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Thomas Kensler
Thomas Kensler
在 jhu.edu 的电子邮件经过验证 - 首页
标题
引用次数
年份
“MAPping” the course of chemoprevention in breast cancer
NE Davidson, TW Kensler
New England Journal of Medicine 364 (25), 2463-2464, 2011
142011
1-(hydroxyalkyl)-25-hydroxyvitamin D3 analogs of calcitriol. 2. Preliminary biological evaluation
GH Posner, KZ Guyton, TW Kensler, J Barsony, ME Lieberman, GS Reddy, ...
Bioorganic & Medicinal Chemistry Letters 3 (9), 1835-1840, 1993
131993
1. alpha., 25-Dihydroxyvitamin D3 analogs featuring aromatic and heteroaromatic rings: design, synthesis, and preliminary biological testing
GH Posner, Z Li, MC White, V Vinader, K Takeuchi, SE Guggino, P Dolan, ...
Journal of medicinal chemistry 38 (22), 4529-4537, 2002
402002
1α, 25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C, D-ring side-chain
GH Posner, MC White, P Dolan, TW Kensler, S Yukihiro, SE Guggino
Bioorganic & Medicinal Chemistry Letters 4 (24), 2919-2924, 1994
281994
1α, 25-Dihydroxyvitamin D3 Hybrid Analogs with Structural changes at both the A-ring and the C, D-ring side-chain. II
GH Posner, JK Lee, Z Li, K Takeuchi, SE Guggino, P Dolan, TW Kensler
Bioorganic & Medicinal Chemistry Letters 5 (18), 2163-2168, 1995
221995
2, 2-Disubstituted analogues of the natural hormone 1α, 25-dihydroxyvitamin D3: chemistry and biology
GH Posner, BT Woodard, KR Crawford, S Peleg, AJ Brown, P Dolan, ...
Bioorganic & medicinal chemistry 10 (7), 2353-2365, 2002
442002
3H-1, 2-dithiole-3-thione targets nuclear factor κB to block expression of inducible nitric-oxide synthase, prevents hypotension, and improves survival in endotoxemic rats
AR Karuri, Y Huang, S Bodreddigari, CH Sutter, BD Roebuck, TW Kensler, ...
Journal of Pharmacology and Experimental Therapeutics 317 (1), 61-67, 2006
432006
4. Mechanisms of Butylated Hydroxytoluene Hydroperoxide-Stimulated Toxicity and Changes in Gene Expression in Mouse Epidermal Cell Line PA
KZ Guyton, LJ Prestigiacomo, NE Davidson, TW Kensler
Alternative Methods in Toxicology 9, 223, 1993
1993
5,6-Epoxyretinoic acid opposes the effects of 12-O-tetradecanoylphorbol-13-acetate in bovine lymphocytes
PW Wertz, TW Kensler, GC Mueller, AK Verma, RK Boutwell
Nature 277 (5693), 227-229, 1979
501979
A Bayesian approach estimating treatment effects on biomarkers containing zeros with detection limits
H Chu, L Nie, TW Kensler
Statistics in medicine 27 (13), 2497-2508, 2008
112008
A facile enzymatic technique for the estimation of nanomolar concentrations of N-phosphonacetyl-l-aspartic acid in plasma
TW Kensler, HN Jayaram, DA Cooney
Journal of Biochemical and Biophysical Methods 2 (1-2), 29-35, 1980
61980
A facile tritium release assay for mammalian L-dihydroorotate dehydrogenase
TW Kensler, DA Cooney, HN Jayaram, C Schaeffer, DD Choie
Analytical biochemistry 117 (2), 315-319, 1981
81981
A genetic strategy to identify, validate and use gene signatures of xenobiotic-responsive transcription factors in prediction of pathway activation in the mouse liver
K Oshida, N Vasani, M Rosen, B Abbott, C Lau, B Chorley, S Hester, ...
DRUG METABOLISM REVIEWS 43, 183-184, 2011
2011
A Highlights from MBoC Selection: Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
D Volonte, Z Liu, PM Musille, E Stoppani, N Wakabayashi, YP Di, ...
Molecular Biology of the Cell 24 (12), 1852, 2013
2013
A non-calcemic sulfone version of the vitamin D3 analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin
GH Posner, KR Crawford, S Peleg, JE Welsh, S Romu, DA Gewirtz, ...
Bioorganic & medicinal chemistry 9 (9), 2365-2371, 2001
342001
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin
K Liby, MM Yore, BD Roebuck, KJ Baumgartner, T Honda, ...
Cancer research 68 (16), 6727-6733, 2008
592008
A novel synthetic tricyclic compound with an acetylene group at C-8a and cyano enones in rings A and C is a potent multifunctional agent in vitro and suppresses the formation …
K Liby, T Honda, M Yore, C Sundararajan, H Yoshizawa, R Risingsong, ...
Molecular Cancer Therapeutics 6 (11_Supplement), B66-B66, 2007
2007
A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells
L Baird, K Taguchi, A Zhang, Y Takahashi, T Suzuki, TW Kensler, ...
Redox Biology 66, 102845, 2023
72023
A point mutation at C151 of Keap1 of mice abrogates NRF2 signaling, cytoprotection in vitro, and hepatoprotection in vivo by bardoxolone methyl (CDDO-Me)
T Gatbonton-Schwager, Y Yagishita, T Joshi, N Wakabayashi, ...
Molecular pharmacology 104 (2), 51-61, 2023
52023
A ROLE FOR FREE-RADICALS IN THE PROCESS OF TUMOR PROMOTION
BG TAFFE, TW KENSLER
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY 65 (4), 494-494, 1988
1988
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