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David Westaway
David Westaway
在 ualberta.ca 的电子邮件经过验证
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引用次数
年份
11C-labeled stilbene derivatives as Aβ-aggregate-specific PET imaging agents for Alzheimer’s disease
M Ono, A Wilson, J Nobrega, D Westaway, P Verhoeff, ZP Zhuang, ...
Nuclear Medicine and Biology 30 (6), 565-571, 2003
2842003
A blue light optogenetic and CRISPR/Cas9 system for inducible PrPC expression
LA Arce, S Wohlgemuth, D Westaway
PRION 13, 13-13, 2019
2019
A cellular gene encodes scrapie PrP 27-30 protein
B Oesch, D Westaway, M Wälchli, MP McKinley, SBH Kent, R Aebersold, ...
Cell 40 (4), 735-746, 1985
20501985
A cluster of familial Creutzfeldt–Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?
P Mastrangelo, L Serpell, T Dafforn, A Lesk, P Fraser, D Westaway
FEBS letters 532 (1-2), 21-26, 2002
92002
A common phenotype polymorphism in mammalian brains defined by concomitant production of prolactin and growth hormone
N Daude, I Lee, TK Kim, C Janus, JP Glaves, H Gapeshina, J Yang, ...
PLoS One 11 (2), e0149410, 2016
82016
A novel ex vivo model for characterization of Alzheimer's disease strains
HE Pineau, G Norman, D Westaway, VL Sim
PRION 13, 30-30, 2019
2019
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS …
RCC Mercer, N Daude, L Dorosh, ZL Fu, CE Mays, H Gapeshina, ...
PLoS pathogens 14 (1), e1006826, 2018
232018
A novel insertion mutation in Prnp causes Gerstmann-Straussler-Scheinker Disease in transgenic mice
R Mercer, C Mays, H Gapeshina, L Dorosh, S Wohlgemuth, N Daude, ...
PRION 9, S65-S65, 2015
2015
A PRION PROTEIN MISSENSE VARIANT IS LINKED TO GERSTMANN-STRAUSSLER SYNDROME
KK HSIAO, HF BAKER, TJ CROW, F OWEN, M POULTER, ...
CLINICAL RESEARCH 37 (2), A541-A541, 1989
1989
Aberrant presenilin-1 expression downregulates LDL receptor-related protein (LRP): is LRP central to Alzheimer's disease pathogenesis?
E Van Uden, G Carlson, PS George-Hyslop, D Westaway, R Orlando, ...
Molecular and Cellular Neuroscience 14 (2), 129-140, 1999
501999
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice
M Ikeda, T Kawarai, T Kawarabayashi, E Matsubara, T Murakami, ...
The American journal of pathology 166 (2), 521-531, 2005
1272005
AChE uses
RG Elles, TR Skern, MEE Hill, JE Arrand, DA Westaway, CGP Mathew, ...
Nature 287 (5782), 480-480, 1980
1980
Actions of β-amyloid protein on human neurons are expressed through the amylin receptor
JH Jhamandas, Z Li, D Westaway, J Yang, S Jassar, D MacTavish
The American journal of pathology 178 (1), 140-149, 2011
992011
Acute dosing of latrepirdine (Dimebon™), a possible Alzheimer therapeutic, elevates extracellular amyloid-β levels in vitro and in vivo
JW Steele, SH Kim, JR Cirrito, DK Verges, JL Restivo, D Westaway, ...
Molecular neurodegeneration 4, 1-11, 2009
512009
Alleles at the Nicastrin locus modify presenilin 1-deficiency phenotype
R Rozmahel, HTJ Mount, F Chen, V Nguyen, J Huang, S Erdebil, J Liauw, ...
Proceedings of the National Academy of Sciences 99 (22), 14452-14457, 2002
272002
Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP+ PS1 transgenic mouse brains
A Amritraj, C Hawkes, AL Phinney, HT Mount, CD Scott, D Westaway, ...
Neurobiology of aging 30 (1), 54-70, 2009
282009
Alzheimer's disease. Antibody clears senile plaques.
SGH PH, DA Westaway
Nature 400 (6740), 116-117, 1999
31999
Amyloid β accelerates phosphorylation of tau and neurofibrillary tangle formation in an amyloid precursor protein and tau double‐transgenic mouse model
Y Seino, T Kawarabayashi, Y Wakasaya, M Watanabe, A Takamura, ...
Journal of neuroscience research 88 (16), 3547-3554, 2010
432010
Amyloid-β seeding effects are dependent on the presence of knock-in genes in the AppNL-G-F mice
SG Lacoursiere, J Safar, D Westaway, MH Mohajerani, RJ Sutherland
bioRxiv, 2022.05. 28.492382, 2022
12022
Amyloid-β-(1-42) increases ryanodine receptor-3 expression and function in neurons of TgCRND8 mice
C Supnet, J Grant, D Westaway, M Mayne
Journal of Biological Chemistry 281 (50), 38440-38447, 2006
1352006
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