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Shamith Samarajiwa
Shamith Samarajiwa
Senior Lecturer & Group Leader, Imperial College London
在 imperial.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
年份
Interferon type I signaling
S Samarajiwa, J Bouwman, K Hanspers, M Van Iersel, E Willighagen, ...
2024
Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
I Newsham, M Sendera, SG Jammula, SA Samarajiwa
Biology Methods and Protocols 9 (1), 2024
2024
Abstract PR002: Injury-associated transcriptional state transitions in early renal carcinogenesis
S Hirosue, J Ge, L Castillon, P Rodrigues, D Bihary, A Speed, ...
Cancer Research 83 (16_Supplement), PR002-PR002, 2023
2023
Abstract A015: Injury-associated transcriptional state transitions in early renal carcinogenesis
S Hirosue, J Ge, L Castillon, P Rodrigues, D Bihary, A Speed, ...
Cancer Research 83 (16_Supplement), A015-A015, 2023
2023
Fumarate induces vesicular release of mtDNA to drive innate immunity
V Zecchini, V Paupe, I Herranz-Montoya, J Janssen, IMN Wortel, JL Morris, ...
Nature 615 (7952), 499-506, 2023
1062023
Accurate detection of benign and malignant renal tumor subtypes with MethylBoostER: An epigenetic marker–driven learning framework
SH Rossi†, I Newsham†, S Pita, K Brennan, G Park, CG Smith, RP Lach, ...
Science Advances 8 (39), eabn9828, 2022
42022
The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer
SA Patel, S Hirosue, P Rodrigues, E Vojtasova, EK Richardson, J Ge, ...
Nature 606 (7916), 999-1006, 2022
352022
Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate causal variants and target genes of 41 breast cancer risk loci
JM Xavier, R Magno, R Russell, BP de Almeida, A Jacinta-Fernandes, ...
12022
Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate risk variants and target genes of 27 breast cancer risk loci
JM Xavier, R Magno, R Russell, BP de Almeida, A Jacinta-Fernandes, ...
medRxiv, 2022.03. 08.22271889, 2022
2022
PD49-04 ACCURATE DIFFERENTIATION OF PATHOLOGICAL SUBTYPES OF RENAL TUMOUR BY APPLYING A MACHINE LEARNING MODEL TO EPIGENETIC MARKERS
S Rossi, I Newsham, S Pita, G Park, R Lach, A Babbage, C Smith, ...
Journal of Urology 206 (Supplement 3), e846, 2021
2021
Accurate differentiation of renal tumour pathological subtypes using a machine learning model of epigenetic markers
S Rossi, I Newsham, S Pita, G Park, R Lach, A Babbage, C Smith, ...
European Urology 79, S811, 2021
2021
SGK1 mutations in DLBCL generate hyperstable protein neoisoforms that promote AKT independence.
J Gao, E Sidiropoulou, I Walker, J Krupka, K Mizielinski, SA Samarajiwa, ...
Blood, 2021
122021
Neuron type‐specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease
R Alcalá‐Vida, M Garcia‐Forn, C Castany‐Pladevall, J Creus‐Muncunill, ...
EMBO Molecular Medicine 13 (2), e12105, 2021
332021
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence
K Tomimatsu, D Bihary, I Olan, A Parry, S Schoenfelder, A Chan, G Slater, ...
Nature Aging, 2021
182021
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence.
K Tomimatsu, D  Bihary, I  Olan, A  Parry, S  Schoenfelder, A  Chan, ...
Research Square, 2020
2020
Abstract PO-19: Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
C Gong, JA Krupka, J Gao, NF Grigoropoulos, F Cucco, S Barrans, ...
Blood Cancer Discovery 1 (3_Supplement), PO-19-PO-19, 2020
2020
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence
Ioana Olan, Aled J. Parry, Stefan Schoenfelder, Masako Narita, Yoko Ito ...
Nature Communications 11 (6049), 2020
532020
Neuron-specific increase in lamin B1 disrupts nuclear function in Huntington’s disease
R Alcalá-Vida, M Garcia-Forn, J Creus-Muncunill, Y Ito, E Blanco, ...
bioRxiv, 2020.03. 06.979674, 2020
2020
Identifying regulatory and spatial genomic architectural elements using cell type independent machine and deep learning models
LD Martens, O Faust, L Pirvan, D Bihary, SA Samarajiwa
bioRxiv, 2020
12020
SpiderSeqR: an R package for crawling the web of high-throughput multi-omic data repositories for useful sequencing data-sets.
A Sozanska, C Fletcher, D Bihary, SA Samarajiwa
bioRxiv, 2020
1*2020
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