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Richard J. A. Goodwin
Richard J. A. Goodwin
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
年份
A critical and concise review of mass spectrometry applied to imaging in drug discovery
RJA Goodwin, Z Takats, J Bunch
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (9), 963-976, 2020
552020
A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability
T Vallianatou, N Strittmatter, A Nilsson, M Shariatgorji, G Hamm, ...
NeuroImage 172, 808-816, 2018
302018
A multi modal mass spectrometry imaging strategy to profile the metabolic hallmarks of colorectal cancer
J Bunch, RT Steven, AJ Taylor, SA Thomas, AM Race, A Dexter, G Hamm, ...
Cancer Research 78 (13_Supplement), 5661-5661, 2018
2018
A SERS-active electrospun polymer mesh for spatially localized pH measurements of the cellular microenvironment
WH Skinner, M Chung, S Mitchell, A Akidil, K Fabre, R Goodwin, ...
Analytical Chemistry 93 (41), 13844-13851, 2021
112021
A solvent‐free matrix application method for matrix‐assisted laser desorption/ionization imaging of small molecules
RJ Goodwin, L Macintyre, DG Watson, SP Scullion, AR Pitt
Rapid communications in mass spectrometry 24 (11), 1682-1686, 2010
442010
Abstract CT214: ATRiUM: A first-in-human dose escalation phase I trial of ceralasertib (AZD6738) and gemcitabine as combination therapy
BH de Paula, B Basu, A Mander, J Khan, P Bundi, R Goodwin, ...
Cancer Research 81 (13_Supplement), CT214-CT214, 2021
12021
Accelerating drug development using spatial multi-omics
RJA Goodwin, SJ Platz, JS Reis-Filho, ST Barry
Cancer Discovery 14 (4), 620-624, 2024
12024
Application of various normalization methods for microscale analysis of tissues using direct analyte probed nanoextraction
J De Jesus, J Bunch, G Verbeck, RP Webb, C Costa, RJA Goodwin, ...
Analytical chemistry 90 (20), 12094-12100, 2018
122018
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging
AS Davison, N Strittmatter, H Sutherland, AT Hughes, J Hughes, ...
Metabolomics 15, 1-10, 2019
322019
Atmospheric-pressure infrared laser-ablation plasma-postionization mass spectrometry imaging of formalin-fixed paraffin-embedded (FFPE) and fresh-frozen tissue sections with no …
RT Steven, M Niehaus, AJ Taylor, A Nasif, E Elia, RJA Goodwin, Z Takats, ...
Analytical Chemistry 94 (28), 9970-9974, 2022
82022
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
S Ashton, YH Song, J Nolan, E Cadogan, J Murray, R Odedra, J Foster, ...
Science translational medicine 8 (325), 325ra17-325ra17, 2016
2222016
Author Correction: Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models
L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ...
NPJ breast cancer 9, 2023
2023
Available online at www. sciencedirect. com
RJA Goodwin, A Nilsson, D Borg, PRR Langridge-Smith, DJ Harrison, ...
Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer
SJ Adua, A Arnal-Estapé, M Zhao, B Qi, ZZ Liu, C Kravitz, H Hulme, ...
Nature Communications 13 (1), 7690, 2022
102022
Bromopyrylium derivatization facilitates identification by mass spectrometry imaging of monoamine neurotransmitters and small molecule neuroactive compounds
R Shariatgorji, A Nilsson, N Strittmatter, T Vallianatou, X Zhang, ...
Journal of the american society for mass spectrometry 31 (12), 2553-2557, 2020
252020
CBMT-13. UNRAVELLING METABOLISM OF GLIOBLASTOMA USING MASS SPECTROMETRY IMAGING
JU Rao, K Gibson, G Hamm, A Wright, M Fala, R Mair, R Goodwin, ...
Neuro-oncology, 2018
2018
CBMT-33. VISUALIZING THE METABOLISM OF GLIOBLASTOMA PATIENT-DERIVED ORTHOTOPIC XENOGRAFTS BY MASS SPECTROMETRY IMAGING
JU Rao, K Gibson, G Hamm, A Wright, M Fala, R Mair, A Tsyben, ...
Neuro-Oncology 21 (Suppl 6), vi40, 2019
2019
Characterization of an aggregated three-dimensional cell culture model by multimodal mass spectrometry imaging
LE Flint, G Hamm, JD Ready, S Ling, CJ Duckett, NA Cross, LM Cole, ...
Analytical Chemistry 92 (18), 12538-12547, 2020
482020
Characterization of ATM inhibitor (AZD1390) distribution and pharmacodynamic changes in brain and glioblastoma in preclinical models to inform on mechanism of action
L Oplustil O'Connor, G Hamm, M Udriste, S Ling, J Wilson, S Durant, ...
Cancer Research 80 (16_Supplement), 6168-6168, 2020
12020
Combining the AKT inhibitor capivasertib and SERD fulvestrant is effective in palbociclib-resistant ER+ breast cancer preclinical models
L Hopcroft, EM Wigmore, SC Williamson, S Ros, C Eberlein, JI Moss, ...
NPJ Breast Cancer 9 (1), 64, 2023
72023
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