A computational search for mutational drivers of cancer C Tokheim Johns Hopkins University, 2018 | | 2018 |
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ... Cell systems 7 (4), 422-437. e7, 2018 | 148 | 2018 |
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods N Null, S Jain, C Bakolitsa, SE Brenner, P Radivojac, J Moult, S Repo, ... Genome Biology 25 (1), 1-46, 2024 | 3 | 2024 |
Charting the spatial landscape of cancer hallmarks M Sibai, S Cervilla, D Grases, E Musulen, A Fortian, M Romeo, A Bernat, ... bioRxiv, 2022 | 1 | 2022 |
CHASMplus reveals the scope of somatic missense mutations driving human cancers C Tokheim, R Karchin Cell systems 9 (1), 9-23. e8, 2019 | 105 | 2019 |
Clonal tracing reveals diverse patterns of response to immune checkpoint blockade SS Gu, X Wang, X Hu, P Jiang, Z Li, N Traugh, X Bu, Q Tang, C Wang, ... Genome biology 21, 1-28, 2020 | 17 | 2020 |
Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 2231 | 2018 |
CRAVAT 4: cancer-related analysis of variants toolkit DL Masica, C Douville, C Tokheim, R Bhattacharya, RG Kim, K Moad, ... Cancer research 77 (21), e35-e38, 2017 | 62 | 2017 |
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for computational genetic … S Jain, C Bakolitsa, EB Steven, P Radivojac, J Moult, S Repo, AH Roger, ... Genome Biology 22 (22; 25 (1): 53.), 1-46, 2024 | | 2024 |
Cross-site concordance evaluation of tumor DNA and RNA sequencing platforms for the CIMAC-CIDC Network Z Zeng, J Fu, C Cibulskis, A Jhaveri, C Gumbs, B Das, ... Clinical Cancer Research 27 (18), 5049-5061, 2021 | 6 | 2021 |
Determinants of transcription factor regulatory range CH Chen, R Zheng, C Tokheim, X Dong, J Fan, C Wan, Q Tang, M Brown, ... Nature communications 11 (1), 2472, 2020 | 49 | 2020 |
Discovery of targets for immune–metabolic antitumor drugs identifies estrogen-related receptor alpha A Sahu, X Wang, P Munson, JPG Klomp, X Wang, SS Gu, Y Han, G Qian, ... Cancer discovery 13 (3), 672-701, 2023 | 13 | 2023 |
Evaluating the evaluation of cancer driver genes CJ Tokheim, N Papadopoulos, KW Kinzler, B Vogelstein, R Karchin Proceedings of the National Academy of Sciences 113 (50), 14330-14335, 2016 | 375 | 2016 |
Evaluation of machine learning methods to predict peptide binding to MHC Class I proteins R Bhattacharya, A Sivakumar, C Tokheim, VB Guthrie, V Anagnostou, ... BioRxiv, 154757, 2017 | 40 | 2017 |
Exome-scale discovery of hotspot mutation regions in human cancer using 3D protein structure C Tokheim, R Bhattacharya, N Niknafs, DM Gygax, R Kim, M Ryan, ... Cancer research 76 (13), 3719-3731, 2016 | 142 | 2016 |
Genetic fusions favor tumorigenesis through degron loss in oncogenes J Liu, C Tokheim, JD Lee, W Gan, BJ North, XS Liu, PP Pandolfi, W Wei Nature Communications 12 (1), 6704, 2021 | 18 | 2021 |
Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing CH Chung, VB Guthrie, DL Masica, C Tokheim, H Kang, J Richmon, ... Annals of oncology 26 (6), 1216-1223, 2015 | 194 | 2015 |
High-throughput prediction of MHC class I and II neoantigens with MHCnuggets XM Shao, R Bhattacharya, J Huang, IKA Sivakumar, C Tokheim, L Zheng, ... Cancer immunology research 8 (3), 396-408, 2020 | 125 | 2020 |
Identifying differential alternative splicing events from RNA sequencing data using RNASeq-MATS JW Park, C Tokheim, S Shen, Y Xing Deep sequencing data analysis, 171-179, 2013 | 81 | 2013 |
In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target X Wang, C Tokheim, SS Gu, B Wang, Q Tang, Y Li, N Traugh, Z Zeng, ... Cell 184 (21), 5357-5374. e22, 2021 | 104 | 2021 |