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François Singh
François Singh
Assistant Professor, University of Iceland
在 hi.is 的电子邮件经过验证
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年份
PINK1 regulated mitophagy is evident in skeletal muscles
F Singh, L Wilhelm, AR Prescott, K Ostacolo, JF Zhao, MH Ogmundsdottir, ...
Autophagy Reports 3 (1), 2024
2024
Proteomic and functional comparison between human induced and embryonic stem cells
AB Murillo, E Griesser, L Sinclair, L Davidson, A Prescott, F Singh, E Hogg, ...
eLife, 1-32, 2024
2024
PINK1 regulated mitophagy is evident in skeletal muscles
F Singh, LP Wilhelm, AR Prescott, K Ostacolo, JF Zhao, ...
bioRxiv, 2023.11. 09.566402, 2023
2023
Physiological functions of mitophagy
M Stanojlovic, A Bishnu, F Singh, IG Ganley
Current Opinion in Physiology 30, 100612, 2022
32022
Discovery of XL01126: a potent, fast, cooperative, selective, orally bioavailable, and blood–brain barrier penetrant PROTAC degrader of leucine-rich repeat kinase 2
X Liu, AF Kalogeropulou, S Domingos, N Makukhin, RS Nirujogi, F Singh, ...
Journal of the American Chemical Society 144 (37), 16930-16952, 2022
762022
Using microscopes to study Parkinson's disease
I Ganley, F Singh, A Cameron, S Soave
2022
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1
O Antico, A Ordureau, M Stevens, F Singh, RS Nirujogi, M Gierlinski, ...
Science Advances 7 (46), eabj0722, 2021
322021
Proteomic and functional comparison between human induced and embryonic stem cells
AJ Brenes, E Griesser, LV Sinclair, L Davidson, AR Prescott, F Singh, ...
bioRxiv, 2021.10. 20.464767, 2021
2021
Impact of Type II LRRK2 inhibitors on signalling and mitophagy
A Tasegian, F Singh, I Ganley, AD Reith, DR Alessi
Biochemical Journal 478 (19), 3555–3573, 2021
432021
Pharmacological rescue of impaired mitophagy in Parkinson’s disease-related LRRK2 G2019S knock-in mice
F Singh, AR Prescott, P Rosewell, G Ball, AD Reith, IG Ganley
elife 10, e67604, 2021
742021
IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes
OJ James, M Vandereyken, JM Marchingo, F Singh, SE Bray, J Wilson, ...
Nature Communications 12 (1), 4290, 2021
162021
Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression
MV Panajatovic, F Singh, S Krähenbühl, J Bouitbir
International Journal of Molecular Sciences 22 (9), 4950, 2021
42021
Parkinson's disease and mitophagy: an emerging role for LRRK2
F Singh, IG Ganley
Biochemical Society Transactions 49 (2), 551-562, 2021
352021
Semi-automated quantitation of macroautophagy with the auto-QC counter
F Singh, G Ball, I Ganley
12020
Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression
MV Panajatovic, F Singh, S Krähenbühl, J Bouitbir
Biomedicines 8 (9), 351, 2020
42020
PGC‐1α plays a pivotal role in simvastatin‐induced exercise impairment in mice
MV Panajatovic, F Singh, NJ Roos, U Duthaler, C Handschin, ...
Acta Physiologica 228 (4), e13402, 2020
132020
Mechanisms of statin-associated skeletal muscle-associated symptoms
J Bouitbir, GM Sanvee, MV Panajatovic, F Singh, S Krähenbühl
Pharmacological research 154, 104201, 2020
1072020
Comprehensive proteomics analyses identify PIM kinases as key regulators of IL-15 driven activation of intestinal intraepithelial lymphocytes
OJ James, M Vanderyken, JM Marchingo, F Singh, AG Love, M Swamy
bioRxiv, 2020.03. 27.011338, 2020
12020
Role of PGC-1-alpha-associated mitochondrial biogenesis in statin-induced myotoxicity
M Panajatovic, F Singh, U Duthaler, S Krähenbühl, J Bouitbir
European Cardiology Review 15, 2020
72020
Semi-automated quantitation of mitophagy in cells and tissues
L Montava-Garriga, F Singh, G Ball, IG Ganley
Mechanisms of ageing and development 185, 111196, 2020
522020
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