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A CRISPR/Cas9 knockout screen identifies NAD plus kinase as a metabolic vulnerability in BCAT1 overexpressing AML cells L Chung, M Antes, E Besiridou, M Monnig, A Demir, M Janssen, ... ONCOLOGY RESEARCH AND TREATMENT 45 (SUPPL 2), 114-114, 2022 | | 2022 |
A dynamic rRNA ribomethylome drives stemness in acute myeloid leukemia F Zhou, N Aroua, Y Liu, C Rohde, J Cheng, AK Wirth, D Fijalkowska, ... Cancer discovery 13 (2), 332-347, 2023 | 21 | 2023 |
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by … C Stockklausner, S Raffel, J Klermund, OR Bandapalli, F Beier, ... Aging (Albany NY) 7 (11), 911, 2015 | 17 | 2015 |
A specific ribomethylome pattern in lung cancer is associated with increased risk of metastasis C Pauli, D Heid, C Rohde, N Krall, S Delaunay, M Kienhoefer, C Tischer, ... Cancer Research 84 (6_Supplement), 2763-2763, 2024 | | 2024 |
Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ... Blood 132, 769, 2018 | 1 | 2018 |
Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ... Nature 572 (7768), 254-259, 2019 | 311 | 2019 |
ACUTE MYELOID LEUKEMIA EVOLUTION CAN BE RECONSTRUCTED BY ANALYSIS OF NON-LEUKEMIC CELLULAR SUBCOMPARTMENTS AND MULTI-LINEAGE ENGRAFTED MICE BRM Saeed, L Manta, S Raffel, PT Pyl, W Wang, V Eckstein, A Trumpp, ... HAEMATOLOGICA 102, 38-38, 2017 | | 2017 |
Analysis of nonleukemic cellular subcompartments reconstructs clonal evolution of acute myeloid leukemia and identifies therapy‐resistant preleukemic clones BR Saeed, L Manta, S Raffel, PT Pyl, EC Buss, W Wang, V Eckstein, ... International journal of cancer 148 (11), 2825-2838, 2021 | 5 | 2021 |
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool P Hernández-Malmierca, D Vonficht, A Schnell, HJ Uckelmann, ... Cell Stem Cell 29 (5), 760-775. e10, 2022 | 41 | 2022 |
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... Nature 560 (7718), E28-E28, 2018 | 3 | 2018 |
BCAT1 restricts alpha KG levels in AML stem cells leading to IDHmut-like DNA hypermethylation (vol 551, pg 384, 2017) S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... Nature 560 (7718), E28-E28, 2018 | | 2018 |
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... Nature 551 (7680), 384-388, 2017 | 329 | 2017 |
Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDHmut-Driven DNA Hypermethylation in AML Stem Cells S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, G Poschet, ... Blood 130, 472, 2017 | | 2017 |
BRANCHED CHAIN AMINO ACID METABOLISM REGULATES ALPHA-KETOGLUTARATE HOMEOSTASIS RESEMBLING MUTANT-IDH DRIVEN DNA HYPERMETHYLATION IN AML S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... HAEMATOLOGICA 102, 35-36, 2017 | | 2017 |
CD127 is expressed by acute lymphoblastic leukemias and is efficiently targeted by Lusvertikimab (OSE-127) through IL-7Rα blockade and antibody dependent phagocytosis I Baccelli, L Lenk, A Laqua, D Winterberg, A Dietterle, F Corallo, ... | | |
CD127 is expressed by acute lymphoblastic leukemias and is efficiently targeted by the IL7R-antagonist OSE-127 through macrophage-mediated antibody dependent phagocytosis I Baccelli, L Lenk, A Laqua, D Winterberg, A Dietterle, F Corallo, ... Cancer Research 83 (7_Supplement), 2957-2957, 2023 | 1 | 2023 |
Cell Cycle and Differentiation Arrest in Senescent Population of Human Hematopoietic Stem and Progenitor Cell Compartment L Poisa-Beiro, JJM Landry, S Raffel, V Eckstein, L Villacorta, AC Gavin, ... Blood 140 (Supplement 1), 5751-5752, 2022 | | 2022 |
Cells and Mediates Their Immune Evasion AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ... | | 2019 |
Cellular hierarchies predict drug response in acute myeloid leukemia S Raffel, L Velten, S Haas Cancer Cell 40 (9), 917-919, 2022 | | 2022 |