1, 3, 4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities MAA Fathi, AA Abd El-Hafeez, D Abdelhamid, SH Abbas, MM Montano, ... Bioorganic chemistry 84, 150-163, 2019 | 59 | 2019 |
2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights MM Elbadawi, WM Eldehna, AA Abd El-Hafeez, WR Somaa, A Albohy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 355-378, 2022 | 21 | 2022 |
A Circuit for Secretion-coupled Cellular Autonomy in Multicellular Eukaryotes L Qiao, S Sinha, AAA El-Hafeez, IC Lo, KK Midde, T Ngo, N Aznar, ... bioRxiv, 2021.03. 18.436048, 2021 | 1 | 2021 |
A circuit for secretion‐coupled cellular autonomy in multicellular eukaryotic cells L Qiao, S Sinha, AA Abd El‐Hafeez, IC Lo, KK Midde, T Ngo, N Aznar, ... Molecular systems biology 19 (4), e11127, 2023 | 9 | 2023 |
A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1, 2, 4-triazoles M Mustafa, AA Abd El-Hafeez, D Abdelhamid, GD Katkar, YA Mostafa, ... European journal of medicinal chemistry 222, 113569, 2021 | 23 | 2021 |
A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding J Ear, AA Abd El-Hafeez, S Roy, T Ngo, N Rajapakse, J Choi, ... Journal of Biological Chemistry 296, 2021 | 10 | 2021 |
A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2/M cell cycle arrest and apoptosis in A549 human lung … AA Abd El-Hafeez, T Fujimura, R Kamei, N Hirakawa, K Baba, K Ono, ... Cytotechnology 70, 899-912, 2018 | 12 | 2018 |
A novel methoxyflavanone from a Chinese medicinal herb (Perilla frutescens) induces G2/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma cells AAAEH Mohamed, T Fujimura, R Kamei, N Hirakawa, K Baba, M Nakano, ... Cancer Research 76 (14_Supplement), 3040-3040, 2016 | | 2016 |
Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway AA Abd El-Hafeez, HMM Marzouk, MAA Abdelhamid, HO Khalifa, ... Biotechnology and Bioprocess Engineering 27 (5), 833-845, 2022 | 6 | 2022 |
Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3 AAA El-Hafeez, HO Khalifa, EAM Mahdy, V Sharma, T Hosoi, P Ghosh, ... Pharmacological Reports 71, 289-298, 2019 | 32 | 2019 |
Clinico-pathological relationship between androgen receptor (AR) and tumor infiltrating lymphocytes (TILs) in triple negative breast cancer (TNBC) H Elghazawy, MO Alorabi, T Helal, A Aref, M Kelany, LAE Abdallah, ... Annals of Oncology 30, iii22-iii23, 2019 | 2 | 2019 |
Clinico-pathological relationship between androgen receptor and tumour infiltrating lymphocytes in triple negative breast cancer H Elghazawy, J Bakkach, T Helal, AM Aref, M Kelany, LE Abdallah, ... ecancermedicalscience 15, 2021 | 5 | 2021 |
Closed Loop Control between Two GTPase Switches makes the Secretory Functions of the Golgi Responsive to Growth Factors L Qiao, IC Lo, KK Midde, N Aznar, AA Abd El-Hafeez, I Lopez-Sanchez, ... | | |
Comparative evaluation of five assays for detection of carbapenemases with a proposed scheme for their precise application HO Khalifa, T Okanda, AA Abd El-Hafeez, A Abd El Latif, AGK Habib, ... The Journal of Molecular Diagnostics 22 (9), 1129-1138, 2020 | 19 | 2020 |
Cytogenetical and ecological studies of some wild congeneric species in the Solanaceae distributed in Upper Egypt MH Abd El-Twab, NAM Barakat, AA Abd El-Hafeez Chromosome Botany 5 (3), 65-73, 2010 | 4 | 2010 |
Design, synthesis and cytotoxicity evaluation of new 3, 5-disubstituted-2-thioxoimidazolidinones KRA Abdellatif, MM Elbadawi, MT Elsaady, AA Abd El-Hafeez, T Fujimura, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 15 | 2018 |
Discovery of antiproliferative and anti-FAK inhibitory activity of 1, 2, 4-triazole derivatives containing acetamido carboxylic acid skeleton M Mustafa, GEDA Abuo-Rahma, AA Abd El-Hafeez, ER Ahmed, ... Bioorganic & medicinal chemistry letters 40, 127965, 2021 | 26 | 2021 |
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer EA Abdelsalam, AA Abd El-Hafeez, WM Eldehna, MA El Hassab, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 2265-2282, 2022 | 17 | 2022 |
DNA glycosylase NEIL2 prevents Fusobacterium-mediated inflammation and DNA damage in colonic epithelial cells IM Sayed, A Chakraborty, A Ali, A Sharma, AZ Sahan, D Sahoo, P Ghosh, ... bioRxiv, 2020.06. 11.147454, 2020 | | 2020 |
Evolution of Modularity, Interactome and Functions of GIV/Girdin (CCDC88A) from Invertebrates to Vertebrates J Ear, A Ali Abd El-Hafeez, S Roy, T Ngo, N Rajapakse, J Choi, ... bioRxiv, 2020.09. 28.317172, 2020 | | 2020 |