Atomistic understanding of the RNA-mediated allosteric crosstalk in Cas13a S Sinha, PR Arantes, A Saha, G Palermo Biophysical Journal 121 (3), 286a, 2022 | | 2022 |
BIM binding remotely regulates BAX activation: insights from the free energy landscapes S Sinha, A Maity, S Ghosh Dastidar Journal of Chemical Information and Modeling 58 (2), 370-382, 2018 | 7 | 2018 |
Biophysical origin of adenine base editors’ improved editing efficiency PR Arantes, S Sinha, X Chen, A Saha, AC Patel, M Sample, L Nierzwicki, ... Biophysical Journal 123 (3), 340a, 2024 | | 2024 |
C-terminal tail insertion of Bcl-x L in membrane occurs via partial unfolding and refolding cycle associating microsolvation A Maity, S Sinha, D Ganguly, SG Dastidar Physical Chemistry Chemical Physics 18 (34), 24095-24105, 2016 | 5 | 2016 |
Cholesterol modulates membrane properties and the interaction of gp41 fusion peptide to promote membrane fusion G Meher, S Sinha, GP Pattnaik, S Ghosh Dastidar, H Chakraborty The Journal of Physical Chemistry B 123 (33), 7113-7122, 2019 | 29 | 2019 |
Defining the allosteric role of RNA in the CRISPR-associated Cas13a protein activation S Sinha, AMM Vergas, PR Arantes, AC Patel, M O’Connell, G Palermo Biophysical Journal 122 (3), 48a, 2023 | 1 | 2023 |
Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage HB Belato, C Norbrun, J Luo, C Pindi, S Sinha, AM D’Ordine, G Jogl, ... The Journal of Chemical Physics 157 (22), 2022 | 3 | 2022 |
Dissecting the thermodynamic contributions of the charged residues in the membrane anchoring of Bcl-xl C-terminal domain A Maity, S Sinha, SG Dastidar Chemistry and physics of lipids 218, 112-124, 2019 | 2 | 2019 |
Dynamics and mechanism of a CRISPR-associated transposon AAA+ protein C Pindi, M Ahsan, S Sinha, G Palermo Biophysical Journal 123 (3), 319a, 2024 | | 2024 |
Dynamics and thermostability of HNH nuclease in divergent Cas9 species C Pindi, S Sinha, H Belato, C Norbrun, J Luo, MD Alexandra, G Jogl, ... Biophysical Journal 122 (3), 138a, 2023 | | 2023 |
Establishing the fundamental rules for genetic code expansion S Sinha, M Ahsan, G Palermo Nature chemistry 15 (7), 892-893, 2023 | | 2023 |
High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9 E Skeens, S Sinha, M Ahsan, AM D’Ordine, G Jogl, G Palermo, GP Lisi Science Advances 10 (10), eadl1045, 2024 | 2 | 2024 |
HKT1; 5 transporter gene expression and association of amino acid substitutions with salt tolerance across rice genotypes MUS Shohan, S Sinha, FH Nabila, SG Dastidar, ZI Seraj Frontiers in Plant Science 10, 478257, 2019 | 51 | 2019 |
Machines on genes through the computational microscope S Sinha, C Pindi, M Ahsan, PR Arantes, G Palermo Journal of chemical theory and computation 19 (7), 1945-1964, 2023 | 6 | 2023 |
N-terminal helices and A domain of archaeal FtsY facilitate SRP54 binding and the association with cell membrane S Gupta, S Sinha, K Bhakta, A Bhowmick, A Ghosh bioRxiv, 2022.04. 13.488184, 2022 | | 2022 |
New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity AM Molina Vargas, S Sinha, R Osborn, PR Arantes, A Patel, S Dewhurst, ... Nucleic Acids Research 52 (2), 921-939, 2024 | 5 | 2024 |
New design strategies for ultra-specific CRISPR-Cas13a-based RNA-diagnostic tools with single-nucleotide mismatch sensitivity AM Molina Vargas, RM Osborn, S Sinha, PR Arantes, A Patel, S Dewhurst, ... bioRxiv, 2023.07. 26.550755, 2023 | 3 | 2023 |
RNA-mediated Allosteric Activation in CRISPR-Cas13a S Sinha, AM Molina Vargas, PR Arantes, AC Patel, MR O'Connell, ... bioRxiv, 2023.07. 27.550797, 2023 | | 2023 |
Shifting Polar Residues Across Primary Sequence Frames of Transmembrane Domains Calibrates Membrane Permeation Thermodynamics S Sinha, S Ghosh Dastidar Biochemistry 59 (45), 4353-4366, 2020 | | 2020 |
Twisting and swiveling domain motions in Cas9 to recognize target DNA duplexes, make double-strand breaks, and release cleaved duplexes J Wang, PR Arantes, M Ahsan, S Sinha, GW Kyro, F Maschietto, B Allen, ... Frontiers in molecular biosciences 9, 1072733, 2023 | 4 | 2023 |