关注
Nicolas Mercado
Nicolas Mercado
在 roche.com 的电子邮件经过验证
标题
引用次数
年份
168 CIRCULATING ENDOTHELIAL PROGENITOR CELLS IN SMOKERS ARE DYSFUNCTIONAL DUE TO INCREASED DNA DAMAGE AND SENESCENCE
KE Paschalaki, RD Starke, Y Hu, N Mercado, A Margariti, VG Gorgoulis, ...
Heart 99 (suppl 2), A97, 2013
2013
59 Endothelial colony forming cells (ECFC) are senescent and dysfunctional in COPD due to reduced sirtuin-1 levels
K Paschalaki, RD Starke, N Mercado, DO Haskard, PJ Barnes, AM Randi
Heart 97 (20), e7-e7, 2011
62011
A CARD10-dependent tonic signalosome activates MALT1 paracaspase and regulates IL-17/TNF-α-driven keratinocyte inflammation
L Israël, M Bardet, A Huppertz, N Mercado, S Ginster, A Unterreiner, ...
The Journal of investigative dermatology 138 (9), 2075-2079, 2018
222018
A novel target of formoterol, a dual-specificity phosphatase DUSP4 on regulation of corticosteroid budesonide sensitivity
Y Kobayashi, N Mercado, A Miller-Larsson, P Barnes, K Ito
European Respiratory Journal 38 (Suppl 55), 2011
2011
A role of mTOR in cigarette smoke-induced corticosteroid insensitivity
A Mitani, N Mercado, PJ Barnes, K Ito
European Respiratory Journal 40 (Suppl 56), 2012
12012
Accelerated ageing of the lung in COPD: new concepts
N Mercado, K Ito, PJ Barnes
Thorax 70 (5), 482-489, 2015
4222015
Activated protein phosphatase PP2A by formoterol enhances nuclear translocation of glucocorticoid receptor induced by budesonide
Y Kobayashi, N Mercado, A Miller-Larsson, P Barnes, K Ito
European Respiratory Journal 38 (Suppl 55), 2011
2011
Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers
N Mercado, Y Kizawa, K Ueda, Y Xiong, G Kimura, A Moses, JM Curtis, ...
PLoS One 9 (2), e88168, 2014
392014
AMPK signalling regulates Nrf2 localization and activity via sirtuins in a monocytic cell line
LN Naveira, N Mercado, K Ito
European Respiratory Journal 38 (Suppl 55), 2011
72011
An Activator Of AMP Activated Kinase (AMPK) Restores Nrf2 Protein Levels Decreased By Chronic Cigarette Smoke Exposure
N Mercado, A Turner, L Nunez Naveira, K Ito, PJ Barnes
A30. PULMONARY VICES: CIGARETTE SMOKE, ALCOHOL AND OXIDATIVE STRESS …, 2012
12012
Anti‐Ageing Strategy of the Lung for Chronic Inflammatory Respiratory Disease–Targeting Protein Deacetylases
K Ito, N Mercado
Molecular and Cellular Therapeutics, 125-139, 2012
2012
Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease
N Mercado, T Colley, JR Baker, C Vuppussetty, Y Kono, C Clarke, ...
FASEB bioAdvances 1 (11), 688, 2019
152019
Blood outgrowth endothelial cells are senescent and dysfunctional in COPD due to increased DNA damage; implications for endothelial dysfunction
K Paschalaki, R Starke, N Mercado, V Gorgoulis, AM Randi, PJ Barnes
European Respiratory Journal 40 (Suppl 56), 2012
2012
Bromodomain and extra-terminal (BET) proteins regulate antioxidant gene expression
C Michaeloudes, N Mercado, PJ Barnes, IM Adcock, KF Chung
European Respiratory Journal 42 (Suppl 57), 2013
2013
Bromodomain and extraterminal proteins suppress NF-E2–related factor 2–mediated antioxidant gene expression
C Michaeloudes, N Mercado, C Clarke, PK Bhavsar, IM Adcock, ...
The Journal of Immunology 192 (10), 4913-4920, 2014
722014
Cigarette smoke impairs autophagic flux in bronchial epithelial cells
N Mercado, T Colley, K Ito, P Barnes
European Respiratory Journal 42 (Suppl 57), 2013
32013
Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation
Y Kono, T Colley, M To, AI Papaioannou, N Mercado, JR Baker, Y To, ...
Scientific reports 11 (1), 335, 2021
282021
Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress
N Mercado, R Thimmulappa, CMR Thomas, PS Fenwick, KK Chana, ...
Biochemical and biophysical research communications 406 (2), 292-298, 2011
2362011
Defective sirtuin-1 increases IL-4 expression through acetylation of GATA-3 in patients with severe asthma
T Colley, N Mercado, Y Kunori, C Brightling, PK Bhavsar, PJ Barnes, K Ito
Journal of Allergy and Clinical Immunology 137 (5), 1595-1597. e7, 2016
422016
Defects of protein phosphatase 2A causes corticosteroid insensitivity in severe asthma
Y Kobayashi, N Mercado, PJ Barnes, K Ito
PloS one 6 (12), e27627, 2011
1142011
系统目前无法执行此操作,请稍后再试。
文章 1–20