| An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation (preprint) M Schoof, B Faust, RA Saunders, S Sangwan, VV Rezelj, N Hoppe, ... | | 2020 |
| An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... BioRxiv, 2020 | 62 | 2020 |
| An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 375 | 2020 |
| Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2 CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ... Nature chemical biology 17 (1), 113-121, 2021 | 89 | 2021 |
| Channel-Water Dynamics are Correlated with the Conformational Changes of the M2 Viroporin Protein from Influenza a Virus NH Kim, H Kwon, J Moon, GY Jin, TH Sha, YH No, J Nam, TT Thach, ... Available at SSRN 3699788, 2020 | | 2020 |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 624 | 2020 |
| Consortium QSB, Walter P, Manglik A M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473, 2020 | 10 | 2020 |
| Constructing ion channels from water-soluble α-helical barrels AJ Scott, A Niitsu, HT Kratochvil, EJM Lang, JT Sengel, WM Dawson, ... Nature chemistry 13 (7), 643-650, 2021 | 68 | 2021 |
| Counting tagged molecules one by one: Quantitative photoactivation and bleaching of photoactivatable fluorophores HT Kratochvil, DG Ha, MT Zanni The Journal of Chemical Physics 143 (10), 2015 | 3 | 2015 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes (preprint) K Verba, M Gupta, C Azumaya, M Moritz, S Pourmal, A Diallo, G Merz, ... | | 2021 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... Research square, 2021 | 70 | 2021 |
| CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.(preprint) M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, GM Jang, ... | | 2021 |
| De novo-designed transmembrane proteins bind and regulate a cytokine receptor M Mravic, L He, HT Kratochvil, H Hu, SE Nick, W Bai, A Edwards, H Jo, ... Nature Chemical Biology, 1-10, 2024 | | 2024 |
| Defining the physicochemical basis for proton selectivity through the de novo design of functional proton channels V Silverman, G Prida, A Rohrbach, HT Kratochvil Biophysical Journal 123 (3), 42a, 2024 | | 2024 |
| Designed peptides that assemble into cross-α amyloid-like structures SQ Zhang, H Huang, J Yang, HT Kratochvil, M Lolicato, Y Liu, X Shu, ... Nature Chemical Biology 14 (9), 870-875, 2018 | 65 | 2018 |
| Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology M Mravic, L He, H Kratochvil, H Hu, SE Nick, W Bai, A Edwards, H Jo, ... bioRxiv, 2023.02. 13.526773, 2023 | 1 | 2023 |
| Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 131 | 2021 |
| Glutamine Side Chain 13C═18O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly H Wu, DJ Saltzberg, HT Kratochvil, H Jo, A Sali, WF DeGrado Journal of the American Chemical Society 141 (18), 7320-7326, 2019 | 13 | 2019 |
| Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy HT Kratochvil, JK Carr, K Matulef, AW Annen, H Li, M Maj, J Ostmeyer, ... Science 353 (6303), 1040-1044, 2016 | 205 | 2016 |
| Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor (preprint) P Roboti, KB Duah, G Zong, H Schneider, WQ Shi, S High, ID Young, ... | | 2020 |
