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So Young Kim
So Young Kim
Assistant Research Professor, Duke University
在 duke.edu 的电子邮件经过验证
标题
引用次数
年份
A comparative oncology drug discovery pipeline to identify and validate new treatments for osteosarcoma
JA Somarelli, G Rupprecht, E Altunel, EM Flamant, S Rao, D Sivaraj, ...
Cancers 12 (11), 3335, 2020
142020
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
J Moffat, DA Grueneberg, X Yang, SY Kim, AM Kloepfer, G Hinkle, ...
Cell 124 (6), 1283-1298, 2006
20322006
A novel integrative genomic approach identifies CDK8 as a colon cancer oncogene
R Firestein, A Bass, SY Kim, I Dunn, S Silver, I Guney, E Freed, ...
Cancer Research 68 (9_Supplement), LB-282-LB-282, 2008
2008
A novel, high-throughput approach to discovering drug-resistance genes identifies CRAF, CrkL, and TPL2/COT as drivers of resistance to BRAFV600E inhibition
CM Johannessen, L Wardwell, SY Kim, J Boehm, S Thomas, LA Johnson, ...
Cancer Research 70 (8_Supplement), 5769-5769, 2010
2010
A precision medicine drug discovery pipeline to identify dual CDK2/9 inhibition as a novel treatment for colorectal cancer.
R Salman Roghani, A Sanjari moghaddam, G Rupprecht, E Altunel, ...
Journal of Clinical Oncology 38 (15_suppl), e16056-e16056, 2020
12020
A precision medicine strategy to identify the FGFR pathway as a novel target in colorectal cancer liver metastasis.
E Altunel, J Somarelli, SY Kim, W Glover, G Rupprecht, SD Hsu
Journal of Clinical Oncology 36 (4_suppl), 660-660, 2018
2018
A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer
KE Ware, BC Thomas, PD Olawuni, MU Sheth, N Hawkey, M Yeshwanth, ...
Frontiers in Molecular Biosciences 10, 1104505, 2023
42023
A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor
T Abaffy, JR Bain, MJ Muehlbauer, I Spasojevic, S Lodha, E Bruguera, ...
Frontiers in Oncology 8, 162, 2018
422018
Abstract P5-08-01: Systematic interrogation of resistance to HER2-directed therapy identifies a survival pathway activated by PRKACA and PIM1
SE Moody, AC Schinzel, S Singh, F Izzo, MR Strickland, LY Luo, ...
Cancer Research 73 (24_Supplement), P5-08-01-P5-08-01, 2013
2013
Abstract# 3822: PDK1-SGK3 signaling in the absence of AKT activation in PIK3CA-mutant cancers
K Vasudevan, D Barbie, M Davies, R Rabinovsky, B Hennessy, H Tseng, ...
Cancer Research 69 (9_Supplement), 3822-3822, 2009
22009
ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate
MM Keenan, B Liu, X Tang, J Wu, D Cyr, RD Stevens, O Ilkayeva, ...
PLoS genetics 11 (10), e1005599, 2015
402015
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer
KM Vasudevan, DA Barbie, MA Davies, R Rabinovsky, CJ McNear, ...
Cancer cell 16 (1), 21-32, 2009
6202009
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
T Nobukuni, M Joaquin, M Roccio, SG Dann, SY Kim, P Gulati, MP Byfield, ...
Proceedings of the National Academy of Sciences 102 (40), 14238-14243, 2005
9522005
Amplification and overexpresssion of IKBKE activates NF-kB pathway in breast cancers.
L Mulvey, J Boehm, I Dunn, SY Kim, J Yao, W Hahn, K Polyak
Cancer Research 67 (9_Supplement), 5261-5261, 2007
2007
An integrative systems biology and experimental approach identifies convergence of epithelial plasticity, metabolism, and autophagy to promote chemoresistance
S Xu, KE Ware, Y Ding, SY Kim, MU Sheth, S Rao, W Chan, AJ Armstrong, ...
Journal of Clinical Medicine 8 (2), 205, 2019
182019
bcSeq: an R package for fast sequence mapping in high-throughput shRNA and CRISPR screens
J Lin, J Gresham, T Wang, SY Kim, J Alvarez, JS Damrauer, S Floyd, ...
Bioinformatics 34 (20), 3581-3583, 2018
52018
Cancer genomics: integrating form and function
SY Kim, WC Hahn
Carcinogenesis 28 (7), 1387-1392, 2007
332007
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ...
Nature 455 (7212), 547-551, 2008
8042008
CK1ε is required for breast cancers dependent on β-catenin activity
SY Kim, IF Dunn, R Firestein, P Gupta, L Wardwell, K Repich, AC Schinzel, ...
PloS one 5 (2), e8979, 2010
1002010
Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and Pneumoviridae
DE Anderson, K Pfeffermann, SY Kim, B Sawatsky, J Pearson, M Kovtun, ...
MBio 10 (3), 10.1128/mbio. 00826-19, 2019
242019
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