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Cyril Corbet
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13C-NMR to study cancer cell metabolic plasticity following PDK inhibition. Influence of dichloroacetate and long-term exposure to acidic environment on glucose and glutamine …
C Schoonjans, N Joudiou, C Corbet, O Feron, B Gallez
296P Identification of metabolism-related therapeutic targets to improve response to neoadjuvant chemotherapy in early breast cancers
F Derouane, CVM de Lummen, J Ambroise, M Berliere, MR Van Bockstal, ...
Annals of Oncology 34, S302, 2023
2023
A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines
A Vessières, C Corbet, JM Heldt, N Lories, N Jouy, I Laïos, G Leclercq, ...
Journal of inorganic biochemistry 104 (5), 503-511, 2010
872010
A new ER-specific photosensitizer unravels 1O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT
A Pinto, Y Mace, F Drouet, E Bony, R Boidot, N Draoui, I Lobysheva, ...
Oncogene 35 (30), 3976-3985, 2016
382016
Acetate: Friend or foe against breast tumour growth in the context of obesity?
C Yelek, L Mignion, N Joudiou, R Terrasi, F Gourgue, M Van Hul, ...
Journal of Cellular and Molecular Medicine 24 (24), 14195-14204, 2020
82020
Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation
C Corbet, A Pinto, R Martherus, JPS de Jesus, F Polet, O Feron
Cell metabolism 24 (2), 311-323, 2016
2932016
Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate
CA Schoonjans, N Joudiou, D Brusa, C Corbet, O Feron, B Gallez
Cancer letters 470, 18-28, 2020
252020
Acidosis-induced TGF-β2 production promotes lipid droplet formation in dendritic cells and alters their potential to support anti-mesothelioma T cell response
N Trempolec, C Degavre, B Doix, D Brusa, C Corbet, O Feron
Cancers 12 (5), 1284, 2020
292020
Acquired resistance to Cetuximab in quadruple wild-type colorectal cancer: role of methylglyoxal stress
F Lardinois, R Crake, J Bellier, M Vara Messler, E Richiardone, O Peulen, ...
EACR-European Association for Cancer Research, 2022
2022
Acquired resistance to EGFR-targeted therapy in quadruple wild-type colorectal cancer: role of methylglyoxal stress
F Lardinois, R Crake, J Bellier, M Vara Messler, E Richiardone, O Peulen, ...
GIGA-Cancer Day, 2021
2021
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation
Q Thémans, C Corbet, O Feron, J Wouters, R Frédérick
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation
Q Spillier, D Vertommen, S Ravez, R Marteau, Q Thémans, C Corbet, ...
Scientific reports 9 (1), 4737, 2019
552019
Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption
S de Mey, H Jiang, C Corbet, H Wang, I Dufait, K Law, E Bastien, ...
Frontiers in Pharmacology 9, 2018
332018
Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
H Wang, S Bouzakoura, S De Mey, H Jiang, K Law, I Dufait, C Corbet, ...
Oncotarget 8 (22), 35728, 2017
742017
Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling
C Corbet, O Feron
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (1), 7-15, 2017
1822017
Combined use of a trka inhibitor and an epha2 inhibitor for using in the treatment of solid cancers, and method for the prognosis of survival of a patient who has a solid cancer
R Toillon, X Le Bourhis, C Corbet, L Aubert, M Guilbert
US Patent App. 15/511,739, 2017
12017
Defining the role of fatty acids in cetuximab resistance in squamous cell carcinoma of the head and neck
C Vandeleene, C Corbet, Y Larondelle
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and …
C Corbet, H Ragelle, V Pourcelle, K Vanvarenberg, J Marchand-Brynaert, ...
Journal of Controlled Release 223, 53-63, 2016
1012016
Design of phosphoglycerate dehydrogenase (PHGDH) inhibitors: A promising target for the development of anticancer agents
Q Spillier, S Ravez, C Corbet, O Feron, R Frédérick
29ème Journées Franco Belges de Pharmacochimie, 2015
2015
Dichloroacetate radiosensitizes hypoxic breast cancer cells
S de Mey, I Dufait, H Jiang, C Corbet, H Wang, M Van De Gucht, ...
International Journal of Molecular Sciences 21 (24), 9367, 2020
212020
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