159 Stapled-peptides targeting the protein-binding interface of eukaryotic Translation Initiation Factor 4E (eIF4E) protein D Lama, ST Quah, CJ Brown, DP Lane, CS Verma Journal of Biomolecular Structure and Dynamics 33 (sup1), 102-103, 2015 | 4 | 2015 |
41 Applications of the inhibition of Mdm2 function in Cancer Therapy D Lane, C Brown, CF Cheok, C Verma Ejc Supplements 7 (8), 22-23, 2010 | | 2010 |
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays SH Kasper, S Otten, B Squadroni, C Orr‐Terry, Y Kuang, L Mussallem, ... Bioengineering & Translational Medicine, e10542, 2023 | | 2023 |
Assessing the efficacy of Mdm2/Mdm4-inhibiting stapled peptides using cellular thermal shift assays BX Tan, CJ Brown, FJ Ferrer, TY Yuen, ST Quah, BH Chan, AE Jansson, ... Scientific reports 5 (1), 1-9, 2015 | 53 | 2015 |
Assessing the efficacy of Mdm2/Mdm4-inhibiting stapled peptides using cellular thermal shift assays BX Tan, CJ Brown, FJ Ferrer, TY Yuen, ST Quah, BH Chan, AE Jansson, ... Scientific reports 5 (1), 12116, 2015 | 53 | 2015 |
Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides SJ Wei, S Chee, L Yurlova, D Lane, C Verma, C Brown, F Ghadessy Oncotarget 7 (22), 32232, 2016 | 20 | 2016 |
Awakening guardian angels: drugging the p53 pathway CJ Brown, S Lain, CS Verma, AR Fersht, DP Lane Nature Reviews Cancer 9 (12), 862-873, 2009 | 1095 | 2009 |
Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design YS Tan, J Reeks, CJ Brown, D Thean, FJ Ferrer Gago, TY Yuen, ETL Goh, ... The journal of physical chemistry letters 7 (17), 3452-3457, 2016 | 45 | 2016 |
Binding of translationally controlled tumour protein to the N-terminal domain of HDM2 is inhibited by nutlin-3 G Funston, W Goh, SJ Wei, QS Tng, C Brown, LJ Tong, C Verma, D Lane, ... PLoS One 7 (8), e42642, 2012 | 19 | 2012 |
bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA) S Lim, R Khoo, KM Peh, J Teo, SC Chang, S Ng, GL Beilhartz, RA Melnyk, ... Proceedings of the National Academy of Sciences 117 (11), 5791-5800, 2020 | 85 | 2020 |
bioPROTACs as versatile modulators of intracellular therapeutic targets: Application to proliferating cell nuclear antigen (PCNA) S Lim, R Khoo, KM Peh, J Teo, SC Chang, S Ng, GL Beilhartz, RA Melnyk, ... bioRxiv, 728071, 2019 | 1 | 2019 |
C-terminal substitution of MDM2 interacting peptides modulates binding affinity by distinctive mechanisms CJ Brown, SG Dastidar, ST Quah, A Lim, B Chia, CS Verma PLoS One 6 (8), e24122, 2011 | 28 | 2011 |
Conformational ordering of intrinsically disordered peptides for targeting translation initiation CJ Brown, CS Verma, DP Lane, D Lama Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (1), 129775, 2021 | 2 | 2021 |
Correction to: Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides TJ Desai, B Habulihaz, JR Cannon, A Chandramohan, HYK Kaan, ... Pharmaceutical research 38 (4), 735-736, 2021 | | 2021 |
CRYSTAL STRUCTURE OF CAP-FREE HUMAN eIF4E CJ BROWN WO Patent 2,010,138,084, 2010 | | 2010 |
Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site CJ Brown, CS Verma, MD Walkinshaw, DP Lane Cell Cycle 9 (19), 4031-4031, 2010 | 1 | 2010 |
Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site CJ Brown, CS Verma, MD Walkinshaw, DP Lane Cell Cycle 8 (12), 1905-1911, 2009 | 41 | 2009 |
Crystallographic and mass spectrometric characterisation of eIF4E with N 7-alkylated cap derivatives CJ Brown, I McNae, PM Fischer, MD Walkinshaw Journal of molecular biology 372 (1), 7-15, 2007 | 87 | 2007 |
De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits S Ng, YC Juang, A Chandramohan, HYK Kaan, A Sadruddin, TY Yuen, ... ACS Medicinal Chemistry Letters 11 (10), 1993-2001, 2020 | 27 | 2020 |
Design of a novel MDM2 binding peptide based on the p53 family A Madhumalar, LH Jun, CJ Brown, DP Lane, CS Verma Cell Cycle 8 (17), 2828-2836, 2009 | 34 | 2009 |