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Simon Raffel
Simon Raffel
University Hospital Heidelberg
在 med.uni-heidelberg.de 的电子邮件经过验证
标题
引用次数
年份
3019–SINGLE-CELL PROTEO-GENOMIC REFERENCE MAPS OF THE HEMATOPOIETIC SYSTEM ENABLE THE PURIFICATION AND MASSIVE PROFILING OF PRECISELY DEFINED CELL STATES
D Vonficht, S Triana, L Jopp-Saile, S Raffel, R Lutz, D Leonce, M Antes, ...
Experimental Hematology 111, S54, 2022
2022
A CRISPR/Cas9 knockout screen identifies NAD plus kinase as a metabolic vulnerability in BCAT1 overexpressing AML cells
L Chung, M Antes, E Besiridou, M Monnig, A Demir, M Janssen, ...
ONCOLOGY RESEARCH AND TREATMENT 45 (SUPPL 2), 114-114, 2022
2022
A dynamic rRNA ribomethylome drives stemness in acute myeloid leukemia
F Zhou, N Aroua, Y Liu, C Rohde, J Cheng, AK Wirth, D Fijalkowska, ...
Cancer discovery 13 (2), 332-347, 2023
212023
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by …
C Stockklausner, S Raffel, J Klermund, OR Bandapalli, F Beier, ...
Aging (Albany NY) 7 (11), 911, 2015
172015
A specific ribomethylome pattern in lung cancer is associated with increased risk of metastasis
C Pauli, D Heid, C Rohde, N Krall, S Delaunay, M Kienhoefer, C Tischer, ...
Cancer Research 84 (6_Supplement), 2763-2763, 2024
2024
Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion
AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ...
Blood 132, 769, 2018
12018
Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ...
Nature 572 (7768), 254-259, 2019
3112019
ACUTE MYELOID LEUKEMIA EVOLUTION CAN BE RECONSTRUCTED BY ANALYSIS OF NON-LEUKEMIC CELLULAR SUBCOMPARTMENTS AND MULTI-LINEAGE ENGRAFTED MICE
BRM Saeed, L Manta, S Raffel, PT Pyl, W Wang, V Eckstein, A Trumpp, ...
HAEMATOLOGICA 102, 38-38, 2017
2017
Analysis of nonleukemic cellular subcompartments reconstructs clonal evolution of acute myeloid leukemia and identifies therapy‐resistant preleukemic clones
BR Saeed, L Manta, S Raffel, PT Pyl, EC Buss, W Wang, V Eckstein, ...
International journal of cancer 148 (11), 2825-2838, 2021
52021
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
P Hernández-Malmierca, D Vonficht, A Schnell, HJ Uckelmann, ...
Cell Stem Cell 29 (5), 760-775. e10, 2022
412022
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ...
Nature 560 (7718), E28-E28, 2018
32018
BCAT1 restricts alpha KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation (vol 551, pg 384, 2017)
S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ...
Nature 560 (7718), E28-E28, 2018
2018
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ...
Nature 551 (7680), 384-388, 2017
3292017
Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDHmut-Driven DNA Hypermethylation in AML Stem Cells
S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, G Poschet, ...
Blood 130, 472, 2017
2017
BRANCHED CHAIN AMINO ACID METABOLISM REGULATES ALPHA-KETOGLUTARATE HOMEOSTASIS RESEMBLING MUTANT-IDH DRIVEN DNA HYPERMETHYLATION IN AML
S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ...
HAEMATOLOGICA 102, 35-36, 2017
2017
CD127 is expressed by acute lymphoblastic leukemias and is efficiently targeted by Lusvertikimab (OSE-127) through IL-7Rα blockade and antibody dependent phagocytosis
I Baccelli, L Lenk, A Laqua, D Winterberg, A Dietterle, F Corallo, ...
CD127 is expressed by acute lymphoblastic leukemias and is efficiently targeted by the IL7R-antagonist OSE-127 through macrophage-mediated antibody dependent phagocytosis
I Baccelli, L Lenk, A Laqua, D Winterberg, A Dietterle, F Corallo, ...
Cancer Research 83 (7_Supplement), 2957-2957, 2023
12023
Cell Cycle and Differentiation Arrest in Senescent Population of Human Hematopoietic Stem and Progenitor Cell Compartment
L Poisa-Beiro, JJM Landry, S Raffel, V Eckstein, L Villacorta, AC Gavin, ...
Blood 140 (Supplement 1), 5751-5752, 2022
2022
Cells and Mediates Their Immune Evasion
AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ...
2019
Cellular hierarchies predict drug response in acute myeloid leukemia
S Raffel, L Velten, S Haas
Cancer Cell 40 (9), 917-919, 2022
2022
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