13C-NMR to study cancer cell metabolic plasticity following PDK inhibition. Influence of dichloroacetate and long-term exposure to acidic environment on glucose and glutamine … C Schoonjans, N Joudiou, C Corbet, O Feron, B Gallez | | |
296P Identification of metabolism-related therapeutic targets to improve response to neoadjuvant chemotherapy in early breast cancers F Derouane, CVM de Lummen, J Ambroise, M Berliere, MR Van Bockstal, ... Annals of Oncology 34, S302, 2023 | | 2023 |
A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines A Vessières, C Corbet, JM Heldt, N Lories, N Jouy, I Laïos, G Leclercq, ... Journal of inorganic biochemistry 104 (5), 503-511, 2010 | 87 | 2010 |
A new ER-specific photosensitizer unravels 1O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT A Pinto, Y Mace, F Drouet, E Bony, R Boidot, N Draoui, I Lobysheva, ... Oncogene 35 (30), 3976-3985, 2016 | 38 | 2016 |
Acetate: Friend or foe against breast tumour growth in the context of obesity? C Yelek, L Mignion, N Joudiou, R Terrasi, F Gourgue, M Van Hul, ... Journal of Cellular and Molecular Medicine 24 (24), 14195-14204, 2020 | 8 | 2020 |
Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation C Corbet, A Pinto, R Martherus, JPS de Jesus, F Polet, O Feron Cell metabolism 24 (2), 311-323, 2016 | 293 | 2016 |
Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate CA Schoonjans, N Joudiou, D Brusa, C Corbet, O Feron, B Gallez Cancer letters 470, 18-28, 2020 | 25 | 2020 |
Acidosis-induced TGF-β2 production promotes lipid droplet formation in dendritic cells and alters their potential to support anti-mesothelioma T cell response N Trempolec, C Degavre, B Doix, D Brusa, C Corbet, O Feron Cancers 12 (5), 1284, 2020 | 29 | 2020 |
Acquired resistance to Cetuximab in quadruple wild-type colorectal cancer: role of methylglyoxal stress F Lardinois, R Crake, J Bellier, M Vara Messler, E Richiardone, O Peulen, ... EACR-European Association for Cancer Research, 2022 | | 2022 |
Acquired resistance to EGFR-targeted therapy in quadruple wild-type colorectal cancer: role of methylglyoxal stress F Lardinois, R Crake, J Bellier, M Vara Messler, E Richiardone, O Peulen, ... GIGA-Cancer Day, 2021 | | 2021 |
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation Q Thémans, C Corbet, O Feron, J Wouters, R Frédérick | | |
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation Q Spillier, D Vertommen, S Ravez, R Marteau, Q Thémans, C Corbet, ... Scientific reports 9 (1), 4737, 2019 | 55 | 2019 |
Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption S de Mey, H Jiang, C Corbet, H Wang, I Dufait, K Law, E Bastien, ... Frontiers in Pharmacology 9, 2018 | 33 | 2018 |
Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species H Wang, S Bouzakoura, S De Mey, H Jiang, K Law, I Dufait, C Corbet, ... Oncotarget 8 (22), 35728, 2017 | 74 | 2017 |
Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling C Corbet, O Feron Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (1), 7-15, 2017 | 182 | 2017 |
Combined use of a trka inhibitor and an epha2 inhibitor for using in the treatment of solid cancers, and method for the prognosis of survival of a patient who has a solid cancer R Toillon, X Le Bourhis, C Corbet, L Aubert, M Guilbert US Patent App. 15/511,739, 2017 | 1 | 2017 |
Defining the role of fatty acids in cetuximab resistance in squamous cell carcinoma of the head and neck C Vandeleene, C Corbet, Y Larondelle | | |
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and … C Corbet, H Ragelle, V Pourcelle, K Vanvarenberg, J Marchand-Brynaert, ... Journal of Controlled Release 223, 53-63, 2016 | 101 | 2016 |
Design of phosphoglycerate dehydrogenase (PHGDH) inhibitors: A promising target for the development of anticancer agents Q Spillier, S Ravez, C Corbet, O Feron, R Frédérick 29ème Journées Franco Belges de Pharmacochimie, 2015 | | 2015 |
Dichloroacetate radiosensitizes hypoxic breast cancer cells S de Mey, I Dufait, H Jiang, C Corbet, H Wang, M Van De Gucht, ... International Journal of Molecular Sciences 21 (24), 9367, 2020 | 21 | 2020 |