“MAPping” the course of chemoprevention in breast cancer NE Davidson, TW Kensler New England Journal of Medicine 364 (25), 2463-2464, 2011 | 14 | 2011 |
1-(hydroxyalkyl)-25-hydroxyvitamin D3 analogs of calcitriol. 2. Preliminary biological evaluation GH Posner, KZ Guyton, TW Kensler, J Barsony, ME Lieberman, GS Reddy, ... Bioorganic & Medicinal Chemistry Letters 3 (9), 1835-1840, 1993 | 13 | 1993 |
1. alpha., 25-Dihydroxyvitamin D3 analogs featuring aromatic and heteroaromatic rings: design, synthesis, and preliminary biological testing GH Posner, Z Li, MC White, V Vinader, K Takeuchi, SE Guggino, P Dolan, ... Journal of medicinal chemistry 38 (22), 4529-4537, 2002 | 40 | 2002 |
1α, 25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C, D-ring side-chain GH Posner, MC White, P Dolan, TW Kensler, S Yukihiro, SE Guggino Bioorganic & Medicinal Chemistry Letters 4 (24), 2919-2924, 1994 | 28 | 1994 |
1α, 25-Dihydroxyvitamin D3 Hybrid Analogs with Structural changes at both the A-ring and the C, D-ring side-chain. II GH Posner, JK Lee, Z Li, K Takeuchi, SE Guggino, P Dolan, TW Kensler Bioorganic & Medicinal Chemistry Letters 5 (18), 2163-2168, 1995 | 22 | 1995 |
2, 2-Disubstituted analogues of the natural hormone 1α, 25-dihydroxyvitamin D3: chemistry and biology GH Posner, BT Woodard, KR Crawford, S Peleg, AJ Brown, P Dolan, ... Bioorganic & medicinal chemistry 10 (7), 2353-2365, 2002 | 44 | 2002 |
3H-1, 2-dithiole-3-thione targets nuclear factor κB to block expression of inducible nitric-oxide synthase, prevents hypotension, and improves survival in endotoxemic rats AR Karuri, Y Huang, S Bodreddigari, CH Sutter, BD Roebuck, TW Kensler, ... Journal of Pharmacology and Experimental Therapeutics 317 (1), 61-67, 2006 | 43 | 2006 |
4. Mechanisms of Butylated Hydroxytoluene Hydroperoxide-Stimulated Toxicity and Changes in Gene Expression in Mouse Epidermal Cell Line PA KZ Guyton, LJ Prestigiacomo, NE Davidson, TW Kensler Alternative Methods in Toxicology 9, 223, 1993 | | 1993 |
5,6-Epoxyretinoic acid opposes the effects of 12-O-tetradecanoylphorbol-13-acetate in bovine lymphocytes PW Wertz, TW Kensler, GC Mueller, AK Verma, RK Boutwell Nature 277 (5693), 227-229, 1979 | 50 | 1979 |
A Bayesian approach estimating treatment effects on biomarkers containing zeros with detection limits H Chu, L Nie, TW Kensler Statistics in medicine 27 (13), 2497-2508, 2008 | 11 | 2008 |
A facile enzymatic technique for the estimation of nanomolar concentrations of N-phosphonacetyl-l-aspartic acid in plasma TW Kensler, HN Jayaram, DA Cooney Journal of Biochemical and Biophysical Methods 2 (1-2), 29-35, 1980 | 6 | 1980 |
A facile tritium release assay for mammalian L-dihydroorotate dehydrogenase TW Kensler, DA Cooney, HN Jayaram, C Schaeffer, DD Choie Analytical biochemistry 117 (2), 315-319, 1981 | 8 | 1981 |
A genetic strategy to identify, validate and use gene signatures of xenobiotic-responsive transcription factors in prediction of pathway activation in the mouse liver K Oshida, N Vasani, M Rosen, B Abbott, C Lau, B Chorley, S Hester, ... DRUG METABOLISM REVIEWS 43, 183-184, 2011 | | 2011 |
A Highlights from MBoC Selection: Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence D Volonte, Z Liu, PM Musille, E Stoppani, N Wakabayashi, YP Di, ... Molecular Biology of the Cell 24 (12), 1852, 2013 | | 2013 |
A non-calcemic sulfone version of the vitamin D3 analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin GH Posner, KR Crawford, S Peleg, JE Welsh, S Romu, DA Gewirtz, ... Bioorganic & medicinal chemistry 9 (9), 2365-2371, 2001 | 34 | 2001 |
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin K Liby, MM Yore, BD Roebuck, KJ Baumgartner, T Honda, ... Cancer research 68 (16), 6727-6733, 2008 | 59 | 2008 |
A novel synthetic tricyclic compound with an acetylene group at C-8a and cyano enones in rings A and C is a potent multifunctional agent in vitro and suppresses the formation … K Liby, T Honda, M Yore, C Sundararajan, H Yoshizawa, R Risingsong, ... Molecular Cancer Therapeutics 6 (11_Supplement), B66-B66, 2007 | | 2007 |
A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells L Baird, K Taguchi, A Zhang, Y Takahashi, T Suzuki, TW Kensler, ... Redox Biology 66, 102845, 2023 | 7 | 2023 |
A point mutation at C151 of Keap1 of mice abrogates NRF2 signaling, cytoprotection in vitro, and hepatoprotection in vivo by bardoxolone methyl (CDDO-Me) T Gatbonton-Schwager, Y Yagishita, T Joshi, N Wakabayashi, ... Molecular pharmacology 104 (2), 51-61, 2023 | 5 | 2023 |
A ROLE FOR FREE-RADICALS IN THE PROCESS OF TUMOR PROMOTION BG TAFFE, TW KENSLER JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY 65 (4), 494-494, 1988 | | 1988 |