A critical and concise review of mass spectrometry applied to imaging in drug discovery RJA Goodwin, Z Takats, J Bunch SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (9), 963-976, 2020 | 55 | 2020 |
A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability T Vallianatou, N Strittmatter, A Nilsson, M Shariatgorji, G Hamm, ... NeuroImage 172, 808-816, 2018 | 30 | 2018 |
A multi modal mass spectrometry imaging strategy to profile the metabolic hallmarks of colorectal cancer J Bunch, RT Steven, AJ Taylor, SA Thomas, AM Race, A Dexter, G Hamm, ... Cancer Research 78 (13_Supplement), 5661-5661, 2018 | | 2018 |
A SERS-active electrospun polymer mesh for spatially localized pH measurements of the cellular microenvironment WH Skinner, M Chung, S Mitchell, A Akidil, K Fabre, R Goodwin, ... Analytical Chemistry 93 (41), 13844-13851, 2021 | 11 | 2021 |
A solvent‐free matrix application method for matrix‐assisted laser desorption/ionization imaging of small molecules RJ Goodwin, L Macintyre, DG Watson, SP Scullion, AR Pitt Rapid communications in mass spectrometry 24 (11), 1682-1686, 2010 | 44 | 2010 |
Abstract CT214: ATRiUM: A first-in-human dose escalation phase I trial of ceralasertib (AZD6738) and gemcitabine as combination therapy BH de Paula, B Basu, A Mander, J Khan, P Bundi, R Goodwin, ... Cancer Research 81 (13_Supplement), CT214-CT214, 2021 | 1 | 2021 |
Accelerating drug development using spatial multi-omics RJA Goodwin, SJ Platz, JS Reis-Filho, ST Barry Cancer Discovery 14 (4), 620-624, 2024 | 1 | 2024 |
Application of various normalization methods for microscale analysis of tissues using direct analyte probed nanoextraction J De Jesus, J Bunch, G Verbeck, RP Webb, C Costa, RJA Goodwin, ... Analytical chemistry 90 (20), 12094-12100, 2018 | 12 | 2018 |
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging AS Davison, N Strittmatter, H Sutherland, AT Hughes, J Hughes, ... Metabolomics 15, 1-10, 2019 | 32 | 2019 |
Atmospheric-pressure infrared laser-ablation plasma-postionization mass spectrometry imaging of formalin-fixed paraffin-embedded (FFPE) and fresh-frozen tissue sections with no … RT Steven, M Niehaus, AJ Taylor, A Nasif, E Elia, RJA Goodwin, Z Takats, ... Analytical Chemistry 94 (28), 9970-9974, 2022 | 8 | 2022 |
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo S Ashton, YH Song, J Nolan, E Cadogan, J Murray, R Odedra, J Foster, ... Science translational medicine 8 (325), 325ra17-325ra17, 2016 | 222 | 2016 |
Author Correction: Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ... NPJ breast cancer 9, 2023 | | 2023 |
Available online at www. sciencedirect. com RJA Goodwin, A Nilsson, D Borg, PRR Langridge-Smith, DJ Harrison, ... | | |
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer SJ Adua, A Arnal-Estapé, M Zhao, B Qi, ZZ Liu, C Kravitz, H Hulme, ... Nature Communications 13 (1), 7690, 2022 | 10 | 2022 |
Bromopyrylium derivatization facilitates identification by mass spectrometry imaging of monoamine neurotransmitters and small molecule neuroactive compounds R Shariatgorji, A Nilsson, N Strittmatter, T Vallianatou, X Zhang, ... Journal of the american society for mass spectrometry 31 (12), 2553-2557, 2020 | 25 | 2020 |
CBMT-13. UNRAVELLING METABOLISM OF GLIOBLASTOMA USING MASS SPECTROMETRY IMAGING JU Rao, K Gibson, G Hamm, A Wright, M Fala, R Mair, R Goodwin, ... Neuro-oncology, 2018 | | 2018 |
CBMT-33. VISUALIZING THE METABOLISM OF GLIOBLASTOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS BY MASS SPECTROMETRY IMAGING JU Rao, K Gibson, G Hamm, A Wright, M Fala, R Mair, A Tsyben, ... Neuro-Oncology 21 (Suppl 6), vi40, 2019 | | 2019 |
Characterization of an aggregated three-dimensional cell culture model by multimodal mass spectrometry imaging LE Flint, G Hamm, JD Ready, S Ling, CJ Duckett, NA Cross, LM Cole, ... Analytical Chemistry 92 (18), 12538-12547, 2020 | 48 | 2020 |
Characterization of ATM inhibitor (AZD1390) distribution and pharmacodynamic changes in brain and glioblastoma in preclinical models to inform on mechanism of action L Oplustil O'Connor, G Hamm, M Udriste, S Ling, J Wilson, S Durant, ... Cancer Research 80 (16_Supplement), 6168-6168, 2020 | 1 | 2020 |
Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ... NPJ Breast Cancer 9 (1), 64, 2023 | 7 | 2023 |