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Nan Zhang
Nan Zhang
Synerk Biotech; Houston Methodist Research Institute; Weill Cornell Medicine; Imperial College
在 synerk.com 的电子邮件经过验证
标题
引用次数
年份
A common feature from different subunits of a homomeric AAA+ protein contacts three spatially distinct transcription elements
N Zhang, N Joly, M Buck
Nucleic acids research 40 (18), 9139-9152, 2012
172012
A CRISPR-associated Rossmann fold (CARF) domain regulates transcription of an RNA repair system in Escherichia coli
I Kotta-Loizou, M Jovanovic, J Schaefer, C Engl, N Zhang, M Buck
Access Microbiology 1 (1A), 792, 2019
2019
A CRISPR-Cas13a based strategy that tracks and degrades toxic RNA in myotonic dystrophy type 1
N Zhang, B Bewick, G Xia, D Furling, T Ashizawa
Frontiers in Genetics 11, 594576, 2020
172020
A DNAZYME FOR CLEAVING CAG REPEAT RNA IN POLYGLUTAMINE DISEASES AND ELIMINATING VIRAL RNA IN CORONAVIRIDAE
N Zhang, T Ashizawa
US Patent App. 62/990,561, 2020
2020
A Key Hydrophobic Patch Identified in an AAA+ Protein Essential for Its In Trans Inhibitory Regulation
N Zhang, T Simpson, E Lawton, P Uzdavinys, N Joly, P Burrows, M Buck
Journal of molecular biology 425 (15), 2656-2669, 2013
112013
A perspective on the enhancer dependent bacterial RNA polymerase
N Zhang, M Buck
Biomolecules 5 (2), 1012-1019, 2015
402015
ATPase site architecture is required for self-assembly and remodeling activity of a hexameric AAA+ transcriptional activator
N Joly, N Zhang, M Buck
Molecular cell 47 (3), 484-490, 2012
312012
Coupling AAA protein function to regulated gene expression
N Joly, N Zhang, M Buck, X Zhang
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 108-116, 2012
492012
Determination of the self-association residues within a homomeric and a heteromeric AAA+ enhancer binding protein
E Lawton, M Jovanovic, N Joly, C Waite, N Zhang, B Wang, P Burrows, ...
Journal of Molecular Biology 426 (8), 1692-1710, 2014
82014
DNAzyme as a rising gene-silencing agent in theranostic settings
N Zhang
Neural Regen Res 17 (9), 1989-1990, 2022
62022
DNAzyme cleavage of CAG repeat RNA in polyglutamine diseases
N Zhang, B Bewick, J Schultz, A Tiwari, R Krencik, A Zhang, K Adachi, ...
Neurotherapeutics 18 (3), 1710-1728, 2021
122021
DNAZYME THAT TARGETS THE CAG REPEAT RNA IN POLYGLUTAMINE DISEASES
N Zhang, T Ashizawa
US Patent App. 62/987,072, 2020
2020
Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies
A Sharma, RN Leach, C Gell, N Zhang, PC Burrows, DA Shepherd, ...
Nucleic Acids Research 42 (8), 5177-5190, 2014
232014
Editorial: Neurodegeneration: From Disease Mechanism to Therapeutic Advancement
P Sarkar, G Meola, N Zhang
frontiers in genetics, 2022
2022
Engineered nucleic acids and uses thereof
N Zhang, T Ashizawa
US Patent App. 17/910,622, 2023
2023
ENGINEERED NUCLEIC ACIDS AND USES THEREOF
N Zhang, T Ashizawa
WO Patent WO2021183502A1, 2021
2021
Formation of MgF3−-dependent complexes between an AAA+ ATPase and σ54
N Zhang, M Buck
FEBS Open Bio 2, 89-92, 2012
72012
Functional studies of the'GAFTGA'motif of Escherichia coli Phage Shock Protein F
N Zhang
Imperial College London, 2011
12011
Genome wide interactions of wild-type and activator bypass forms of σ54
J Schaefer, C Engl, N Zhang, E Lawton, M Buck
Nucleic acids research 43 (15), 7280-7291, 2015
252015
Huntingtin Maintains Mitochondrial Genome Integrity and Function
S Pradhan, R Gao, K Bush, N Zhang, C Smith-Geater, A Chakraborty, ...
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