关注
David S. Umbaugh
David S. Umbaugh
在 duke.edu 的电子邮件经过验证
标题
引用次数
年份
Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight
DS Umbaugh, H Jaeschke
Expert Review of Clinical Pharmacology 17 (2), 143-155, 2024
12024
Biomarkers of drug-induced liver injury: A mechanistic perspective through acetaminophen hepatotoxicity
DS Umbaugh, H Jaeschke
Expert review of gastroenterology & hepatology 15 (4), 363-375, 2021
212021
Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice
NT Nguyen, DS Umbaugh, S Smith, OB Adelusi, G Sanchez-Guerrero, ...
Archives of toxicology 97 (5), 1397-1412, 2023
192023
Early Neuronal Inflammation May Be a Contributing Factor to Changes in Epidermal Innervation Associated with Neuropathy in Prediabetic Mice
AM Reller, DS Umbaugh, ML Schaller, JC Maciejewski, JS Wooten, ...
The FASEB Journal 32, 603.16-603.16, 2018
2018
Effects of Fish‐Oils on Markers of Hepatic Steatosis and Cholesterol Homeostasis in C57BL/6 Mice
DR Kamm, ML Schaller, D Umbaugh, HM Altenburg, MP Harris, ...
The FASEB Journal 32, 760.9-760.9, 2018
2018
Effects of Voluntary Wheel Running on Markers of NASH During Weight‐Loss in C57Bl/6 Mice
JS Wooten, KE Poole, MP Harris, BL Guilford, ML Schaller, D Umbaugh, ...
The FASEB Journal 32, 760.2-760.2, 2018
2018
Extracellular vesicles: Roles and applications in drug-induced liver injury
DS Umbaugh, H Jaeschke
Advances in clinical chemistry 102, 63-125, 2021
122021
Hepatocyte senescence is initiated through a Klf6-p21 mechanism which mediates the production of Cxcl14, a novel prognostic biomarker of acute liver failure
D Umbaugh, N Nguyen, GS Guerrero, C Villanueva, B Hagenbuch, ...
Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023
22023
Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts
DS Umbaugh, RP Soder, NT Nguyen, O Adelusi, DR Robarts, ...
Archives of toxicology 96 (12), 3315-3329, 2022
62022
Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice
NT Nguyen, DS Umbaugh, G Sanchez-Guerrero, A Ramachandran, ...
Archives of toxicology, 1-16, 2022
362022
Mfsd2a and Glut1 brain nutrient transporters expression increase with 32-week low and high lard compared with fish-oil dietary treatment in C57Bl/6 mice
KE Sandoval, JS Wooten, MP Harris, ML Schaller, DS Umbaugh, KA Witt
Current developments in nutrition 2 (10), nzy065, 2018
112018
Mitochondrial dynamics in drug-induced liver injury
A Ramachandran, DS Umbaugh, H Jaeschke
Livers 1 (3), 102-115, 2021
202021
Mitochondrial membrane potential drives early change in mitochondrial morphology after acetaminophen exposure
DS Umbaugh, NT Nguyen, H Jaeschke, A Ramachandran
Toxicological Sciences 180 (1), 186-195, 2021
242021
Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice
NT Nguyen, K Du, JY Akakpo, DS Umbaugh, H Jaeschke, ...
Toxicology letters 338, 21-31, 2021
432021
Neuronal inflammation is associated with changes in epidermal innervation in high fat fed mice
DS Umbaugh, JC Maciejewski, JS Wooten, BL Guilford
Frontiers in Physiology 13, 891550, 2022
22022
Neuronal Inflammation: A Potential Contributing Mechanism to High Fat Diet-Induced Neuropathy
DS Umbaugh
Southern Illinois University at Edwardsville, 2017
12017
Neuronal Inflammation: A Potential Contributing Mechanism to High Fat Diet-Induced Neuropathy: 3586 Board# 33 June 3 8: 00 AM-9: 30 AM
DS Umbaugh, JC Maciejewski, BL Guilford
Medicine & Science in Sports & Exercise 49 (5S), 1021, 2017
2017
Novel Sigma Receptor Ligand Enhances Memory and Mitigates Microglia Proliferation
S Bhandari, S Farr, A Silwal, A Crider, A House, D Umbaugh, K Sandoval, ...
The FASEB Journal 33 (S1), lb83-lb83, 2019
2019
Novel Somatostatin Receptor-4 Agonist SM-I-26 Mitigates Lipopolysaccharide-Induced Inflammatory Gene Expression in Microglia
A Silwal, A House, K Sandoval, S Vijeth, D Umbaugh, A Crider, ...
Neurochemical research 47 (3), 768-780, 2022
32022
Novel therapeutic approaches against acetaminophen-induced liver injury and acute liver failure
H Jaeschke, JY Akakpo, DS Umbaugh, A Ramachandran
Toxicological Sciences 174 (2), 159-167, 2020
1332020
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