关注
CLEMENT OPOKU-TEMENG
CLEMENT OPOKU-TEMENG
Postdoctoral Research Fellow, NIH/NIAID
在 terpmail.umd.edu 的电子邮件经过验证
标题
引用次数
年份
3-Aminooxazolidinone AHL analogs as hydrolytically-stable quorum sensing agonists in Gram-negative bacteria
M Guo, Y Zheng, R Starks, C Opoku-Temeng, X Ma, HO Sintim
MedChemComm 6 (6), 1086-1092, 2015
112015
3H-pyrazolo [4, 3-f] quinoline haspin kinase inhibitors and anticancer properties
C Opoku-Temeng, N Dayal, MA Sooreshjani, HO Sintim
Bioorganic chemistry 78, 418-426, 2018
432018
Agents that inhibit bacterial biofilm formation
N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim
Future medicinal chemistry 7 (5), 647-671, 2015
3152015
Alkynylnicotinamide‐Based Compounds as ABL1 Inhibitors with Potent Activities against Drug‐Resistant CML Harboring ABL1 (T315I) Mutant Kinase
EA Larocque, N Naganna, C Opoku‐Temeng, AM Lambrecht, HO Sintim
ChemMedChem 13 (12), 1172-1180, 2018
172018
Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
N Naganna, C Opoku-Temeng, EY Choi, E Larocque, ET Chang, ...
EBioMedicine 40, 231-239, 2019
152019
Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit proliferation of acute myeloid leukemia cell lines
E Larocque, N Naganna, X Ma, C Opoku-Temeng, B Carter-Cooper, ...
Future medicinal chemistry 9 (11), 1213-1225, 2017
202017
Antibacterial Small Molecules That Potently Inhibit Staphylococcus aureus Lipoteichoic Acid Biosynthesis
GA Naclerio, CW Karanja, C Opoku‐Temeng, HO Sintim
ChemMedChem 14 (10), 1000-1004, 2019
272019
Benzamide antibacterial agents
HO Sintim, M Seleem, C Opoku-Temeng, HT Mohammad, G Naclerio
US Patent App. 18/453,308, 2023
2023
Benzamide antibacterial agents
HO Sintim, M Seleem, C Opoku-Temeng, HT Mohammad, G Naclerio
US Patent 11,731,964, 2023
2023
Biofilm formation mechanisms and targets for developing antibiofilm agents
N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim
Future medicinal chemistry 7 (4), 493-512, 2015
7912015
Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules
C Opoku-Temeng, J Zhou, Y Zheng, J Su, HO Sintim
Chemical Communications 52 (60), 9327-9342, 2016
1012016
Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines
N Dayal, C Opoku-Temeng, DE Hernandez, MA Sooreshjani, ...
Future Medicinal Chemistry 10 (7), 823-835, 2018
252018
Fluorescent 2-aminopurine c-di-GMP and GpG analogs as PDE probes
J Zhou, C Opoku-Temeng, HO Sintim
c-di-GMP Signaling: Methods and Protocols, 245-261, 2017
12017
Fluorescent analogs of cyclic and linear dinucleotides as phosphodiesterase and oligoribonuclease activity probes
J Zhou, Y Zheng, BT Roembke, SM Robinson, C Opoku-Temeng, ...
RSC advances 7 (9), 5421-5426, 2017
112017
Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators
M Guo, Y Zheng, JL Terell, M Ad, C Opoku-Temeng, WE Bentley, ...
Chemical Communications 51 (13), 2617-2620, 2015
152015
Hydroxybenzylidene-indolinones, c-di-AMP synthase inhibitors, have antibacterial and anti-biofilm activities and also re-sensitize resistant bacteria to methicillin and vancomycin
C Opoku-Temeng, N Dayal, J Miller, HO Sintim
RSC advances 7 (14), 8288-8294, 2017
242017
Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols
C Opoku-Temeng, HO Sintim
Scientific Reports 6 (1), 25445, 2016
372016
Inhibition of P. aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative
Y Zheng, G Tsuji, C Opoku-Temeng, HO Sintim
Chemical science 7 (9), 6238-6244, 2016
552016
Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov–Doebner Reactions
N Dayal, C Opoku-Temeng, H Mohammad, NS Abutaleb, D Hernandez, ...
ACS infectious diseases 5 (11), 1820-1830, 2019
162019
Inhibitors of kinase networks and uses thereof
HO Sintim, N Dayal, C Opoku-Temeng
US Patent 11,040,973, 2021
12021
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