Interferon type I signaling S Samarajiwa, J Bouwman, K Hanspers, M Van Iersel, E Willighagen, ... | | 2024 |
Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns I Newsham, M Sendera, SG Jammula, SA Samarajiwa Biology Methods and Protocols 9 (1), 2024 | | 2024 |
Abstract PR002: Injury-associated transcriptional state transitions in early renal carcinogenesis S Hirosue, J Ge, L Castillon, P Rodrigues, D Bihary, A Speed, ... Cancer Research 83 (16_Supplement), PR002-PR002, 2023 | | 2023 |
Abstract A015: Injury-associated transcriptional state transitions in early renal carcinogenesis S Hirosue, J Ge, L Castillon, P Rodrigues, D Bihary, A Speed, ... Cancer Research 83 (16_Supplement), A015-A015, 2023 | | 2023 |
Fumarate induces vesicular release of mtDNA to drive innate immunity V Zecchini, V Paupe, I Herranz-Montoya, J Janssen, IMN Wortel, JL Morris, ... Nature 615 (7952), 499-506, 2023 | 106 | 2023 |
Accurate detection of benign and malignant renal tumor subtypes with MethylBoostER: An epigenetic marker–driven learning framework SH Rossi†, I Newsham†, S Pita, K Brennan, G Park, CG Smith, RP Lach, ... Science Advances 8 (39), eabn9828, 2022 | 4 | 2022 |
The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer SA Patel, S Hirosue, P Rodrigues, E Vojtasova, EK Richardson, J Ge, ... Nature 606 (7916), 999-1006, 2022 | 35 | 2022 |
Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate causal variants and target genes of 41 breast cancer risk loci JM Xavier, R Magno, R Russell, BP de Almeida, A Jacinta-Fernandes, ... | 1 | 2022 |
Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate risk variants and target genes of 27 breast cancer risk loci JM Xavier, R Magno, R Russell, BP de Almeida, A Jacinta-Fernandes, ... medRxiv, 2022.03. 08.22271889, 2022 | | 2022 |
PD49-04 ACCURATE DIFFERENTIATION OF PATHOLOGICAL SUBTYPES OF RENAL TUMOUR BY APPLYING A MACHINE LEARNING MODEL TO EPIGENETIC MARKERS S Rossi, I Newsham, S Pita, G Park, R Lach, A Babbage, C Smith, ... Journal of Urology 206 (Supplement 3), e846, 2021 | | 2021 |
Accurate differentiation of renal tumour pathological subtypes using a machine learning model of epigenetic markers S Rossi, I Newsham, S Pita, G Park, R Lach, A Babbage, C Smith, ... European Urology 79, S811, 2021 | | 2021 |
SGK1 mutations in DLBCL generate hyperstable protein neoisoforms that promote AKT independence. J Gao, E Sidiropoulou, I Walker, J Krupka, K Mizielinski, SA Samarajiwa, ... Blood, 2021 | 12 | 2021 |
Neuron type‐specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease R Alcalá‐Vida, M Garcia‐Forn, C Castany‐Pladevall, J Creus‐Muncunill, ... EMBO Molecular Medicine 13 (2), e12105, 2021 | 33 | 2021 |
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence K Tomimatsu, D Bihary, I Olan, A Parry, S Schoenfelder, A Chan, G Slater, ... Nature Aging, 2021 | 18 | 2021 |
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence. K Tomimatsu, D Bihary, I Olan, A Parry, S Schoenfelder, A Chan, ... Research Square, 2020 | | 2020 |
Abstract PO-19: Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis C Gong, JA Krupka, J Gao, NF Grigoropoulos, F Cucco, S Barrans, ... Blood Cancer Discovery 1 (3_Supplement), PO-19-PO-19, 2020 | | 2020 |
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence Ioana Olan, Aled J. Parry, Stefan Schoenfelder, Masako Narita, Yoko Ito ... Nature Communications 11 (6049), 2020 | 53 | 2020 |
Neuron-specific increase in lamin B1 disrupts nuclear function in Huntington’s disease R Alcalá-Vida, M Garcia-Forn, J Creus-Muncunill, Y Ito, E Blanco, ... bioRxiv, 2020.03. 06.979674, 2020 | | 2020 |
Identifying regulatory and spatial genomic architectural elements using cell type independent machine and deep learning models LD Martens, O Faust, L Pirvan, D Bihary, SA Samarajiwa bioRxiv, 2020 | 1 | 2020 |
SpiderSeqR: an R package for crawling the web of high-throughput multi-omic data repositories for useful sequencing data-sets. A Sozanska, C Fletcher, D Bihary, SA Samarajiwa bioRxiv, 2020 | 1* | 2020 |