PINK1 regulated mitophagy is evident in skeletal muscles F Singh, L Wilhelm, AR Prescott, K Ostacolo, JF Zhao, MH Ogmundsdottir, ... Autophagy Reports 3 (1), 2024 | | 2024 |
Proteomic and functional comparison between human induced and embryonic stem cells AB Murillo, E Griesser, L Sinclair, L Davidson, A Prescott, F Singh, E Hogg, ... eLife, 1-32, 2024 | | 2024 |
PINK1 regulated mitophagy is evident in skeletal muscles F Singh, LP Wilhelm, AR Prescott, K Ostacolo, JF Zhao, ... bioRxiv, 2023.11. 09.566402, 2023 | | 2023 |
Physiological functions of mitophagy M Stanojlovic, A Bishnu, F Singh, IG Ganley Current Opinion in Physiology 30, 100612, 2022 | 3 | 2022 |
Discovery of XL01126: a potent, fast, cooperative, selective, orally bioavailable, and blood–brain barrier penetrant PROTAC degrader of leucine-rich repeat kinase 2 X Liu, AF Kalogeropulou, S Domingos, N Makukhin, RS Nirujogi, F Singh, ... Journal of the American Chemical Society 144 (37), 16930-16952, 2022 | 76 | 2022 |
Using microscopes to study Parkinson's disease I Ganley, F Singh, A Cameron, S Soave | | 2022 |
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1 O Antico, A Ordureau, M Stevens, F Singh, RS Nirujogi, M Gierlinski, ... Science Advances 7 (46), eabj0722, 2021 | 32 | 2021 |
Proteomic and functional comparison between human induced and embryonic stem cells AJ Brenes, E Griesser, LV Sinclair, L Davidson, AR Prescott, F Singh, ... bioRxiv, 2021.10. 20.464767, 2021 | | 2021 |
Impact of Type II LRRK2 inhibitors on signalling and mitophagy A Tasegian, F Singh, I Ganley, AD Reith, DR Alessi Biochemical Journal 478 (19), 3555–3573, 2021 | 43 | 2021 |
Pharmacological rescue of impaired mitophagy in Parkinson’s disease-related LRRK2 G2019S knock-in mice F Singh, AR Prescott, P Rosewell, G Ball, AD Reith, IG Ganley elife 10, e67604, 2021 | 74 | 2021 |
IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes OJ James, M Vandereyken, JM Marchingo, F Singh, SE Bray, J Wilson, ... Nature Communications 12 (1), 4290, 2021 | 16 | 2021 |
Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression MV Panajatovic, F Singh, S Krähenbühl, J Bouitbir International Journal of Molecular Sciences 22 (9), 4950, 2021 | 4 | 2021 |
Parkinson's disease and mitophagy: an emerging role for LRRK2 F Singh, IG Ganley Biochemical Society Transactions 49 (2), 551-562, 2021 | 35 | 2021 |
Semi-automated quantitation of macroautophagy with the auto-QC counter F Singh, G Ball, I Ganley | 1 | 2020 |
Simvastatin Impairs Glucose Homeostasis in Mice Depending on PGC-1α Skeletal Muscle Expression MV Panajatovic, F Singh, S Krähenbühl, J Bouitbir Biomedicines 8 (9), 351, 2020 | 4 | 2020 |
PGC‐1α plays a pivotal role in simvastatin‐induced exercise impairment in mice MV Panajatovic, F Singh, NJ Roos, U Duthaler, C Handschin, ... Acta Physiologica 228 (4), e13402, 2020 | 13 | 2020 |
Mechanisms of statin-associated skeletal muscle-associated symptoms J Bouitbir, GM Sanvee, MV Panajatovic, F Singh, S Krähenbühl Pharmacological research 154, 104201, 2020 | 107 | 2020 |
Comprehensive proteomics analyses identify PIM kinases as key regulators of IL-15 driven activation of intestinal intraepithelial lymphocytes OJ James, M Vanderyken, JM Marchingo, F Singh, AG Love, M Swamy bioRxiv, 2020.03. 27.011338, 2020 | 1 | 2020 |
Role of PGC-1-alpha-associated mitochondrial biogenesis in statin-induced myotoxicity M Panajatovic, F Singh, U Duthaler, S Krähenbühl, J Bouitbir European Cardiology Review 15, 2020 | 7 | 2020 |
Semi-automated quantitation of mitophagy in cells and tissues L Montava-Garriga, F Singh, G Ball, IG Ganley Mechanisms of ageing and development 185, 111196, 2020 | 52 | 2020 |