(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity WJ Valentine, GN Kiss, J Liu, E Shuyu, M Gotoh, K Murakami-Murofushi, ... Cellular signalling 22 (10), 1543-1553, 2010 | 64 | 2010 |
2D binary QSAR modeling of LPA3 receptor antagonism JI Fells, R Tsukahara, J Liu, G Tigyi, AL Parrill Journal of Molecular Graphics and Modelling 28 (8), 828-833, 2010 | 10 | 2010 |
314 DIFFERENTIAL ACTIVATION OF INTRACELLULAR SIGNALING BY HIGH GLUCOSE, METFORMIN, AND AICAR IN HUMAN MESANGIAL CELLS. E Gosmanova, G Tigyi, BM Wall Journal of Investigative Medicine 54 (1), S312, 2006 | | 2006 |
A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy B Hutka, A Várallyay, SB László, AS Tóth, B Scheich, S Paku, I Vörös, ... Acta Pharmacologica Sinica 45 (2), 339-353, 2024 | | 2024 |
A factor that activates oscillatory chloride currents in Xenopus oocytes copurifies with a subfraction of serum albumin. G Tigyi, A Henschen, R Miledi Journal of Biological Chemistry 266 (31), 20602-20609, 1991 | 78 | 1991 |
A glance at the structural and functional diversity of membrane lipids AM Dopico, GJ Tigyi Methods in membrane lipids, 1-13, 2007 | 40 | 2007 |
A luminacin D Analog HL142 inhibits ovarian Tumor Growth and Metastasis by reversing EMT and attenuating the TGFβ and FAK pathways B Wang, H Li, X Zhao, W Zhang, G Zhao, Z Wu, R Zhang, P Dong, ... Journal of Cancer 12 (18), 5654, 2021 | 3 | 2021 |
A new potential target for enhancing the anti-tumor T cell response: Lysophosphatidic acid signaling inhibits CD8+ T cell activation (127.29) S Oda, Y Fujiwara, T Oravecz, G Tigyi, R Pelanda, R Torres The Journal of Immunology 188 (1_Supplement), 127.29-127.29, 2012 | | 2012 |
A novel lipid mediator, cyclic phosphatidic acid (cPA), and its biological functions K MURAKAMI‐MUROFUSHI, M Mukai, S Kobayashi, T Kobayashi, G Tigyi, ... Annals of the New York Academy of Sciences 905 (1), 319-321, 2000 | 15 | 2000 |
A novel membrane receptor with high affinity for lysosphingomyelin and sphingosine 1‐phosphate in atrial myocytes. M Bünemann, K Liliom, BK Brandts, L Pott, JL Tseng, DM Desiderio, ... The EMBO Journal 15 (20), 5527-5534, 1996 | 137 | 1996 |
A protein complex of Phe508del-CFTR, NHERF2, and LPA2 regulates IL-8 secretion from airway epithelial cells Z Zhang, S Kong, GJ Tigyi, W Zhang A31. MECHANISMS IN CYSTIC FIBROSIS AND OTHER BRONCHIECTATIC DISEASES, A1283 …, 2017 | 1 | 2017 |
A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research NJ Pyne, GJ Tigyi Progress in Lipid Research 61, 19-29, 2016 | | 2016 |
A serum factor that activates the phosphatidylinositol phosphate signaling system in Xenopus oocytes. G Tigyi, D Dyer, C Matute, R Miledi Proceedings of the National Academy of Sciences 87 (4), 1521-1525, 1990 | 109 | 1990 |
A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors D Wang, Z Lorincz, DL Bautista, K Liliom, G Tigyi, AL Parrill Journal of Biological Chemistry 276 (52), 49213-49220, 2001 | 151 | 2001 |
A two-step approach to qPCR experimental design and software for data analysis H Guo, L Tague, R Ray, G Tigyi BMC Bioinformatics 11, 1-1, 2010 | 2 | 2010 |
A31 MECHANISMS IN CYSTIC FIBROSIS AND OTHER BRONCHIECTATIC DISEASES: A Protein Complex Of Phe508del-Cftr, Nherf2, And Lpa2 Regulates Il-8 Secretion From Airway Epithelial Cells Z Zhang, S Kong, GJ Tigyi, W Zhang American Journal of Respiratory and Critical Care Medicine 195, 2017 | | 2017 |
Abstract B28: Autotaxin, LPA1 and LPA5 receptors in the tumor microenvironment determine melanoma invasion and metastasis SC Lee, Y Fujiwara, J Liu, J Yue, R Tsukahara, E Szabo, R Patil, ... Cancer Research 75 (1_Supplement), B28-B28, 2015 | | 2015 |
Abstract LB054: Prometastatic effect of ATX derived from alveolar type II pneumocytes and B16F10 melanoma cells MA Dacheux, SC Lee, Y Shin, DD Norman, KH Lin, GJ Tigyi Cancer Research 82 (12_Supplement), LB054-LB054, 2022 | | 2022 |
Acetal phosphate-derived LPA mimics, PPARgamma activators, and autotaxin inhibitors D Miller, G Tigyi, V Gududuru, Y Fujiwara, D Baker, M Walker, G Durgam US Patent App. 11/418,561, 2006 | 19 | 2006 |
Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate M Fueller, DA Wang, G Tigyi, W Siess Cellular signalling 15 (4), 367-375, 2003 | 112 | 2003 |