关注
Daniel J. Fazakerley
Daniel J. Fazakerley
MRC Career Development Fellow, Institute of Metabolic Science, Metabolic Research Laboratories
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
年份
A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling
DJ Fazakerley, SP Lawrence, VA Lizunov, SW Cushman, GD Holman
Journal of cell science 122 (5), 727-734, 2009
692009
A gas trapping method for high-throughput metabolic experiments
JR Krycer, C Diskin, ME Nelson, XY Zeng, DJ Fazakerley, DE James
BioTechniques 64 (1), 27-29, 2018
72018
A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology
A Diaz-Vegas, DM Norris, S Jall-Rogg, KC Cooke, OJ Conway, ...
Life science alliance 6 (1), 2023
82023
A NOVEL HUMANSKELETAL MUSCLE IN VITRO MODEL USING OPTI-OX MEDIATED CELLULAR REPROGRAMMING OF INDUCED PLURIPOTENT STEM CELLS
W Bernard, I Geti, E Walters, P Rericha, T Kalkan, M D'Angelo, G Borsari, ...
TISSUE ENGINEERING PART A 28, S318-S318, 2022
2022
A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies
HJM Baird, AS Shun-Shion, EM De Oliveira, D Stalder, L Liang, J Eden, ...
Journal of Biological Chemistry, 107562, 2024
2024
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo
M Kleinert, L Sylow, DJ Fazakerley, JR Krycer, KC Thomas, AJ Oxbøll, ...
Molecular metabolism 3 (6), 630-641, 2014
872014
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ...
Cancer & metabolism 5, 1-14, 2017
3672017
Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
AL Kearney, DM Norris, M Ghomlaghi, M Kin Lok Wong, SJ Humphrey, ...
Elife 10, e66942, 2021
402021
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes
SX Tan, Y Ng, CC Meoli, A Kumar, PS Khoo, DJ Fazakerley, JR Junutula, ...
Journal of Biological Chemistry 287 (9), 6128-6138, 2012
842012
An improved Akt reporter reveals intra-and inter-cellular heterogeneity and oscillations in signal transduction
DM Norris, P Yang, JR Krycer, DJ Fazakerley, DE James, JG Burchfield
Journal of cell science 130 (16), 2757-2766, 2017
262017
Bicarbonate alters cellular responses in respiration assays
JR Krycer, KH Fisher-Wellman, DJ Fazakerley, DM Muoio, DE James
Biochemical and biophysical research communications 489 (4), 399-403, 2017
132017
Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance
W Chen, S Tumanov, DJ Fazakerley, J Cantley, DE James, LL Dunn, ...
Redox Biology 47, 102152, 2021
212021
Circulating AFABP promotes insulin secretion.
LE Wu, DJ Fazakerley, J Cantley
Obesity (19307381) 23 (8), 2015
2015
Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity
R Chaudhuri, PS Khoo, K Tonks, JR Junutula, G Kolumam, Z Modrusan, ...
NPJ systems biology and applications 1 (1), 1-10, 2015
122015
Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway
P Yang, E Patrick, SX Tan, DJ Fazakerley, J Burchfield, C Gribben, ...
Bioinformatics 30 (6), 808-814, 2014
292014
Dynamic 13C flux analysis captures the reorganization of adipocyte glucose metabolism in response to insulin
LE Quek, JR Krycer, S Ohno, K Yugi, DJ Fazakerley, R Scalzo, ...
Iscience 23 (2), 2020
272020
Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2
SJ Humphrey, G Yang, P Yang, DJ Fazakerley, J Stöckli, JY Yang, ...
Cell metabolism 17 (6), 1009-1020, 2013
4462013
Dynamic metabolomics reveals that insulin primes the adipocyte for glucose metabolism
JR Krycer, K Yugi, A Hirayama, DJ Fazakerley, LE Quek, R Scalzo, ...
Cell reports 21 (12), 3536-3547, 2017
622017
Exposure to solar ultraviolet radiation limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice
AL Ferguson, LF Kok, JK Luong, M Van Den Bergh, KS Bell-Anderson, ...
Nutrition, Metabolism and Cardiovascular Diseases 29 (6), 633-638, 2019
272019
Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q
A Ayer, DJ Fazakerley, C Suarna, GJ Maghzal, D Sheipouri, KJ Lee, ...
Redox biology 46, 102127, 2021
142021
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