Rate Evolution Drives Immune Escape in Mismatch Repair-Deficient Cancer H Kayhanian, P Barmpoutis, E Lakatos, W Cross, G Caravagna, L Zapata, ... bioRxiv, 2022.03. 06.482973, 2022 | 4 | 2022 |
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA EN Bergstrom, J Luebeck, M Petljak, A Khandekar, M Barnes, T Zhang, ... Nature 602 (7897), 510-517, 2022 | 89 | 2022 |
Multicenter Analysis of Clinical Outcomes of Sinonasal Mucosal Melanoma M Lechner, Y Takahashi, M Turri-Zanoni, M Ferrari, J Liu, N Counsell, ... Journal of Neurological Surgery Part B: Skull Base 83 (S 01), A214, 2022 | | 2022 |
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma M Lechner, Y Takahashi, M Turri-Zanoni, J Liu, N Counsell, M Hermsen, ... European Journal of Cancer 162, 221-236, 2022 | 36 | 2022 |
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma G Zoumpoulidou, C Alvarez-Mendoza, C Mancusi, RM Ahmed, ... Nature communications 12 (1), 7064, 2021 | 23 | 2021 |