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Simon J. Charnock
Simon J. Charnock
Prozomix Limited
在 prozomix.com 的电子邮件经过验证 - 首页
标题
引用次数
年份
2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: characterization, modeling and optimization
A Švarc, Z Findrik Blažević, Đ Vasić‐Rački, A Szekrenyi, WD Fessner, ...
Journal of Chemical Technology & Biotechnology 94 (6), 1832-1842, 2019
222019
5-Structure of the Catalytic Domains of Carbohydrate Modifying Enzymes-Structure of a Nucleotide-diphospho-sugar Transferase: Implications for the Synthesis of Polysaccharides
GJ Davies, SJ Charnock
Special Publications of the Royal Society of Chemistry 246, 132-143, 1999
1999
A ‘glyco-fluorine’code revealing differential recognition by glycan binding partners
K Hollingsworth, A Di Maio, SJ Richards, JB Vendeville, DE Wheatley, ...
12023
A biocatalytic approach to a key intermediate for the synthesis of the COVID-19 experimental drug Molnupiravir
A Burke, W Birmingham, Y Zhuo, C BZd, R Crawshaw, T Thorpe, I Rowles, ...
52021
A Coupled Ketoreductase‐Diaphorase Assay for the Detection of Polyethylene Terephthalate‐Hydrolyzing Activity
M Gimeno‐Pérez, JD Finnigan, C Echeverria, SJ Charnock, A Hidalgo, ...
ChemSusChem 15 (9), e202102750, 2022
72022
A method for the systematic selection of enzyme panel candidates by solving the maximum diversity problem
C Atallah, K James, Z Ou, J Skelton, D Markham, MS Burridge, J Finnigan, ...
Biosystems 236, 105105, 2024
22024
A multi-enzyme strategy for the production of a highly valuable lactonized statin side-chain precursor
A Švarc, ZF Blažević, Đ Vasić-Rački, SJ Charnock, AV Presečki
Chemical Engineering Research and Design 164, 35-45, 2020
132020
An asymmetric sp3sp3 cross-electrophile coupling using ‘ene’-reductases
H Fu, J Cao, T Qiao, Y Qi, SJ Charnock, S Garfinkle, TK Hyster
Nature 610 (7931), 302-307, 2022
862022
An Asymmetric sp3–sp3 Cross-Electrophile Coupling Using Biocatalysis
H Fu, J Cao, T Qiao, Y Qi, SJ Charnock, S Garfinkle, TK Hyster
An Efficient Synthesis of the Bicyclic Darunavir Side Chain Using Chemoenzymatic Catalysis
PS Riehl, J Lim, JD Finnigan, SJ Charnock, TK Hyster
Organic Process Research & Development 26 (7), 2096-2101, 2022
92022
An engineered cytidine deaminase for biocatalytic production of a key intermediate of the Covid-19 antiviral molnupiravir
AJ Burke, WR Birmingham, Y Zhuo, TW Thorpe, B Zucoloto da Costa, ...
Journal of the American Chemical Society 144 (9), 3761-3765, 2022
322022
An innovative route for the production of atorvastatin side-chain precursor by DERA-catalysed double aldol addition
A Švarc, M Fekete, K Hernandez, P Clapés, ZF Blažević, A Szekrenyi, ...
Chemical engineering science 231, 116312, 2021
122021
Application of a mathematical model for the optimization of a multi-enzymatic reaction; The case study of L-homoserine synthesis
M Česnik, M Sudar, K Hernandez, P Clapes, S Charnock, Đ Vasić-Rački, ...
5th Multistep Enzyme Catalyzed Processes Congress (MECP 2021), 26-26, 2021
2021
Assay for determination of free D-galactose and/or L-arabinose
BV McCleary, S Charnock
US Patent 7,785,771, 2010
32010
Asymmetric Synthesis of N‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination
P Yao, JR Marshall, Z Xu, J Lim, SJ Charnock, D Zhu, NJ Turner
Angewandte Chemie International Edition 60 (16), 8717-8721, 2021
412021
Automatic Diverse Subset Selection From Enzyme Families by Solving the Maximum Diversity Problem
C Atallah, K James, Z Ou, J Skelton, D Markham, J Finnigan, S Charnock, ...
2022 IEEE Conference on Computational Intelligence in Bioinformatics and …, 2022
2022
Biochemical characterisation of an α1, 4 galactosyltransferase from Neisseria weaveri for the synthesis of α1, 4-linked galactosides
K Huang, A Marchesi, K Hollingsworth, P Both, AP Mattey, E Pallister, ...
Organic & biomolecular chemistry 18 (16), 3142-3148, 2020
102020
Cascade enzymatic synthesis of a statin side chain precursor–the role of reaction engineering in process optimization
M Sudar, N Milčić, MČ Katulić, A Szekrenyi, K Hernández, M Fekete, ...
RSC advances 14 (29), 21158-21173, 2024
2024
Cascade enzymatic synthesis of L-homoserine–mathematical modelling as a tool for process optimisation and design
M Česnik, M Sudar, K Hernández, S Charnock, Đ Vasić-Rački, P Clapés, ...
Reaction chemistry & engineering 5 (4), 747-759, 2020
192020
Cascade Synthesis of l-Homoserine Catalyzed by Lyophilized Whole Cells Containing Transaminase and Aldolase Activities: The Mathematical Modeling Approach
M Česnik Katulić, M Sudar, K Hernández, Y Qi, SJ Charnock, ...
Industrial & engineering chemistry research 60 (38), 13846-13858, 2021
62021
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