454 DIRECT DEMONSTRATION OF AN ANTI-INFLAMMATORY EFFECT OF SIMVASTATIN THERAPY IN THE METABOLIC SYNDROME E Chan, S Devaraj, I Jialal Journal of Investigative Medicine 53 (1), S157-S158, 2005 | | 2005 |
75 In Combat Soldiers Resting Urinary Metabotypes Correlate With the Development of Gastrointestinal Symptoms During Stress LC Phua, CH Wilder-Smith, RK Wong, G Venkatesan, ECY Chan Gastroenterology 148 (4), S-21, 2015 | | 2015 |
A compromised developmental trajectory of the infant gut microbiome and metabolome in atopic eczema LDH Ta, JCY Chan, GC Yap, RW Purbojati, DI Drautz-Moses, YM Koh, ... Gut microbes 12 (1), 1801964, 2020 | 77 | 2020 |
A METABOLISM-DRIVEN COMBINATORIAL APPROACH TO OVERCOME ER/HER2 CROSSTALK IN BREAST CANCER JCY Chan, P Lim, PS Ong, ECY Chan DRUG METABOLISM REVIEWS 47, 110-110, 2015 | | 2015 |
A novel LCMSMS method for quantitative measurement of short-chain fatty acids in human stool derivatized with 12C- and 13C-labelled aniline JCY Chan, DYQ Kioh, GC Yap, BW Lee, ECY Chan Journal of Pharmaceutical and Biomedical Analysis 138, 43-53, 2017 | 84 | 2017 |
An automated LC method for the small-scale purification of organic molecules derived from combinatorial libraries ECY Chan, AW Wang, WP Jia, GD Dollinger Journal of pharmaceutical and biomedical analysis 29 (1-2), 139-146, 2002 | 4 | 2002 |
An automated Pearson's correlation change classification (APC3) approach for GC/MS metabonomic data using total ion chromatograms (TICs) BD Prakash, K Esuvaranathan, PC Ho, KK Pasikanti, ECY Chan, CW Yap Analyst 138 (10), 2883-2889, 2013 | 3 | 2013 |
An exploratory analysis of effects of poyendarone, a deuterated analogue of dronedarone, on the canine model of paroxysmal atrial fibrillation R Kambayashi, A Goto, Y Nunoi, M Hagiwara-Nagasawa, ... Naunyn-Schmiedeberg's Archives of Pharmacology 394 (6), 1103-1112, 2021 | 6 | 2021 |
An investigation of the bioactivation potential and metabolism profile of Zebrafish versus human HT Chng, HK Ho, CW Yap, SH Lam, ECY Chan Journal of biomolecular screening 17 (7), 974-986, 2012 | 66 | 2012 |
Analysis of synthetic derivatives of peptide hormones by capillary zone electrophoresis and micellar electrokinetic chromatography with ultraviolet-absorption and laser-induced … ECY CHAN, PC HO Advances in Chromatography 35 (101), 1995 | 53* | 1995 |
Anti-proliferative effects of raw and steamed extracts of Panax notoginseng and its ginsenoside constituents on human liver cancer cells DF Toh, DN Patel, ECY Chan, A Teo, SY Neo, HL Koh Chinese medicine 6 (1), 1, 2011 | 85 | 2011 |
Antidiabetic effects of multi-species probiotic and its fermented milk in mice via restoring gut microbiota and intestinal barrier Y Gu, X Li, H Chen, Y Sun, L Yang, Y Ma, ECY Chan Food Bioscience 47, 101619, 2022 | 17 | 2022 |
Application of a PBPK Model of Rivaroxaban to Prospective Simulations of Drug-Drug-Disease Interactions with Protein Kinase Inhibitors in CA-VTE EJY Cheong, DZW Ng, SY Chin, Z Wang, ECY Chan Authorea Preprints, 2021 | | 2021 |
Application of a physiologically based pharmacokinetic model of rivaroxaban to prospective simulations of drug–drug–disease interactions with protein kinase inhibitors in … EJY Cheong, DZW Ng, SY Chin, Z Wang, ECY Chan British Journal of Clinical Pharmacology 88 (5), 2267-2283, 2022 | 8 | 2022 |
Application of silica-based monolith as solid phase extraction cartridge for extracting polar compounds from urine T Nema, ECY Chan, PC Ho Talanta 82 (2), 488-494, 2010 | 76 | 2010 |
Application of static modeling in the prediction of in vivo drug–drug interactions between rivaroxaban and antiarrhythmic agents based on in vitro inhibition studies EJY Cheong, JJN Goh, Y Hong, G Venkatesan, Y Liu, GNC Chiu, ... Drug Metabolism and Disposition 45 (3), 260-268, 2017 | 41 | 2017 |
Application of visual basic in high-throughput mass spectrometry-directed purification of combinatorial libraries B Li, ECY Chan Journal of combinatorial chemistry 5 (6), 834-841, 2003 | 9 | 2003 |
Atypical kinetics of cytochrome P450 2J2: Epoxidation of arachidonic acid and reversible inhibition by xenobiotic inhibitors JWH Leow, RK Verma, ABH Lim, H Fan, ECY Chan European Journal of Pharmaceutical Sciences 164, 105889, 2021 | 10 | 2021 |
Atypical kinetics of cytochrome P450 enzymes in pharmacology and toxicology. JWH Leow, LWT Tang, ECY Chan Advances in Pharmacology (San Diego, Calif.) 95, 131-176, 2022 | 7 | 2022 |
Atypical Michaelis-Menten kinetics in cytochrome P450 enzymes: A focus on substrate inhibition JWH Leow, ECY Chan Biochemical Pharmacology 169, 113615, 2019 | 46 | 2019 |