A common feature from different subunits of a homomeric AAA+ protein contacts three spatially distinct transcription elements N Zhang, N Joly, M Buck Nucleic acids research 40 (18), 9139-9152, 2012 | 17 | 2012 |
A CRISPR-associated Rossmann fold (CARF) domain regulates transcription of an RNA repair system in Escherichia coli I Kotta-Loizou, M Jovanovic, J Schaefer, C Engl, N Zhang, M Buck Access Microbiology 1 (1A), 792, 2019 | | 2019 |
A CRISPR-Cas13a based strategy that tracks and degrades toxic RNA in myotonic dystrophy type 1 N Zhang, B Bewick, G Xia, D Furling, T Ashizawa Frontiers in Genetics 11, 594576, 2020 | 17 | 2020 |
A DNAZYME FOR CLEAVING CAG REPEAT RNA IN POLYGLUTAMINE DISEASES AND ELIMINATING VIRAL RNA IN CORONAVIRIDAE N Zhang, T Ashizawa US Patent App. 62/990,561, 2020 | | 2020 |
A Key Hydrophobic Patch Identified in an AAA+ Protein Essential for Its In Trans Inhibitory Regulation N Zhang, T Simpson, E Lawton, P Uzdavinys, N Joly, P Burrows, M Buck Journal of molecular biology 425 (15), 2656-2669, 2013 | 11 | 2013 |
A perspective on the enhancer dependent bacterial RNA polymerase N Zhang, M Buck Biomolecules 5 (2), 1012-1019, 2015 | 40 | 2015 |
ATPase site architecture is required for self-assembly and remodeling activity of a hexameric AAA+ transcriptional activator N Joly, N Zhang, M Buck Molecular cell 47 (3), 484-490, 2012 | 31 | 2012 |
Coupling AAA protein function to regulated gene expression N Joly, N Zhang, M Buck, X Zhang Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (1), 108-116, 2012 | 49 | 2012 |
Determination of the self-association residues within a homomeric and a heteromeric AAA+ enhancer binding protein E Lawton, M Jovanovic, N Joly, C Waite, N Zhang, B Wang, P Burrows, ... Journal of Molecular Biology 426 (8), 1692-1710, 2014 | 8 | 2014 |
DNAzyme as a rising gene-silencing agent in theranostic settings N Zhang Neural Regen Res 17 (9), 1989-1990, 2022 | 6 | 2022 |
DNAzyme cleavage of CAG repeat RNA in polyglutamine diseases N Zhang, B Bewick, J Schultz, A Tiwari, R Krencik, A Zhang, K Adachi, ... Neurotherapeutics 18 (3), 1710-1728, 2021 | 12 | 2021 |
DNAZYME THAT TARGETS THE CAG REPEAT RNA IN POLYGLUTAMINE DISEASES N Zhang, T Ashizawa US Patent App. 62/987,072, 2020 | | 2020 |
Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies A Sharma, RN Leach, C Gell, N Zhang, PC Burrows, DA Shepherd, ... Nucleic Acids Research 42 (8), 5177-5190, 2014 | 23 | 2014 |
Editorial: Neurodegeneration: From Disease Mechanism to Therapeutic Advancement P Sarkar, G Meola, N Zhang frontiers in genetics, 2022 | | 2022 |
Engineered nucleic acids and uses thereof N Zhang, T Ashizawa US Patent App. 17/910,622, 2023 | | 2023 |
ENGINEERED NUCLEIC ACIDS AND USES THEREOF N Zhang, T Ashizawa WO Patent WO2021183502A1, 2021 | | 2021 |
Formation of MgF3−-dependent complexes between an AAA+ ATPase and σ54 N Zhang, M Buck FEBS Open Bio 2, 89-92, 2012 | 7 | 2012 |
Functional studies of the'GAFTGA'motif of Escherichia coli Phage Shock Protein F N Zhang Imperial College London, 2011 | 1 | 2011 |
Genome wide interactions of wild-type and activator bypass forms of σ54 J Schaefer, C Engl, N Zhang, E Lawton, M Buck Nucleic acids research 43 (15), 7280-7291, 2015 | 25 | 2015 |
Huntingtin Maintains Mitochondrial Genome Integrity and Function S Pradhan, R Gao, K Bush, N Zhang, C Smith-Geater, A Chakraborty, ... | | |