Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight DS Umbaugh, H Jaeschke Expert Review of Clinical Pharmacology 17 (2), 143-155, 2024 | 1 | 2024 |
Biomarkers of drug-induced liver injury: A mechanistic perspective through acetaminophen hepatotoxicity DS Umbaugh, H Jaeschke Expert review of gastroenterology & hepatology 15 (4), 363-375, 2021 | 21 | 2021 |
Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice NT Nguyen, DS Umbaugh, S Smith, OB Adelusi, G Sanchez-Guerrero, ... Archives of toxicology 97 (5), 1397-1412, 2023 | 19 | 2023 |
Early Neuronal Inflammation May Be a Contributing Factor to Changes in Epidermal Innervation Associated with Neuropathy in Prediabetic Mice AM Reller, DS Umbaugh, ML Schaller, JC Maciejewski, JS Wooten, ... The FASEB Journal 32, 603.16-603.16, 2018 | | 2018 |
Effects of Fish‐Oils on Markers of Hepatic Steatosis and Cholesterol Homeostasis in C57BL/6 Mice DR Kamm, ML Schaller, D Umbaugh, HM Altenburg, MP Harris, ... The FASEB Journal 32, 760.9-760.9, 2018 | | 2018 |
Effects of Voluntary Wheel Running on Markers of NASH During Weight‐Loss in C57Bl/6 Mice JS Wooten, KE Poole, MP Harris, BL Guilford, ML Schaller, D Umbaugh, ... The FASEB Journal 32, 760.2-760.2, 2018 | | 2018 |
Extracellular vesicles: Roles and applications in drug-induced liver injury DS Umbaugh, H Jaeschke Advances in clinical chemistry 102, 63-125, 2021 | 12 | 2021 |
Hepatocyte senescence is initiated through a Klf6-p21 mechanism which mediates the production of Cxcl14, a novel prognostic biomarker of acute liver failure D Umbaugh, N Nguyen, GS Guerrero, C Villanueva, B Hagenbuch, ... Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | 2 | 2023 |
Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts DS Umbaugh, RP Soder, NT Nguyen, O Adelusi, DR Robarts, ... Archives of toxicology 96 (12), 3315-3329, 2022 | 6 | 2022 |
Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice NT Nguyen, DS Umbaugh, G Sanchez-Guerrero, A Ramachandran, ... Archives of toxicology, 1-16, 2022 | 36 | 2022 |
Mfsd2a and Glut1 brain nutrient transporters expression increase with 32-week low and high lard compared with fish-oil dietary treatment in C57Bl/6 mice KE Sandoval, JS Wooten, MP Harris, ML Schaller, DS Umbaugh, KA Witt Current developments in nutrition 2 (10), nzy065, 2018 | 11 | 2018 |
Mitochondrial dynamics in drug-induced liver injury A Ramachandran, DS Umbaugh, H Jaeschke Livers 1 (3), 102-115, 2021 | 20 | 2021 |
Mitochondrial membrane potential drives early change in mitochondrial morphology after acetaminophen exposure DS Umbaugh, NT Nguyen, H Jaeschke, A Ramachandran Toxicological Sciences 180 (1), 186-195, 2021 | 24 | 2021 |
Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice NT Nguyen, K Du, JY Akakpo, DS Umbaugh, H Jaeschke, ... Toxicology letters 338, 21-31, 2021 | 43 | 2021 |
Neuronal inflammation is associated with changes in epidermal innervation in high fat fed mice DS Umbaugh, JC Maciejewski, JS Wooten, BL Guilford Frontiers in Physiology 13, 891550, 2022 | 2 | 2022 |
Neuronal Inflammation: A Potential Contributing Mechanism to High Fat Diet-Induced Neuropathy DS Umbaugh Southern Illinois University at Edwardsville, 2017 | 1 | 2017 |
Neuronal Inflammation: A Potential Contributing Mechanism to High Fat Diet-Induced Neuropathy: 3586 Board# 33 June 3 8: 00 AM-9: 30 AM DS Umbaugh, JC Maciejewski, BL Guilford Medicine & Science in Sports & Exercise 49 (5S), 1021, 2017 | | 2017 |
Novel Sigma Receptor Ligand Enhances Memory and Mitigates Microglia Proliferation S Bhandari, S Farr, A Silwal, A Crider, A House, D Umbaugh, K Sandoval, ... The FASEB Journal 33 (S1), lb83-lb83, 2019 | | 2019 |
Novel Somatostatin Receptor-4 Agonist SM-I-26 Mitigates Lipopolysaccharide-Induced Inflammatory Gene Expression in Microglia A Silwal, A House, K Sandoval, S Vijeth, D Umbaugh, A Crider, ... Neurochemical research 47 (3), 768-780, 2022 | 3 | 2022 |
Novel therapeutic approaches against acetaminophen-induced liver injury and acute liver failure H Jaeschke, JY Akakpo, DS Umbaugh, A Ramachandran Toxicological Sciences 174 (2), 159-167, 2020 | 133 | 2020 |