3-substituted 1-Naphthamidomethyl-C-Galactosyls interact with two unique Sub-sites for high-affinity and high-selectivity inhibition of galectin-3 A Dahlqvist, S Mandal, K Peterson, M Håkansson, DT Logan, ... Molecules 24 (24), 4554, 2019 | 7 | 2019 |
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage MJGW Ladds, IMM Van Leeuwen, CJ Drummond, S Chu, AR Healy, ... Nature communications 9 (1), 1107, 2018 | 93 | 2018 |
Amine Transaminase from Exophiala Xenobiotica—Crystal Structure and Engineering of a Fold IV Transaminase that Naturally Converts Biaryl Ketones A Telzerow, J Paris, M Håkansson, J González-Sabín, N Ríos-Lombardía, ... Acs Catalysis 9 (2), 1140-1148, 2018 | 44 | 2018 |
An extended hudrophobic core induces EF‐hand swapping M Håkansson, A Svensson, J Fast, S Linse Protein Science 10 (5), 927-933, 2001 | 49 | 2001 |
ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1 K Enell Smith, S Fritzell, A Nilsson, K Barchan, A Rosén, L Schultz, ... Cancer Immunology, Immunotherapy 72 (12), 4145-4159, 2023 | 3 | 2023 |
Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation M Hassan, S van Klaveren, M Håkansson, C Diehl, R Kovačič, ... European journal of medicinal chemistry 223, 113664, 2021 | 20 | 2021 |
Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH‐Π interactions L Schantz, M Håkansson, DT Logan, E Nordberg‐Karlsson, M Ohlin Proteins: Structure, Function, and Bioinformatics 12 (82), 3466-3475, 2014 | 6 | 2014 |
Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH‐Π interactions L von Schantz, M Håkansson, DT Logan, E Nordberg‐Karlsson, M Ohlin Proteins: Structure, Function, and Bioinformatics 82 (12), 3466-3475, 2014 | 16 | 2014 |
Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction M Håkansson, P Antonsson, P Björk, AL Svensson JBIC Journal of Biological Inorganic Chemistry 6, 757-762, 2001 | 5 | 2001 |
Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6 J Ahlqvist, JA Linares-Pastén, M Håkansson, A Jasilionis, ... Acta Crystallographica Section D: Structural Biology 78 (2), 212-227, 2022 | 4 | 2022 |
Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence K Petersson, M Håkansson, H Nilsson, G Forsberg, LA Svensson, A Liljas, ... The EMBO journal, 2001 | 128 | 2001 |
Crystal structure of DNA polymerase I from Thermus phage G20c J Ahlqvist, JA Linares-Pastén, A Jasilionis, M Welin, M Håkansson, ... Acta Crystallographica Section D: Structural Biology 78 (11), 1384-1398, 2022 | 3 | 2022 |
Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1 G Svensson, W Awad, M Håkansson, K Mani, DT Logan Journal of biological chemistry 287 (17), 14040-14051, 2012 | 69 | 2012 |
Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS S Freitag-Pohl, A Jasilionis, M Håkansson, LA Svensson, R Kovačič, ... Acta Crystallographica Section D: Structural Biology 75 (11), 1028-1039, 2019 | 11 | 2019 |
Crystal structures of the Chromobacterium violaceumω‐transaminase reveal major structural rearrangements upon binding of coenzyme PLP MS Humble, KE Cassimjee, M Håkansson, YR Kimbung, B Walse, ... The FEBS journal 279 (5), 779-792, 2012 | 148 | 2012 |
Current status and future opportunities for serial crystallography at MAX IV Laboratory A Shilova, H Lebrette, O Aurelius, J Nan, M Welin, R Kovacic, S Ghosh, ... Journal of Synchrotron Radiation 27 (5), 1095-1102, 2020 | 13 | 2020 |
Deep interactome learning for de novo drug design K Atz, LC Muñoz, C Isert, M Håkansson, D Focht, DF Nippa, M Hilleke, ... | 2 | 2023 |
Designing interactions by control of protein–ligand complex conformation: tuning arginine–arene interaction geometry for enhanced electrostatic protein–ligand interactions AL Noresson, O Aurelius, CT Öberg, O Engström, AP Sundin, ... Chemical Science 9 (4), 1014-1021, 2018 | 23 | 2018 |
DETAILED STRUCTURAL INFORMATION OF SPECIFICITY DETERMINING INTERACTIONS IN ENGINEERED CARBOHYDRATE BINDING MODULES L von Schantz, M Håkansson, D Logan, B Walse, J Österlin, EN Karlsson, ... 26th International Carbohydrate Symposium, 2012 | | 2012 |
Discovery of selective and orally available galectin-1 inhibitors FR Zetterberg, C Diehl, M Håkansson, B Kahl-Knutson, H Leffler, ... Journal of Medicinal Chemistry 66 (24), 16980-16990, 2023 | 7 | 2023 |