3-Aminooxazolidinone AHL analogs as hydrolytically-stable quorum sensing agonists in Gram-negative bacteria M Guo, Y Zheng, R Starks, C Opoku-Temeng, X Ma, HO Sintim MedChemComm 6 (6), 1086-1092, 2015 | 11 | 2015 |
3H-pyrazolo [4, 3-f] quinoline haspin kinase inhibitors and anticancer properties C Opoku-Temeng, N Dayal, MA Sooreshjani, HO Sintim Bioorganic chemistry 78, 418-426, 2018 | 43 | 2018 |
Agents that inhibit bacterial biofilm formation N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (5), 647-671, 2015 | 315 | 2015 |
Alkynylnicotinamide‐Based Compounds as ABL1 Inhibitors with Potent Activities against Drug‐Resistant CML Harboring ABL1 (T315I) Mutant Kinase EA Larocque, N Naganna, C Opoku‐Temeng, AM Lambrecht, HO Sintim ChemMedChem 13 (12), 1172-1180, 2018 | 17 | 2018 |
Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice N Naganna, C Opoku-Temeng, EY Choi, E Larocque, ET Chang, ... EBioMedicine 40, 231-239, 2019 | 15 | 2019 |
Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit proliferation of acute myeloid leukemia cell lines E Larocque, N Naganna, X Ma, C Opoku-Temeng, B Carter-Cooper, ... Future medicinal chemistry 9 (11), 1213-1225, 2017 | 20 | 2017 |
Antibacterial Small Molecules That Potently Inhibit Staphylococcus aureus Lipoteichoic Acid Biosynthesis GA Naclerio, CW Karanja, C Opoku‐Temeng, HO Sintim ChemMedChem 14 (10), 1000-1004, 2019 | 27 | 2019 |
Benzamide antibacterial agents HO Sintim, M Seleem, C Opoku-Temeng, HT Mohammad, G Naclerio US Patent App. 18/453,308, 2023 | | 2023 |
Benzamide antibacterial agents HO Sintim, M Seleem, C Opoku-Temeng, HT Mohammad, G Naclerio US Patent 11,731,964, 2023 | | 2023 |
Biofilm formation mechanisms and targets for developing antibiofilm agents N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (4), 493-512, 2015 | 791 | 2015 |
Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules C Opoku-Temeng, J Zhou, Y Zheng, J Su, HO Sintim Chemical Communications 52 (60), 9327-9342, 2016 | 101 | 2016 |
Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines N Dayal, C Opoku-Temeng, DE Hernandez, MA Sooreshjani, ... Future Medicinal Chemistry 10 (7), 823-835, 2018 | 25 | 2018 |
Fluorescent 2-aminopurine c-di-GMP and GpG analogs as PDE probes J Zhou, C Opoku-Temeng, HO Sintim c-di-GMP Signaling: Methods and Protocols, 245-261, 2017 | 1 | 2017 |
Fluorescent analogs of cyclic and linear dinucleotides as phosphodiesterase and oligoribonuclease activity probes J Zhou, Y Zheng, BT Roembke, SM Robinson, C Opoku-Temeng, ... RSC advances 7 (9), 5421-5426, 2017 | 11 | 2017 |
Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators M Guo, Y Zheng, JL Terell, M Ad, C Opoku-Temeng, WE Bentley, ... Chemical Communications 51 (13), 2617-2620, 2015 | 15 | 2015 |
Hydroxybenzylidene-indolinones, c-di-AMP synthase inhibitors, have antibacterial and anti-biofilm activities and also re-sensitize resistant bacteria to methicillin and vancomycin C Opoku-Temeng, N Dayal, J Miller, HO Sintim RSC advances 7 (14), 8288-8294, 2017 | 24 | 2017 |
Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols C Opoku-Temeng, HO Sintim Scientific Reports 6 (1), 25445, 2016 | 37 | 2016 |
Inhibition of P. aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative Y Zheng, G Tsuji, C Opoku-Temeng, HO Sintim Chemical science 7 (9), 6238-6244, 2016 | 55 | 2016 |
Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov–Doebner Reactions N Dayal, C Opoku-Temeng, H Mohammad, NS Abutaleb, D Hernandez, ... ACS infectious diseases 5 (11), 1820-1830, 2019 | 16 | 2019 |
Inhibitors of kinase networks and uses thereof HO Sintim, N Dayal, C Opoku-Temeng US Patent 11,040,973, 2021 | 1 | 2021 |