关注
Christopher D Steele
Christopher D Steele
未知所在单位机构
在 ucl.ac.uk 的电子邮件经过验证
标题
引用次数
年份
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer
H Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, ...
Nature Genetics, 1-14, 2024
2024
The mutagenic forces shaping the genomic landscape of lung cancer in never smokers
M Díaz-Gay, T Zhang, PH Hoang, A Khandekar, W Zhao, CD Steele, ...
medRxiv, 2024
2024
Abstract LB231: The mutagenic forces shaping the genomic landscape of lung cancer in never smokers
M Diaz-Gay, T Zhang, A Khandekar, B Otlu, S Nandi, CD Steele, ...
Cancer Research 84 (7_Supplement), LB231-LB231, 2024
2024
Multi-modal mutational signatures elucidate the comprehensive consequences of mutational processes
CD Steele, L Alexandrov, A Khandekar
Cancer Research 84 (6_Supplement), 3563-3563, 2024
2024
Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator
A Khandekar, R Vangara, M Barnes, M Díaz-Gay, A Abbasi, ...
BMC genomics 24 (1), 469, 2023
62023
International multicenter study of clinical outcomes of sinonasal melanoma shows survival benefit for patients treated with immune checkpoint inhibitors and potential …
M Lechner, Y Takahashi, M Turri-Zanoni, M Ferrari, J Liu, N Counsell, ...
Journal of Neurological Surgery Part B: Skull Base 84 (04), 307-319, 2023
192023
Mitotic tethering enables inheritance of shattered micronuclear chromosomes
P Trivedi, CD Steele, FKC Au, LB Alexandrov, DW Cleveland
Nature 618 (7967), 1049-1056, 2023
222023
Genomic patterns of malignant peripheral nerve sheath tumor (MPNST) evolution correlate with clinical outcome and are detectable in cell-free DNA
I Cortes-Ciriano, CD Steele, K Piculell, A Al-Ibraheemi, V Eulo, MM Bui, ...
Cancer discovery 13 (3), 654-671, 2023
262023
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor
SMA Islam, M Díaz-Gay, Y Wu, M Barnes, R Vangara, EN Bergstrom, ...
Cell genomics 2 (11), 2022
1712022
Mitotic tethering enables en masse inheritance of a shattered micronuclear chromosome
P Trivedi, CD Steele, LB Alexandrov, DW Cleveland
bioRxiv, 2022.09. 08.507171, 2022
22022
Methods and compositions for high sensitivity sequencing in complex samples
JL Snyder, BJ Manning, C Steele, R Smith, HS Giese, YSC Wong, ...
US Patent App. 17/274,911, 2022
2022
A genetic model for central chondrosarcoma evolution correlates with patient outcome
W Cross, I Lyskjær, T Lesluyes, S Hargreaves, AC Strobl, C Davies, ...
Genome medicine 14 (1), 99, 2022
102022
An overview of mutational and copy number signatures in human cancer
CD Steele, N Pillay, LB Alexandrov
The Journal of Pathology 257 (4), 454-465, 2022
202022
Signatures of copy number alterations in human cancer
CD Steele, A Abbasi, SMA Islam, AL Bowes, A Khandekar, K Haase, ...
Nature 606 (7916), 984-991, 2022
2252022
Preprint: Mutation Rate Evolution Drives Immune Escape In Mismatch Repair-Deficient Cancer
H Kayhanian, P Barmpoutis, E Lakatos, W Cross, G Caravagna, L Zapata, ...
biorxiv. org, 2022
2022
Mutation Rate Evolution Drives Immune Escape in Mismatch Repair-Deficient Cancer
H Kayhanian, P Barmpoutis, E Lakatos, W Cross, G Caravagna, L Zapata, ...
bioRxiv, 2022.03. 06.482973, 2022
42022
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
EN Bergstrom, J Luebeck, M Petljak, A Khandekar, M Barnes, T Zhang, ...
Nature 602 (7897), 510-517, 2022
892022
Multicenter Analysis of Clinical Outcomes of Sinonasal Mucosal Melanoma
M Lechner, Y Takahashi, M Turri-Zanoni, M Ferrari, J Liu, N Counsell, ...
Journal of Neurological Surgery Part B: Skull Base 83 (S 01), A214, 2022
2022
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma
M Lechner, Y Takahashi, M Turri-Zanoni, J Liu, N Counsell, M Hermsen, ...
European Journal of Cancer 162, 221-236, 2022
362022
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma
G Zoumpoulidou, C Alvarez-Mendoza, C Mancusi, RM Ahmed, ...
Nature communications 12 (1), 7064, 2021
232021
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